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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">porozendo</journal-id><journal-title-group><journal-title xml:lang="ru">Остеопороз и остеопатии</journal-title><trans-title-group xml:lang="en"><trans-title>Osteoporosis and Bone Diseases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-2680</issn><issn pub-type="epub">2311-0716</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/osteo12936</article-id><article-id custom-type="elpub" pub-id-type="custom">porozendo-12936</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Оригинальное исследование</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Original study</subject></subj-group></article-categories><title-group><article-title>Падения у пожилых пациентов: характеристика в зависимости от функционального статуса</article-title><trans-title-group xml:lang="en"><trans-title>Falls in older patients: characteristics depending on functional status</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3066-4866</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ховасова</surname><given-names>Н. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Khovasova</surname><given-names>N. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ховасова Наталья Олеговна, к.м.н., доцент </p><p>г. Москва, ул. 1-я Леонова, д. 16</p><p>SPIN: 7387-7710</p></bio><bio xml:lang="en"><p>Natalia O. Khovasova, PhD, associate Professor</p><p>Moscow, First Leonova str., 16</p><p>SPIN: 7387-7710</p></bio><email xlink:type="simple">natashahov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6253-621X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Наумов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Naumov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Наумов Антон Вячеславович, д.м.н., профессор </p><p>г. Москва</p><p>SPIN: 4763-9738</p></bio><bio xml:lang="en"><p>Anton V. Naumov, PhD</p><p>Moscow</p><p>SPIN: 4763-9738</p></bio><email xlink:type="simple">nanton78@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4193-688X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ткачева</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Tkacheva</surname><given-names>O. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ткачева Ольга Николаевна, д.м.н., профессор</p><p>г. Москва</p><p>SPIN: 6129-5809</p></bio><bio xml:lang="en"><p>Olga N. Tkacheva, PhD</p><p>Moscow</p><p>SPIN: 6129-5809</p></bio><email xlink:type="simple">ton@rgnkc.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-6040-1090</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мороз</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Moroz</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Мороз Виктория Иванова, ассистент</p><p>г. Москва</p><p>SPIN: 9739-6940</p></bio><bio xml:lang="en"><p>Victoriya I. Moroz, PhD</p><p>Moscow</p><p>SPIN: 9739-6940</p></bio><email xlink:type="simple">vikulya-moroz@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Кафедра болезней старения Российского национального исследовательского медицинского университета им. Н.И. Пирогова; Лаборатория заболеваний костно-мышечной системы, Российский геронтологический научно-клинический центр</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Department of diseases of aging of The Pirogov Russian National Research Medical University; Laboratory of the Musculoskeletal System Diseases, Russian Gerontology Clinical Research Center</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Кафедра болезней старения Российского национального исследовательского медицинского университета им. Н.И. Пирогова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Department of diseases of aging of The Pirogov Russian National Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>09</day><month>08</month><year>2022</year></pub-date><volume>25</volume><issue>1</issue><fpage>4</fpage><lpage>13</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ховасова Н.О., Наумов А.В., Ткачева О.