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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">porozendo</journal-id><journal-title-group><journal-title xml:lang="ru">Остеопороз и остеопатии</journal-title><trans-title-group xml:lang="en"><trans-title>Osteoporosis and Bone Diseases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-2680</issn><issn pub-type="epub">2311-0716</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/osteo12700</article-id><article-id custom-type="elpub" pub-id-type="custom">porozendo-12700</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Научный обзор</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Review</subject></subj-group></article-categories><title-group><article-title>Состояние проблемы остеопороза в странах Евразийского региона</article-title><trans-title-group xml:lang="en"><trans-title>Burden of Osteoporosis in the Countries of the Eurasian Region</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4839-4427</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Закроева</surname><given-names>Алла Геннадьевна</given-names></name><name name-style="western" xml:lang="en"><surname>Zakroyeva</surname><given-names>Alla G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., доцент</p></bio><bio xml:lang="en"><p>PhD</p></bio><email xlink:type="simple">zakroeva.alla@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9842-0246</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бабалян</surname><given-names>Варта Норайтовна</given-names></name><name name-style="western" xml:lang="en"><surname>Babalyan</surname><given-names>Varta</given-names></name></name-alternatives><email xlink:type="simple">vartababalyan@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5536-6227</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Габдулина</surname><given-names>Гульжан Хамзенична</given-names></name><name name-style="western" xml:lang="en"><surname>Gabdulina</surname><given-names>Guldjan</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., доцент</p></bio><bio xml:lang="en"><p>PhD, Assistant Professor</p></bio><email xlink:type="simple">gulzhan63@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8031-9083</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лобанченко</surname><given-names>Ольга Валерьевна</given-names></name><name name-style="western" xml:lang="en"><surname>Lobanchenko</surname><given-names>Оlga</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н.</p></bio><bio xml:lang="en"><p>PhD</p></bio><email xlink:type="simple">olga_lobanchenko@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7167-2187</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ершова</surname><given-names>Ольга Борисовна</given-names></name><name name-style="western" xml:lang="en"><surname>Ershova</surname><given-names>Оlga B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><bio xml:lang="en"><p>MD, PhD, Professor</p></bio><email xlink:type="simple">yarosteoporosis@list.ru</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0020-8464</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Исаева</surname><given-names>Cамал Мухаметкалиевна</given-names></name><name name-style="western" xml:lang="en"><surname>Issaeva</surname><given-names>Samal</given-names></name></name-alternatives><email xlink:type="simple">issayeva.s@kaznmu.kz</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4630-3985</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Исаева</surname><given-names>Бакытшолпан Габдулхакимовна</given-names></name><name name-style="western" xml:lang="en"><surname>Issaeva</surname><given-names>Bakytsholpan</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><bio xml:lang="en"><p>MD, PhD Professor</p></bio><email xlink:type="simple">issayeva.b@kaznmu.kz</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3744-4134</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Исмаилов</surname><given-names>Саид Ибрагимович</given-names></name><name name-style="western" xml:lang="en"><surname>Ismailov</surname><given-names>Said</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><bio xml:lang="en"><p>MD, PhD, Professor</p></bio><email xlink:type="simple">ismailov.said@list.ru</email><xref ref-type="aff" rid="aff-6"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1503-8880</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аббосхужаева</surname><given-names>Лола Сайдиганиходжаевна</given-names></name><name name-style="western" xml:lang="en"><surname>Abboshujaeva</surname><given-names>Lola</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н.