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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">porozendo</journal-id><journal-title-group><journal-title xml:lang="ru">Остеопороз и остеопатии</journal-title><trans-title-group xml:lang="en"><trans-title>Osteoporosis and Bone Diseases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-2680</issn><issn pub-type="epub">2311-0716</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/osteo2008229-37</article-id><article-id custom-type="elpub" pub-id-type="custom">porozendo-4222</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>КАЛЬЦИМИМЕТИКИ - НОВЫЙ КЛАСС ПРЕПАРАТОВ ДЛЯ ЛЕЧЕНИЯ ГИПЕРПАРАТИРЕОЗА</article-title><trans-title-group xml:lang="en"><trans-title>KAL'TsIMIMETIKI - NOVYY KLASS PREPARATOV DLYa LEChENIYa GIPERPARATIREOZA</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="western" xml:lang="en"><surname>ROSTOMYaN</surname><given-names>L. G.</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="western" xml:lang="en"><surname>ROZhINSKAYa</surname><given-names>L. Ya.</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="western" xml:lang="en"><surname>EGShATYaN</surname><given-names>L. M.</given-names></name></name-alternatives><email xlink:type="simple">-</email></contrib></contrib-group><pub-date pub-type="collection"><year>2008</year></pub-date><pub-date pub-type="epub"><day>15</day><month>08</month><year>2008</year></pub-date><volume>11</volume><issue>2</issue><issue-title>№2 (2008)</issue-title><fpage>29</fpage><lpage>37</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; ROSTOMYaN L.G., ROZhINSKAYa L.Y., EGShATYaN L.M., 2008</copyright-statement><copyright-year>2008</copyright-year><copyright-holder xml:lang="ru">ROSTOMYaN L.G., ROZhINSKAYa L.Y., EGShATYaN L.M.</copyright-holder><copyright-holder xml:lang="en">ROSTOMYaN L.G., ROZhINSKAYa L.Y., EGShATYaN L.M.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.osteo-endojournals.ru/jour/article/view/4222">https://www.osteo-endojournals.ru/jour/article/view/4222</self-uri><abstract/><trans-abstract xml:lang="en"/></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Amann K., Tornig J., Kugel B., Gross M.L., Tyralla K., El-Shakmak A., Szabo A., Ritz E. Hyperphosphatemia aggravates cardiac fibrosis and microvascular disease in experimental uremia. Kidney Int 63: 1296-1301, 2003</mixed-citation><mixed-citation xml:lang="en">Amann K., Tornig J., Kugel B., Gross M.L., Tyralla K., El-Shakmak A., Szabo A., Ritz E. Hyperphosphatemia aggravates cardiac fibrosis and microvascular disease in experimental uremia. Kidney Int 63: 1296-1301, 2003</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Amann K., Ritz E., Wiest G., Klaus G., Mall G. A role of parathyroid hormone for the activation of cardiac fibroblasts in uremia. J Am Soc Nephrol 4: 1814-1819, 1994</mixed-citation><mixed-citation xml:lang="en">Amann K., Ritz E., Wiest G., Klaus G., Mall G. A role of parathyroid hormone for the activation of cardiac fibroblasts in uremia. J Am Soc Nephrol 4: 1814-1819, 1994</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Amann K., Tornig J., Flechtenmacher C., Nabokov A., Mall G., Ritz E. Blood-pressure-independent wall thickening of intramyocardial arterioles in experimental uraemia: Evidence for a permissive action of PTH. Nephrol Dial Transplant 10: 2043- 2048, 1995</mixed-citation><mixed-citation xml:lang="en">Amann K., Tornig J., Flechtenmacher C., Nabokov A., Mall G., Ritz E. Blood-pressure-independent wall thickening of intramyocardial arterioles in experimental uraemia: Evidence for a permissive action of PTH. Nephrol Dial Transplant 10: 2043- 2048, 1995</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Amgen Inc. Cinacalcet (Sensipar) US prescribing information [online]. Available from URL: &amp;lt;http://www.sensipar.com&amp;gt; [Accessed 2004 May 5]</mixed-citation><mixed-citation xml:lang="en">Amgen Inc. Cinacalcet (Sensipar) US prescribing information [online]. Available from URL: &amp;lt;http://www.sensipar.com&amp;gt; [Accessed 2004 May 5]</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Attie M.F., Gill J.R.Jr., Stock J.L., Spiegel A.M., Downs R.W.Jr., Levine M.A. et al. Urinary calcium excretion in familial hypocalciuric hypercalcemia. Persistence of relative hypocalciuria after induction of hypoparathyroidism. J Clin Invest 1983;72 (2):667-76.