porozendoОстеопороз и остеопатииOsteoporosis and Bone Diseases2072-26802311-0716Endocrinology Research Centre10.14341/osteo2012123-28porozendo-4208Research ArticleСтатьиArticlesНОВАЯ ПАРАДИГМА В ДИАГНОСТИКЕ И ЛЕЧЕНИИ ОСТЕОПОРОЗА: ПРОГНОЗИРОВАНИЕ 10-ЛЕТНЕГО АБСОЛЮТНОГО РИСКА ПЕРЕЛОМА (КАЛЬКУЛЯТОР FRAX™)THE NEW PARADIGM IN DIAGNOSIS AND TREATMENT OF OSTEOPOROSIS: PREDICTION OF A 10-YEAR ABSOLUTE RISK OF FRACTURE (CALCULATOR FRAX)LesnyakO. M.

kafedra semeynoy meditsiny FPK i PP

olga.m.lesnyak@yandex.ru201215042012151№1 (2012)2328Copyright © Lesnyak O.M., 20122012Lesnyak O.M.Lesnyak O.M.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.osteo-endojournals.ru/jour/article/view/4208

В обзоре обсуждается новый способ оценки вероятности перелома - 10-летний абсолютный риск перелома (калькулятор FRAX), выпущенный ВОЗ в 2008 г. Золотым стандартом диагностики остеопороза и прогнозирования риска перелома является двуэнергетическая рентгеновская абсорбциометрия (DXA). Цель разработки FRAX— улучшить прогностические возможности денситометрического исследования с помощью добавления к нему информации о наличии у пациента клинических факторов риска, независимых от минеральной плотности костной ткани. Приводится методология, использованная в выборе факторов риска для модели FRAX. Обсуждаются недостатки и ограничения FRAX, а также возможности его использования в клинической практике.

New tool to assess fracture probability — the 10-year absolute fracture risk (calculator FRAX), released by WHO in 2008 - is discussed in this review. Dual-energyX-rays absorptiometry (DXA) is considered as a gold standard of diagnosis of osteoporosis. The goal of FRAX was to improve the prognostic performance of densitometry in assessing fracture risk through adding the information on different clinical risk factors independent of bone mineral density. The methodology used in searching for the risk factors included in FRAX is reviewed. Disadvantages and limitations of FRAX as well as ways of it implementation in clinical practice are discussed.

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The authors declare that there are no conflicts of interest present.