</p></bio><bio xml:lang="en"><p>PhD</p></bio><email xlink:type="simple">abboskhujaeva82@mail.ru</email><xref ref-type="aff" rid="aff-7"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-5319-3828</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алиханова</surname><given-names>Нoдира Миршoвкатовна</given-names></name><name name-style="western" xml:lang="en"><surname>Alikhanova</surname><given-names>Nodira</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><bio xml:lang="en"><p>MD, PhD</p></bio><email xlink:type="simple">nodi200468@mail.ru</email><xref ref-type="aff" rid="aff-7"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9293-4481</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Казак</surname><given-names>Виктор Иванович</given-names></name><name name-style="western" xml:lang="en"><surname>Cazac</surname><given-names>Victor</given-names></name></name-alternatives><bio xml:lang="en"><p>MD</p></bio><email xlink:type="simple">cazacvictorion@gmail.com</email><xref ref-type="aff" rid="aff-8"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3822-3483</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Цагарели</surname><given-names>Марина Зурабовна</given-names></name><name name-style="western" xml:lang="en"><surname>Tsagareli</surname><given-names>Marina</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н.</p></bio><bio xml:lang="en"><p>MD, PhD</p></bio><email xlink:type="simple">tsagareli_marina@yahoo.com</email><xref ref-type="aff" rid="aff-9"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4881-4153</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Романов</surname><given-names>Георгий Никитич</given-names></name><name name-style="western" xml:lang="en"><surname>Ramanau</surname><given-names>Heorhi</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н., доцент</p></bio><bio xml:lang="en"><p>MD, PhD</p></bio><email xlink:type="simple">heorhi.ramanau@gmail.com</email><xref ref-type="aff" rid="aff-10"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4558-5930</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Руденко</surname><given-names>Эмма Владимировна</given-names></name><name name-style="western" xml:lang="en"><surname>Rudenkо</surname><given-names>Ema V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><bio xml:lang="en"><p>MD, PhD, Professor</p></bio><email xlink:type="simple">ema.rudenka@gmail.com</email><xref ref-type="aff" rid="aff-10"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4281-0880</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Руденко</surname><given-names>Елена Викторовна</given-names></name><name name-style="western" xml:lang="en"><surname>Rudenkо</surname><given-names>Alena V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>к.м.н.</p></bio><bio xml:lang="en"><p>MD, PhD, assistant professor</p></bio><email xlink:type="simple">alenka.v.ru@gmail.com</email><xref ref-type="aff" rid="aff-10"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-0143-0614</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лесняк</surname><given-names>Ольга Михайловна</given-names></name><name name-style="western" xml:lang="en"><surname>Lesnyak</surname><given-names>Olga M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>д.м.н., профессор</p></bio><bio xml:lang="en"><p>MD, PhD, professor</p></bio><email xlink:type="simple">olga.m.lesnyak@yandex.ru</email><xref ref-type="aff" rid="aff-11"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФГБОУ ВО «Уральский государственный медицинский университет»<country>Россия</country></aff><aff xml:lang="en">Ural State Medical University<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">Армянский центр остеопороза<country>Армения</country></aff><aff xml:lang="en">Armenian Osteoporosis Center<country>Armenia</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">Национальный медицинский университет им. Асфендиярова<country>Казахстан</country></aff><aff xml:lang="en">Asfendiyarov National Medical University<country>Kazakhstan</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru">Киргизская государственная медицинская академия им. И.