</mixed-citation><mixed-citation xml:lang="en">Attie M.F., Gill J.R.Jr., Stock J.L., Spiegel A.M., Downs R.W.Jr., Levine M.A. et al. Urinary calcium excretion in familial hypocalciuric hypercalcemia. Persistence of relative hypocalciuria after induction of hypoparathyroidism. J Clin Invest 1983;72 (2):667-76.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Barman Balfour J.A., Scott L.J. Cinacalcet Hydrochloride; Drugs 2005;65 (2); 271-281</mixed-citation><mixed-citation xml:lang="en">Barman Balfour J.A., Scott L.J. Cinacalcet Hydrochloride; Drugs 2005;65 (2); 271-281</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Baczynski R., Massry S.G., Kohan R., Magott M., Saglikes Y., Brautbar N. Effect of parathyroid hormone on myocardial energy metabolism in the rat. Kidney Int 27: 718-725, 1985</mixed-citation><mixed-citation xml:lang="en">Baczynski R., Massry S.G., Kohan R., Magott M., Saglikes Y., Brautbar N. Effect of parathyroid hormone on myocardial energy metabolism in the rat. Kidney Int 27: 718-725, 1985</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Block G.A., Hulbert-Shearon T.E., Levin N.W., Port F.K. Association of serum phosphorus and calcium x phosphate product with mortality risk in chronic hemodialysis patients: A national study. Am J Kidney Dis 31: 607-617, 1998</mixed-citation><mixed-citation xml:lang="en">Block G.A., Hulbert-Shearon T.E., Levin N.W., Port F.K. Association of serum phosphorus and calcium x phosphate product with mortality risk in chronic hemodialysis patients: A national study. Am J Kidney Dis 31: 607-617, 1998</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Block G.A., Martin K.J., de Francisco A.L., Turner S.A., Avram M.M., Suranyi M.G., Hercz G., Cunningham J., Abu-Alfa A.K., Messa P., Coyne D.W., Locatelli F., Cohen R.M., Evenepoel P., Moe S.M., Fournier A., Braun J., McCary L.C., Zani V.J., Olson K.A., Drueke T.B., Goodman W.G. Cinacalcet for secondary hyperparathyroidism in patients receiving hemodialysis. N Engl J Med 350: 1516-1525, 2004</mixed-citation><mixed-citation xml:lang="en">Block G.A., Martin K.J., de Francisco A.L., Turner S.A., Avram M.M., Suranyi M.G., Hercz G., Cunningham J., Abu-Alfa A.K., Messa P., Coyne D.W., Locatelli F., Cohen R.M., Evenepoel P., Moe S.M., Fournier A., Braun J., McCary L.C., Zani V.J., Olson K.A., Drueke T.B., Goodman W.G. Cinacalcet for secondary hyperparathyroidism in patients receiving hemodialysis. N Engl J Med 350: 1516-1525, 2004</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Bogin E., Massry S.G., Harary I. Effect of parathyroid hormone on rat heart cells. J Clin Invest 67: 1215-1227, 1981</mixed-citation><mixed-citation xml:lang="en">Bogin E., Massry S.G., Harary I. Effect of parathyroid hormone on rat heart cells. J Clin Invest 67: 1215-1227, 1981</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Brookman J., Farrow S., Nicholson L., O'Riordan J., and Hendy G. Regulation by calcium of parathyroid hormone mRNA in cultured parathyroid tissue. J Bone Miner Res 1: 529-537, 1986.</mixed-citation><mixed-citation xml:lang="en">Brookman J., Farrow S., Nicholson L., O'Riordan J., and Hendy G. Regulation by calcium of parathyroid hormone mRNA in cultured parathyroid tissue. J Bone Miner Res 1: 529-537, 1986.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Brown E.M. (1999). Physiology and pathophysiology of the extracellular calcium-sensing receptor. American Journal of Medicine,106: 238-253.</mixed-citation><mixed-citation xml:lang="en">Brown E.M. (1999). Physiology and pathophysiology of the extracellular calcium-sensing receptor. American Journal of Medicine,106: 238-253.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Brown E.M. Mechanisms underlying the regulation of parathyroid hormone secretion in vivo and in vitro. Curr Opin Nephrol Hypertens (1993) 2:541-551.