porozendoОстеопороз и остеопатииOsteoporosis and Bone Diseases2072-26802311-0716Endocrinology Research Centre10.14341/osteo2011127-32porozendo-4130Research ArticleСтатьиArticlesМассивный остеолизис - синдром горхэма-стоутаMassive osteolysis - gorham-stout syndromeOttevaE. N.elvott@mail.ruKocherovaT. Yu.-ShepichevE. V.-OttevaE. N.-KocherovaT. Yu.-ShepichevE. V.-201115042011141№1 (2011)2732Copyright © Otteva E.N., Kocherova T.Y., Shepichev E.V., Otteva E.N., Kocherova T.Y., Shepichev E.V., 20112011Otteva E.N., Kocherova T.Y., Shepichev E.V., Otteva E.N., Kocherova T.Y., Shepichev E.V.Otteva E.N., Kocherova T.Y., Shepichev E.V., Otteva E.N., Kocherova T.Y., Shepichev E.V.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.osteo-endojournals.ru/jour/article/view/4130

В статье дано описание двух случаев одного из редких заболеваний - синдрома Gorham-Stout, который сопровождается массивным остеолизисом различных участков костной ткани. Приведен литературный обзор. Изолированный остеолизис отдельных участков кости протекает более доброкачественно без нарушения функции. Сочетание идиопатического остеолизиса с хилотораксом является неблагоприятным прогнозом. Лечение возможно кальцитонинами или бисфосфонатами.

The paper provides a detailed description of the two cases of one of the rarest diseases - Gorham-Stout syndrome. This syndrome is accompanied by the massive osteolysis of various sites of a bone tissue. The literary review is done. The isolated osteolysis of the separate bone parts is a non-malignant process, and it goes without abnormalities of its functions. The combination of osteolysis with chylothorax is an unfavorable process. The treatment of this disease is possible only by calcitonin or bisphosphonates.

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The authors declare that there are no conflicts of interest present.