К. Ахунбаева<country>Кыргызстан</country></aff><aff xml:lang="en">I.K. Akhunbaev Kyrgyz State Medical Academy<country>Kyrgyzstan</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru">ФГБОУ ВО «Ярославский государственный медицинский университет»<country>Россия</country></aff><aff xml:lang="en">Yaroslavl State Medical University<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru">Ташкентский педиатрический медицинский институт<country>Узбекистан</country></aff><aff xml:lang="en">Tashkent Pediatric Medical Institute<country>Uzbekistan</country></aff></aff-alternatives><aff-alternatives id="aff-7"><aff xml:lang="ru">Республиканский специализированный научно-практический медицинский центр эндокринологии им. акад. Я.Х. Туракулова<country>Узбекистан</country></aff><aff xml:lang="en">Republican Specialized Scientific and Practical Medical Endocrinology Center<country>Uzbekistan</country></aff></aff-alternatives><aff-alternatives id="aff-8"><aff xml:lang="ru">Государственный медицинский и фармацевтический университет имени Николаe Тестемицану<country>Молдова</country></aff><aff xml:lang="en">State University of Medicine and Pharmacy<country>Moldova, Republic of</country></aff></aff-alternatives><aff-alternatives id="aff-9"><aff xml:lang="ru">Национальный институт эндокринологии<country>Грузия</country></aff><aff xml:lang="en">National Institute of Endocrinology<country>Georgia</country></aff></aff-alternatives><aff-alternatives id="aff-10"><aff xml:lang="ru">Белорусский государственный медицинский университет<country>Беларусь</country></aff><aff xml:lang="en">Belarus State Medical University<country>Belarus</country></aff></aff-alternatives><aff-alternatives id="aff-11"><aff xml:lang="ru">ФГБОУ ВО «Северо-Западный государственный медицинский университет имени И.И. Мечникова» Минздрава России<country>Россия</country></aff><aff xml:lang="en">North West State Medical University named after I.I. Mechnikov<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>04</day><month>06</month><year>2021</year></pub-date><volume>23</volume><issue>4</issue><fpage>19</fpage><lpage>29</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Закроева А.Г., Бабалян В.Н., Габдулина Г.Х., Лобанченко О.В., Ершова О.Б., Исаева C.М., Исаева Б.Г., Исмаилов С.И., Аббосхужаева Л.С., Алиханова Н.М., Казак В.И., Цагарели М.З., Романов Г.Н., Руденко Э.В., Руденко Е.В., Лесняк О.М., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Закроева А.Г., Бабалян В.Н., Габдулина Г.Х., Лобанченко О.В., Ершова О.Б., Исаева C.М., Исаева Б.Г., Исмаилов С.И., Аббосхужаева Л.С., Алиханова Н.М., Казак В.И., Цагарели М.З., Романов Г.Н., Руденко Э.В., Руденко Е.В., Лесняк О.М.</copyright-holder><copyright-holder xml:lang="en">Zakroyeva A.G., Babalyan V., Gabdulina G., Lobanchenko О., Ershova О.B., Issaeva S., Issaeva B., Ismailov S., Abboshujaeva L., Alikhanova N., Cazac V., Tsagareli M., Ramanau H., Rudenkо E.V., Rudenkо A.V., Lesnyak O.M.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.osteo-endojournals.ru/jour/article/view/12700">https://www.osteo-endojournals.ru/jour/article/view/12700</self-uri><abstract><p>Оценка бремени остеопороза и остеопорозных переломов, основанная на результатах качественных научных проектов, на большей части территории бывшего СССР не проводилась.</p><sec><title>Цель</title><p>Цель. Анализ нализ эпидемиологических, медико-социальных и экономических аспектов проблемы остеопороза в восьми странах Евразийского региона, а также прогностические оценки ситуации на ближайшие годы.</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Был проведен поиск и критический анализ исследований, посвященных вопросам остеопороза, включая публикации местного или регионального значения на английском, русском или национальных языках, структурированный опрос представителей национальных обществ остеопороза Армении, Беларуси, Грузии, Казах- стана, Молдовы, Узбекистана, Кыргызской республики, Российской Федерации, изучение демографических тенденций в странах аудита.