Н., Мороз В.И., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Ховасова Н.О., Наумов А.В., Ткачева О.Н., Мороз В.И.</copyright-holder><copyright-holder xml:lang="en">Khovasova N.O., Naumov A.V., Tkacheva O.N., Moroz V.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.osteo-endojournals.ru/jour/article/view/12936">https://www.osteo-endojournals.ru/jour/article/view/12936</self-uri><abstract><sec><title>Обоснование</title><p>Обоснование. Падения и старческая астения (СА) — взаимосвязанные гериатрические синдромы. СА повышает риск падений, а падения — фактор прогрессирования СА. Выделение особенностей синдрома падений у пациентов с разным функциональным статусом позволит персонифицировать план профилактики падений и уменьшить прогрессирование СА.</p></sec><sec><title>Цель</title><p>Цель. Охарактеризовать падения у лиц пожилого возраста в зависимости от гериатрического статуса (без СА, с преастенией и с СА).</p></sec><sec><title>Материалы и методы</title><p>Материалы и методы. Включены 1002 пациента (77,5±8,2 года), госпитализированные в гериатрическое отделение. Проведен скрининг СА по шкале «Возраст не помеха». При сумме баллов 1–2 СА не диагностировалась. Таких пациентов было 321 (32%). При сумме баллов 3 и более проводилась комплексная гериатрическая оценка, после выделены еще 2 группы: с преастенией (n=199, 19,9%) и  СА (n=482, 48,1%). Выяснялся факт падений в течение года, при наличии — характеризовался синдром падений. Для анализа влияния падений на функциональный статус была проведена его оценка у пациентов с СА, перенесших падения и без таковых.</p></sec><sec><title>Результаты</title><p>Результаты. С нарастанием тяжести гериатрического статуса увеличивалась распространенность падений, достигая 57% у пациентов с СА. Пациенты с СА чаще падали дома. 300 (63,7%) человек ранее отмечали эпизоды падений, у 44,7% из них сформировался страх падений. Каждое 10-е падение завершилось серьезным последствием, что стало причиной госпитализации, но частота переломов и черепно-мозговых травм в группах не различалась. Риск падений увеличивался в зависимости от гериатрического дефицита: при СА пациентов с высоким риском было в 2 раза больше в сравнении с пациентами без СА.</p><p>У пациентов с СА и падениями по сравнению с пациентами без таковых, несмотря на более молодой возраст и меньшую коморбидность, функциональный статус был хуже. Они имели достоверно более низкий балл по краткой шкале оценки питания, более высокие баллы по шкале оценки здоровья и опроснику тревоги и дольше выполняли тест «5 подъемов со стула». Многофакторный анализ показал, что снижение суммы краткой батареи тестов физического функционирования на 0,35 и шкалы PHQ-9 на 0,77, повышение баллов по опроснику SARC-F на 0,68 и времени выполнения теста «5 подъемов со стула» на 3,39 с ассоциировано с падением у пожилых людей с СА с поправкой на возраст и коморбидность.</p></sec><sec><title>Заключение</title><p>Заключение. СА — условно обратимый синдром, а факт падений зачастую предотвратим. Учет выявленных особенностей синдрома падений у пациентов со сниженным функционированием позволит индивидуализировать план профилактики падений.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Background</title><p>Background: Falls and frailty are associated geriatric syndromes. Knowing the features of falls in patients with different functional status will make it possible to personalize the fall prevention and reduce the progression of frailty.</p></sec><sec><title>Aim</title><p>Aim: To characterise falls in older depending on geriatric status (robust, prefrailty and frailty).</p></sec><sec><title>Materials and methods</title><p>Materials and methods: Included 1002 patients (77,5±8,2) hospitalized in the geriatric department. The frailty was screened on the scale «Age Not Interference». With the score 1–2, frailty was not diagnosed. With the score 3 or more, comprehensive geriatric assessment was carried out and 2 more groups were allocated: with prefrailty (n=199, 19.9%) and with frailty (n=482,48.1%). All patients found out the fact of falls during the year, if there was, they were characterized by falls. To analyze the effect of falls on functional status, it was evaluated in patients with frailty and falls and frailty without falls.