</mixed-citation><mixed-citation xml:lang="en">Brown E.M. Mechanisms underlying the regulation of parathyroid hormone secretion in vivo and in vitro. Curr Opin Nephrol Hypertens (1993) 2:541-551.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Brown E.M., Hebert S.C. Calcium-receptor-regulated parathyroid and renal function. Bone 1997;20 (4):303-9.</mixed-citation><mixed-citation xml:lang="en">Brown E.M., Hebert S.C. Calcium-receptor-regulated parathyroid and renal function. Bone 1997;20 (4):303-9.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Brown E.M. Extracellular Ca2+ sensing, regulation of parathyroid cell function, and role of Ca2+ and other ions as extracellular (first) messengers. Physiol Rev 1991 ;71 (2):371-411.</mixed-citation><mixed-citation xml:lang="en">Brown E.M. Extracellular Ca2+ sensing, regulation of parathyroid cell function, and role of Ca2+ and other ions as extracellular (first) messengers. Physiol Rev 1991 ;71 (2):371-411.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Brown E.M., Gamba G., Riccardi D., Lombardi M., Butters R., Kifor O., Sun A., Hediger M.A., Lytton J., and Hebert S.C. Cloning and characterization of an extracellular Ca2+-sensing receptor from bovine parathyroid. Nature 366: 575-580, 1993.</mixed-citation><mixed-citation xml:lang="en">Brown E.M., Gamba G., Riccardi D., Lombardi M., Butters R., Kifor O., Sun A., Hediger M.A., Lytton J., and Hebert S.C. Cloning and characterization of an extracellular Ca2+-sensing receptor from bovine parathyroid. Nature 366: 575-580, 1993.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Chin J., Miller S.C., Wada M., Nagano N., Nemeth E.F. &amp;amp; Fox J. (2000). Activation of the calcium receptor by a calcimimetic compound halts the progression of secondary hyperparathyroidism in uremic rats. Journal of the American Society of Nephrology, 11: 903-911</mixed-citation><mixed-citation xml:lang="en">Chin J., Miller S.C., Wada M., Nagano N., Nemeth E.F. &amp;amp; Fox J. (2000). Activation of the calcium receptor by a calcimimetic compound halts the progression of secondary hyperparathyroidism in uremic rats. Journal of the American Society of Nephrology, 11: 903-911</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Chou Y.H., Pollak M.R., Brandi M.L., Toss G., Arnqvist H., Atkinson A.B., Papapoulos S.E., Marx S., Brown E.M., and Seidman J.G. Mutations in the human Ca2+-sensing-receptor gene that cause familial hypocalciuric hypercalcemia. Am J Hum Genet 56: 1075-1079, 1995.</mixed-citation><mixed-citation xml:lang="en">Chou Y.H., Pollak M.R., Brandi M.L., Toss G., Arnqvist H., Atkinson A.B., Papapoulos S.E., Marx S., Brown E.M., and Seidman J.G. Mutations in the human Ca2+-sensing-receptor gene that cause familial hypocalciuric hypercalcemia. Am J Hum Genet 56: 1075-1079, 1995.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Coburn J.W., Charytan C., Chonchol M., et al. Cinacalcet HCl is an effective treatment for secondary hyperparathyroidism (HPT) in patients with chronic kidney disease (CKD) not yet receiving dialysis [abstract # SA-P0740]. J Am Soc Nedrol 2003; 14 suppl.: 460A</mixed-citation><mixed-citation xml:lang="en">Coburn J.W., Charytan C., Chonchol M., et al. Cinacalcet HCl is an effective treatment for secondary hyperparathyroidism (HPT) in patients with chronic kidney disease (CKD) not yet receiving dialysis [abstract # SA-P0740]. J Am Soc Nedrol 2003; 14 suppl.: 460A</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Cole D.E.C., Peltekova V.D., Rubin L.A., Hawker G.A., Vieth R., Liew C.C. A 986S polymorphism of the calcium sensing receptor and circulating calcium concentration. Lancet 1999; 353:112-15;</mixed-citation><mixed-citation xml:lang="en">Cole D.E.C., Peltekova V.D., Rubin L.A., Hawker G.A., Vieth R., Liew C.C. A 986S polymorphism of the calcium sensing receptor and circulating calcium concentration. Lancet 1999; 353:112-15;</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Collins M.T., Skarulis M.C., Bilezikian J.P., Silverberg S.J., Spiegel A.M. &amp;amp; Marx