</p></sec><sec><title>Результаты</title><p>Результаты. Согласно эпидемиологическим данным, остеопороз является серьезной проблемой во всех странах. Ожидаемое количество больных остеопорозом варьирует от 240 тыс. в Армении до 16 млн в России. По данным многонационального проекта ЭВА, все страны аудита характеризует умеренный риск переломов проксимального отдела бедра для женщин (200–300 случаев на 100 000 в год). В Беларуси, Молдове, Армении, Грузии и Кыргызской республике риск умеренный как и для мужчин (100–150 на 100 000 в год). Россию, Узбекистан и Казахстан отличает высокий риск данного перелома у мужчин (выше 150 случаев на 100 000 в год). Сохраняющийся тренд на старение населения позволяет прогнозировать увеличение количества остеопорозных переломов во всем регионе. Вероятно, что к 2050 г. в наибольшей степени возрастет количество остеопорозных переломов в Узбекистане, Казахстане и Кыргызской республике — в 2,5–3,5 раза. Уровень госпитализации пациентов с переломом бедра в большинстве стран невысок (от 33% в Узбекистане до 80% в Кыргызской республике), обеспеченность диагностическим оборудованием недостаточна (0,2–1,3 на 1 млн), а исследования минеральной плотности кости (МПК) DXA дороги. И хотя большинство современных методов лечения остеопороза доступно, стоимость лечения остается высокой. Необходимы срочные действия на национальном уровне в каждой стране, включая признание остеопороза приоритетной проблемой здравоохранения.</p></sec><sec><title>Заключение</title><p>Заключение. Остеопороз — важная проблема здоровья в странах Евразийского региона, которая в будущем будет только усугубляться из-за ожидаемых демографических изменений.</p></sec></abstract><trans-abstract xml:lang="en"><p>The public health burden of osteoporosis estimated by the results of clinical and population-based researches in most of the former USSR is uncertain for today. The objective of this audit (Audit-2020) was the epidemiological, medico-social and economic analyse of current and future osteoporosis challenges for the future years for eight countries of the Eurasian region.</p><sec><title>Methods</title><p>Methods. We did a search and critical analysis of the publications, including of regional in English, Russian or national languages, did organize a structured survey among national osteoporosis societies members in Armenia, Belarus, Georgia, Kazakhstan, Moldova, Uzbekistan, Kyrgyz Republic, Russia, as well as explored the demographic trends in these countries.</p></sec><sec><title>Results</title><p>Results. Scientific researches including the wide population-based EVA project discovered that the expected number of patients with osteoporosis varies from 240,000 in Armenia to 16 million in Russia. All the countries should be categorized as a moderate risk of hip fractures for women (200–300 cases /100,000 per year). Belarus, Moldova, Armenia, Georgia and Kyrgyzstan have moderate risk for men (100–150/100,000), as well as Russia, Uzbekistan and Kazakhstan are distinguished by a high risk for men (over 150 cases/100,000). Population aging trends are predicting the future growth in the osteoporosis-associated health challenges throughout the region. It is likely the number of osteoporotic fractures to rise in Uzbekistan, Kazakhstan and Kyrgyzstan the most: 2.5–3.5 times by 2050. However current hospitalization rates for hip fracture persons are low in most countries (33–80%), the diagnostic equipment is insufficient (0.2–1.3 per million), DXA testing are expensive. Although modern treatments are available, the cure expenses remain high. Hereby, immediate action is required in each country of audit, including admit osteoporosis is a priority public health problem.</p></sec><sec><title>Conclusion</title><p>Conclusion. Osteoporosis is a challenge for the countries of the Eurasian region. Its burden is about to get worse due to the expected demographic changes.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>остеопороз</kwd><kwd>бремя</kwd><kwd>эпидемиология</kwd><kwd>переломы</kwd><kwd>Россия</kwd><kwd>Армения</kwd><kwd>Беларусь</kwd><kwd>Молдова</kwd><kwd>Казахстан</kwd><kwd>Узбекистан</kwd><kwd>Кыргызская республика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>osteoporosis</kwd><kwd>burden</kwd><kwd>epidemiology</kwd><kwd>fractures</kwd><kwd>Russia</kwd><kwd>Armenia</kwd><kwd>Belarus</kwd><kwd>Moldova</kwd><kwd>Kazakhstan</kwd><kwd>Uzbekistan</kwd><kwd>Kyrgyz Republic</kwd></kwd-group><funding-group xml:lang="ru"><funding-statement>Финансирование Аудита проводилось при финансовой поддержке Amgen, что включало оплату связи координатора с участниками рабочей группы, подготовку учебной документации и печать брошюры.</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Assessment of fracture risk and its application to screening for postmenopausal osteoporosis. 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