</p></sec><sec><title>Results</title><p>Results: With increasing severity of geriatric status, the prevalence of falls increased, reaching 57% in patients with frailty. 63.7% previously noted falls, 44.7% formed a fear of falls. One in 10 falls resulted in a serious consequence, which caused hospitalization. The risk of falls increased depending on geriatric deficiency: patients with frailty at high risk were 2 times greater compared to robust patients. The findings demonstrate that patients with frailty undergoing falls compared to patients without falls.</p><p>In patients with frailty and falls, compared to patients without falls, despite younger age and lower comorbidity, functional status was worse. They had a significantly lower score on the MNA, higher score on the PHQ-9 and anxiety score, and performed the chair stand longer. Multivariate analysis showed that a reduction in the sum of the SPPB by 0.35 and the PHQ-9 scale by 0.77, an increase in SARC-F by 0.68 and a time of performance of the chair stand by 3.39 seconds is associated with a fall in older people with frailty adjusted for age and comorbidity.</p></sec><sec><title>Conclusion</title><p>Conclusion: Frailty is a conditionally reversible syndrome, and falls is often prevented. Considering the identified features of falls in patients with reduced functioning will allow individualizing the fall prevention plan.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>падения</kwd><kwd>старческая астения</kwd><kwd>преастения</kwd><kwd>гериатрический синдром</kwd><kwd>функциональный статус</kwd></kwd-group><kwd-group xml:lang="en"><kwd>falls</kwd><kwd>frailty</kwd><kwd>prefrailty</kwd><kwd>geriatric syndrome</kwd><kwd>functional status</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Samper-Ternent R, Karmarkar A, Graham J, et al. Frailty as a predictor of falls in older Mexican Americans. J Aging Health. 2012;24(4):641-653. doi: https://doi.org/10.1177/0898264311428490</mixed-citation><mixed-citation xml:lang="en">Samper-Ternent R, Karmarkar A, Graham J, et al. Frailty as a predictor of falls in older Mexican Americans. J Aging Health. 2012;24(4):641-653. doi: https://doi.org/10.1177/0898264311428490</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Song X, Mitnitski A, Rockwood K. Prevalence and 10- year outcomes of frailty in older adults in relation to deficit accumulation. J Am Geriatr Soc. 2010;58(4):681-687. doi: https://doi.org/10.1111/j.1532-5415.2010.02764.x</mixed-citation><mixed-citation xml:lang="en">Song X, Mitnitski A, Rockwood K. Prevalence and 10- year outcomes of frailty in older adults in relation to deficit accumulation. J Am Geriatr Soc. 2010;58(4):681-687. doi: https://doi.org/10.1111/j.1532-5415.2010.02764.x</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Eeles EM, White SV, O’Mahony SM, et al. The impact of frailty and delirium on mortality in older inpatients. Age Ageing. 2012;41(3):412-416. doi: https://doi.org/10.1093/ageing/afs021.</mixed-citation><mixed-citation xml:lang="en">Eeles EM, White SV, O’Mahony SM, et al. The impact of frailty and delirium on mortality in older inpatients. Age Ageing. 2012;41(3):412-416. doi: https://doi.org/10.1093/ageing/afs021.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Cheng MH, Chang SF. Frailty as a Risk Factor for Falls Among Community Dwelling People: Evidence From a Meta-Analysis. J Nurs Scholarsh. 2017 Sep;49(5):529-536. doi: 10.1111/jnu.12322.</mixed-citation><mixed-citation xml:lang="en">Cheng MH, Chang SF. Frailty as a Risk Factor for Falls Among Community Dwelling People: Evidence From a Meta-Analysis. J Nurs Scholarsh. 2017 Sep;49(5):529-536. doi: 10.1111/jnu.12322.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Ткачева О.