S.J. (1998). Treatment of hypercalcemia secondary to parathyroid carcinoma with a novel calcimimetic agent. Journal of Clinical Endocrinology and Metabolism, 83: 1083-1088</mixed-citation><mixed-citation xml:lang="en">Collins M.T., Skarulis M.C., Bilezikian J.P., Silverberg S.J., Spiegel A.M. &amp;amp; Marx S.J. (1998). Treatment of hypercalcemia secondary to parathyroid carcinoma with a novel calcimimetic agent. Journal of Clinical Endocrinology and Metabolism, 83: 1083-1088</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Colloton M., Shatzen E., Miller G., et al. Cinacalcet HCl attenuates parathyroid hyperplasia in a rat model of secondary hyperparathyroidism. Kidney Int (2005) 67:467-476.</mixed-citation><mixed-citation xml:lang="en">Colloton M., Shatzen E., Miller G., et al. Cinacalcet HCl attenuates parathyroid hyperplasia in a rat model of secondary hyperparathyroidism. Kidney Int (2005) 67:467-476.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Conigrave A.D., Poronnik P., Delbridge L., Young J.A., and Cook D.I. An inwardly rectifying K+ channel in human adenomatous parathyroid cells. Cell Calcium 14: 517-523, 1993.</mixed-citation><mixed-citation xml:lang="en">Conigrave A.D., Poronnik P., Delbridge L., Young J.A., and Cook D.I. An inwardly rectifying K+ channel in human adenomatous parathyroid cells. Cell Calcium 14: 517-523, 1993.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Cunningham J., Urena P., Reichel H., et al. Long term efficacy of cinacalcet in secondary hyperparathyroidism (HPT) of end stage renal disease (ESRD): abstract SP210, ERA-EDTA 2005. Nephrol Dial Transplant (2005) 20(Suppl 5):V89.</mixed-citation><mixed-citation xml:lang="en">Cunningham J., Urena P., Reichel H., et al. Long term efficacy of cinacalcet in secondary hyperparathyroidism (HPT) of end stage renal disease (ESRD): abstract SP210, ERA-EDTA 2005. Nephrol Dial Transplant (2005) 20(Suppl 5):V89.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Delmez J.A., Kelber J., Noamgenood K.Y., Giles K.S., and Slatopolsky E. A controlled trial of the early treatment of secondary hyperparathyroidism with calcitriol in hemodialysis patients. Clin Nephrol 54: 301-308, 2000.</mixed-citation><mixed-citation xml:lang="en">Delmez J.A., Kelber J., Noamgenood K.Y., Giles K.S., and Slatopolsky E. A controlled trial of the early treatment of secondary hyperparathyroidism with calcitriol in hemodialysis patients. Clin Nephrol 54: 301-308, 2000.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Doroszewicz J., Waldegger P., Jeck N., Seyberth H., Waldegger S. pH dependence of extracellular calcium sensing receptor activity determined by a novel technique. Kidney Int 2005;67 (1):187-92</mixed-citation><mixed-citation xml:lang="en">Doroszewicz J., Waldegger P., Jeck N., Seyberth H., Waldegger S. pH dependence of extracellular calcium sensing receptor activity determined by a novel technique. Kidney Int 2005;67 (1):187-92</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Edward M. Brown and R. John MacLeod Extracellular Calcium Sensing and Extracellular Calcium Signaling Physiological Reviews, Vol. 81, No. 1, January 2001, pp. 239-297</mixed-citation><mixed-citation xml:lang="en">Edward M. Brown and R. John MacLeod Extracellular Calcium Sensing and Extracellular Calcium Signaling Physiological Reviews, Vol. 81, No. 1, January 2001, pp. 239-297</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Foley R.N., Murray A.M., Li S., Herzog C.A., McBean A.M., Eggers P.W., Collins A.J. Chronic kidney disease and the risk for cardiovascular disease, renal replacement, and death in the United States medicare population, 1998 to 1999. J Am Soc Nephrol 16: 489-495, 2005</mixed-citation><mixed-citation xml:lang="en">Foley R.N., Murray A.M., Li S., Herzog C.A., McBean A.M., Eggers P.W., Collins A.J. Chronic kidney disease and the risk for cardiovascular disease, renal replacement, and death in the United States medicare population, 1998 to 1999. J Am Soc Nephrol 16: 489-495, 2005</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Fox J., Lowe S.H., Conklin R.L., Nemeth E.F. The calcimimetic NPS R-568 decreases plasma PTH in rats with mild and severe renal or dietary secondary hyperparathyroidism. Endocrine (1999) 10:97-103.