Н., Котовская Ю.В., Рунихина Н.К., и др. Клинические рекомендации «Старческая астения» // Российский журнал гериатрической медицины. — 2020. — №1. — С. 11-46. doi: https://doi.org/10.37586/2686-8636-1-2020-11-46</mixed-citation><mixed-citation xml:lang="en">Tkacheva ON, Kotovskaya YV, Runikhina NK, et al. Clinical guidelines on frailty. Russ J Geriatr Med. 2020;12(1):11-46. (In Russ.). doi: https://doi.org/10.37586/2686-8636-1-2020-11-46</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Ткачева О.Н., Котовская Ю.В., Рунихина Н.К., и др. Клинические рекомендации «Старческая астения». Часть 2 // Российский журнал гериатрической медицины. — 2020. — №2. — С. 115-130. doi: https://doi.org/10.37586/2686-8636-2-2020-115-130</mixed-citation><mixed-citation xml:lang="en">Tkacheva ON, Kotovskaya Y V., Runikhina NK, et al. Clinical guidelines frailty. Part 2. Russ J Geriatr Med. 2020;12(2):115-130. (In Russ.). doi: https://doi.org/10.37586/2686-8636-2-2020-115-130</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Вёрткин А.Л. Коморбидность: история, современное представление, профилактика и лечение // Кардиоваскулярная терапия и профилактика. — 2015. — Т. 14. — №2. — С. 74-79. doi: https://doi.org/10.15829/1728-8800-2015-2-74-79</mixed-citation><mixed-citation xml:lang="en">Vertkin AL. Comorbidity: history, recent views, prevention and treatment. Cardiovasc Ther Prev. 2015;14(2):74-79. (In Russ.). doi: https://doi.org/10.15829/1728-8800-2015-2-74-79</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Morley JE, Vellas B, van Kan GA, et al. Frailty consensus: a call to action. J Am Med Dir Assoc. 2013;14(6):392-397. doi: https://doi.org/10.1016/j.jamda.2013.03.022</mixed-citation><mixed-citation xml:lang="en">Morley JE, Vellas B, van Kan GA, et al. Frailty consensus: a call to action. J Am Med Dir Assoc. 2013;14(6):392-397. doi: https://doi.org/10.1016/j.jamda.2013.03.022</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Collard RM, Boter H, Schoevers RA, Oude Voshaar RC. Prevalence of frailty in community-dwelling older persons: a systematic review. J Am Geriatr Soc. 2012;60(8):1487-1492. doi: https://doi.org/10.1111/j.1532-5415.2012.04054.x</mixed-citation><mixed-citation xml:lang="en">Collard RM, Boter H, Schoevers RA, Oude Voshaar RC. Prevalence of frailty in community-dwelling older persons: a systematic review. J Am Geriatr Soc. 2012;60(8):1487-1492. doi: https://doi.org/10.1111/j.1532-5415.2012.04054.x</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Ma L, Chhetri JK, Chan P. Frailty in China: From Research to Practice. J Nutr Health Aging. 2021;25(4):479-483. doi: https://doi.org/10.1007/s12603-021-1593-7</mixed-citation><mixed-citation xml:lang="en">Ma L, Chhetri JK, Chan P. Frailty in China: From Research to Practice. J Nutr Health Aging. 2021;25(4):479-483. doi: https://doi.org/10.1007/s12603-021-1593-7</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Alves EVC, Flesch LD, Cachioni M, et al. The double vulnerability of elderly caregivers: multimorbidity and perceived burden and their associations with frailty. Rev Bras Geriatr Gerontol. 2018;21(3):301-11. doi: https://doi.org/10.1590/1981-22562018021.180050Alves</mixed-citation><mixed-citation xml:lang="en">Alves EVC, Flesch LD, Cachioni M, et al. The double vulnerability of elderly caregivers: multimorbidity and perceived burden and their associations with frailty. Rev Bras Geriatr Gerontol. 2018;21(3):301-11. doi: https://doi.org/10.1590/1981-22562018021.180050Alves</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Carneiro JA, Cardoso RR, Durães MS, et al. Frailty in the elderly: prevalence and associated factors. Rev Bras Enferm. 2017;70(4):747-752. doi: https://doi.org/10.1590/0034-7167-2016-0633</mixed-citation><mixed-citation xml:lang="en">Carneiro JA, Cardoso RR, Durães MS, et al. Frailty in the elderly: prevalence and associated factors. Rev Bras Enferm. 2017;70(4):747-752. doi: https://doi.org/10.1590/0034-7167-2016-0633</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Santos-Eggimann B, Cuénoud P, Spagnoli J, Junod J. Prevalence of frailty in middle-aged and older community-dwelling Europeans living in 10 countries. J Gerontol A Biol Sci Med Sci. 2009;64(6):675-681. doi: https://doi.org/10.1093/gerona/glp012</mixed-citation><mixed-citation xml:lang="en">Santos-Eggimann B, Cuénoud P, Spagnoli J, Junod J. Prevalence of frailty in middle-aged and older community-dwelling Europeans living in 10 countries. J Gerontol A Biol Sci Med Sci. 2009;64(6):675-681. doi: https://doi.org/10.1093/gerona/glp012</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Fried LP, Hadley EC, Walston JD, et al. From bedside to bench: research agenda for frailty. Sci Aging Knowledge Environ. 2005;2005(31):pe24. doi: https://doi.org/10.1126/sageke.2005.31.pe24</mixed-citation><mixed-citation xml:lang="en">Fried LP, Hadley EC, Walston JD, et al. From bedside to bench: research agenda for frailty. Sci Aging Knowledge Environ. 2005;2005(31):pe24. doi: https://doi.org/10.1126/sageke.2005.31.pe24</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Воробьева Н.М., Ховасова Н.О., Ткачева О.Н., и др. Падения и переломы у лиц старше 65 лет и их ассоциации с гериатрическими синдромами: данные российского эпидемиологического исследования ЭВКАЛИПТ // Российский журнал гериатрической медицины. — 2021. — Т. 14. — №2. — С. 219-229. doi: https://doi.org/10.37586/2686-8636-2-2021-209-219</mixed-citation><mixed-citation xml:lang="en">Vorobyeva NM, Khovasova NO, Tkacheva ON, et al. Falls and fractures in subjects over 65 years old and their associations with geriatric syndromes: Russian epidemiological study EVKALIPT. Russ J Geriatr Med. 2021;14(2):219-229. (In Russ.). doi: https://doi.org/10.37586/2686-8636-2-2021-209-219</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Gómez Jiménez E, Avendaño Céspedes A, Cortés Zamora EB, et al. Prevalencia de fragilidad en adultos mayores hospitalizados. Revisión sistemática [Frailty prevalence in hospitalized older adults. A systematic review.]. Rev Esp Salud Publica. 2021;95:e202110158.</mixed-citation><mixed-citation xml:lang="en">Gómez Jiménez E, Avendaño Céspedes A, Cortés Zamora EB, et al. Prevalencia de fragilidad en adultos mayores hospitalizados. Revisión sistemática [Frailty prevalence in hospitalized older adults. A systematic review.]. Rev Esp Salud Publica. 2021;95:e202110158.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Xue QL, Bandeen-Roche K, Tian J, et al. Progression of Physical Frailty and the Risk of All-Cause Mortality: Is There a Point of No Return? J Am Geriatr Soc. 2021;69(4):908-915. doi: https://doi.org/10.1111/jgs.16976</mixed-citation><mixed-citation xml:lang="en">Xue QL, Bandeen-Roche K, Tian J, et al. Progression of Physical Frailty and the Risk of All-Cause Mortality: Is There a Point of No Return? J Am Geriatr Soc. 2021;69(4):908-915. doi: https://doi.org/10.1111/jgs.16976</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">González-Vaca J, de la Rica-Escuín M, Silva-Iglesias M, et al. Frailty in INstitutionalized older adults from ALbacete. The FINAL Study: rationale, design, methodology, prevalence and attributes. Maturitas. 2014;77(1):78-84. doi: https://doi.org/10.1016/j.maturitas.2013.10.005</mixed-citation><mixed-citation xml:lang="en">González-Vaca J, de la Rica-Escuín M, Silva-Iglesias M, et al. Frailty in INstitutionalized older adults from ALbacete. The FINAL Study: rationale, design, methodology, prevalence and attributes. Maturitas. 2014;77(1):78-84. doi: https://doi.org/10.1016/j.maturitas.2013.10.005</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Mitchell R, Ting HP, Draper B, et al. Frailty and risk of rehospitalisation and mortality for aged care residents following a fall injury hospitalisation. Australas J Ageing. 2021;40(1):e44-e53. doi: https://doi.org/10.1111/ajag.12847</mixed-citation><mixed-citation xml:lang="en">Mitchell R, Ting HP, Draper B, et al. Frailty and risk of rehospitalisation and mortality for aged care residents following a fall injury hospitalisation. Australas J Ageing. 2021;40(1):e44-e53. doi: https://doi.org/10.1111/ajag.12847</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Bartosch PS, Kristensson J, McGuigan FE, Akesson KE. Frailty and prediction of recurrent falls over 10 years in a community cohort of 75-year-old women. Aging Clin Exp Res. 2020;32(11):2241-2250. doi: https://doi.org/10.1007/s40520-019-01467-1</mixed-citation><mixed-citation xml:lang="en">Bartosch PS, Kristensson J, McGuigan FE, Akesson KE. Frailty and prediction of recurrent falls over 10 years in a community cohort of 75-year-old women. Aging Clin Exp Res. 2020;32(11):2241-2250. doi: https://doi.org/10.1007/s40520-019-01467-1</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Gopinath B, McMahon CM, Burlutsky G, Mitchell P. Hearing and vision impairment and the 5-year incidence of falls in older adults. Age Ageing. 2016;45(3):409-414. doi: https://doi.org/10.1093/ageing/afw022</mixed-citation><mixed-citation xml:lang="en">Gopinath B, McMahon CM, Burlutsky G, Mitchell P. Hearing and vision impairment and the 5-year incidence of falls in older adults. Age Ageing. 2016;45(3):409-414. doi: https://doi.org/10.1093/ageing/afw022</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Almada M, Brochado P, Portela D, et al. Prevalence of Falls and Associated Factors among Community-Dwelling Older Adults: A Cross-Sectional Study. J Frailty Aging. 2021;10(1):10-16. doi: https://doi.org/10.14283/jfa.2020.44</mixed-citation><mixed-citation xml:lang="en">Almada M, Brochado P, Portela D, et al. Prevalence of Falls and Associated Factors among Community-Dwelling Older Adults: A Cross-Sectional Study. J Frailty Aging. 2021;10(1):10-16. doi: https://doi.org/10.14283/jfa.2020.44</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Jehu DA, Davis JC, Falck RS, et al. Risk factors for recurrent falls in older adults: A systematic review with meta-analysis. Maturitas. 2021;144:23-28. doi: https://doi.org/10.1016/j.maturitas.2020.10.021</mixed-citation><mixed-citation xml:lang="en">Jehu DA, Davis JC, Falck RS, et al. Risk factors for recurrent falls in older adults: A systematic review with meta-analysis. Maturitas. 2021;144:23-28. doi: https://doi.org/10.1016/j.maturitas.2020.10.021</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Stubbs B, Binnekade T, Eggermont L, et al. Pain and the risk for falls in community-dwelling older adults: systematic review and meta-analysis. Arch Phys Med Rehabil. 2014;95(1):175-187. doi: https://doi.org/10.1016/j.apmr.2013.08.241</mixed-citation><mixed-citation xml:lang="en">Stubbs B, Binnekade T, Eggermont L, et al. Pain and the risk for falls in community-dwelling older adults: systematic review and meta-analysis. Arch Phys Med Rehabil. 2014;95(1):175-187. doi: https://doi.org/10.1016/j.apmr.2013.08.241</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Alcolea-Ruiz N, Alcolea-Ruiz S, Esteban-Paredes F, et al. Prevalencia del miedo a caer y factores asociados en personas mayores que viven en la comunidad [Prevalence of fear of falling and related factors in communitydwelling older people]. Aten Primaria. 2021;53(2):101962. doi: https://doi.org/10.1016/j.aprim.2020.11.003</mixed-citation><mixed-citation xml:lang="en">Alcolea-Ruiz N, Alcolea-Ruiz S, Esteban-Paredes F, et al. Prevalencia del miedo a caer y factores asociados en personas mayores que viven en la comunidad [Prevalence of fear of falling and related factors in communitydwelling older people]. Aten Primaria. 2021;53(2):101962. doi: https://doi.org/10.1016/j.aprim.2020.11.003</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Fhon JRS, Rodriguez MMP, Morote GAG, et al. Risk of falls i the elderly to come to day two centers. Horiz Med. 2014;14(3):12-18.</mixed-citation><mixed-citation xml:lang="en">Fhon JRS, Rodriguez MMP, Morote GAG, et al. Risk of falls i the elderly to come to day two centers. Horiz Med. 2014;14(3):12-18.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Balzer K, Bremer M, Schramm S, et al. Falls prevention for the elderly. GMS Health Technol Assess. 2012;8:Doc01. doi: https://doi.org/10.3205/hta000099</mixed-citation><mixed-citation xml:lang="en">Balzer K, Bremer M, Schramm S, et al. Falls prevention for the elderly. GMS Health Technol Assess. 2012;8:Doc01. doi: https://doi.org/10.3205/hta000099</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Kojima G. Frailty significantly increases the risk of fractures among middle-aged and older people. Evid Based Nurs. 2017;20(4):119-120. doi: https://doi.org/10.1136/eb-2017-102769</mixed-citation><mixed-citation xml:lang="en">Kojima G. Frailty significantly increases the risk of fractures among middle-aged and older people. Evid Based Nurs. 2017;20(4):119-120. doi: https://doi.org/10.1136/eb-2017-102769</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Middleton R, Poveda JL, Orfila Pernas F, et al. Mortality, falls and fracture risk are positively associated with frailty: a SIDIAP cohort study of 890,000 patients. J Gerontol A Biol Sci Med Sci. 2021;77(1):148-154. doi: https://doi.org/10.1093/gerona/glab102</mixed-citation><mixed-citation xml:lang="en">Middleton R, Poveda JL, Orfila Pernas F, et al. Mortality, falls and fracture risk are positively associated with frailty: a SIDIAP cohort study of 890,000 patients. J Gerontol A Biol Sci Med Sci. 2021;77(1):148-154. doi: https://doi.org/10.1093/gerona/glab102</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Bartosch P, Malmgren L, Kristensson J, et al. In communitydwelling women frailty is associated with imminent risk of osteoporotic fractures. Osteoporos Int. 2021;32(9):1735-1744. doi: https://doi.org/10.1007/s00198-021-05886-7</mixed-citation><mixed-citation xml:lang="en">Bartosch P, Malmgren L, Kristensson J, et al. In communitydwelling women frailty is associated with imminent risk of osteoporotic fractures. Osteoporos Int. 2021;32(9):1735-1744. doi: https://doi.org/10.1007/s00198-021-05886-7</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Walston J, Hadley EC, Ferrucci L, et al. Research agenda for frailty in older adults: toward a better understanding of physiology and etiology: summary from the American Geriatrics Society/ National Institute on Aging Research Conference on Frailty in Older Adults. J Am Geriatr Soc. 2006;54(6):991-1001. doi: https://doi.org/10.1111/j.1532-5415.2006.00745.x</mixed-citation><mixed-citation xml:lang="en">Walston J, Hadley EC, Ferrucci L, et al. Research agenda for frailty in older adults: toward a better understanding of physiology and etiology: summary from the American Geriatrics Society/ National Institute on Aging Research Conference on Frailty in Older Adults. J Am Geriatr Soc. 2006;54(6):991-1001. doi: https://doi.org/10.1111/j.1532-5415.2006.00745.x</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Eeles EM, White SV, O’Mahony SM, et al. The impact of frailty and delirium on mortality in older inpatients. Age Ageing. 2012;41(3):412-416. doi: https://doi.org/10.1093/ageing/afs021</mixed-citation><mixed-citation xml:lang="en">Eeles EM, White SV, O’Mahony SM, et al. The impact of frailty and delirium on mortality in older inpatients. Age Ageing. 2012;41(3):412-416. doi: https://doi.org/10.1093/ageing/afs021</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Cameron ID, Gillespie LD, Robertson MC, et al. Interventions for preventing falls in older people in care facilities and hospitals. Cochrane Database Syst Rev. 2012;12:CD005465. doi: https://doi.org/10.1002/14651858.CD005465.pub3</mixed-citation><mixed-citation xml:lang="en">Cameron ID, Gillespie LD, Robertson MC, et al. Interventions for preventing falls in older people in care facilities and hospitals. Cochrane Database Syst Rev. 2012;12:CD005465. doi: https://doi.org/10.1002/14651858.CD005465.pub3</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