</mixed-citation><mixed-citation xml:lang="en">Fox J., Lowe S.H., Conklin R.L., Nemeth E.F. The calcimimetic NPS R-568 decreases plasma PTH in rats with mild and severe renal or dietary secondary hyperparathyroidism. Endocrine (1999) 10:97-103.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Fukuda N., Tanaka H., Tominaga Y., Fukagawa M., Kurokawa K., and Seino Y. Decreased 1,25-dihydroxyvitamin D3 receptor density is associated with a more severe form of parathyroid hyperplasia in chronic uremic patients. J Clin Invest 92: 1436-1443, 1993</mixed-citation><mixed-citation xml:lang="en">Fukuda N., Tanaka H., Tominaga Y., Fukagawa M., Kurokawa K., and Seino Y. Decreased 1,25-dihydroxyvitamin D3 receptor density is associated with a more severe form of parathyroid hyperplasia in chronic uremic patients. J Clin Invest 92: 1436-1443, 1993</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Ganesh S.K., Stack A.G., Levin N.W., Hulbert-Shearon T., Port F.K. Association of elevated serum PO(4), Ca x PO(4) product, and parathyroid hormone with cardiac mortality risk in chronic hemodialysis patients. J Am Soc Nephrol 12: 2131- 2138, 2001</mixed-citation><mixed-citation xml:lang="en">Ganesh S.K., Stack A.G., Levin N.W., Hulbert-Shearon T., Port F.K. Association of elevated serum PO(4), Ca x PO(4) product, and parathyroid hormone with cardiac mortality risk in chronic hemodialysis patients. J Am Soc Nephrol 12: 2131- 2138, 2001</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Garrett J.E., Capuano I.V., Hammerland L.G., Hung B.C., Brown E.M., Hebert S.C., et al. Molecular cloning and functional expression of human parathyroid calcium receptor cDNAs. J Biol Chem 1995;270 (21):12919-25.</mixed-citation><mixed-citation xml:lang="en">Garrett J.E., Capuano I.V., Hammerland L.G., Hung B.C., Brown E.M., Hebert S.C., et al. Molecular cloning and functional expression of human parathyroid calcium receptor cDNAs. J Biol Chem 1995;270 (21):12919-25.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Giachelli C.M., Jono S., Shioi A., Nishizawa Y., Mori K., Morii H. Vascular calcification and inorganic phosphate. Am J Kidney Dis 38: S34 -S37, 2001</mixed-citation><mixed-citation xml:lang="en">Giachelli C.M., Jono S., Shioi A., Nishizawa Y., Mori K., Morii H. Vascular calcification and inorganic phosphate. Am J Kidney Dis 38: S34 -S37, 2001</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Giachelli C.M. Vascular calcification: In vitro evidence for the role of inorganic phosphate. J Am Soc Nephrol 14[Suppl 4]: S300 -S304, 2003</mixed-citation><mixed-citation xml:lang="en">Giachelli C.M. Vascular calcification: In vitro evidence for the role of inorganic phosphate. J Am Soc Nephrol 14[Suppl 4]: S300 -S304, 2003</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Goodman W.G. Recent developments in the management of secondary hyperparathyroidism. Kidney Int 59: 1187-1201, 2001.</mixed-citation><mixed-citation xml:lang="en">Goodman W.G. Recent developments in the management of secondary hyperparathyroidism. Kidney Int 59: 1187-1201, 2001.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Goodman W.G. Calcimimetic agents and secondary hyperparathyroidism: rationale for use and results from clinical trials. Pediatr Nefrol 2003 dec; 18 (12):1206-10</mixed-citation><mixed-citation xml:lang="en">Goodman W.G. Calcimimetic agents and secondary hyperparathyroidism: rationale for use and results from clinical trials. Pediatr Nefrol 2003 dec; 18 (12):1206-10</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Goodman W.G., Goldin G., Kuizon B.D. et al. Coronaryartery calcification in young adults with end-stage renal disease who are undergoing dialysis. N Eng G Med 2000; 342: 1478-83</mixed-citation><mixed-citation xml:lang="en">Goodman W.G., Goldin G., Kuizon B.D. et al. Coronaryartery calcification in young adults with end-stage renal disease who are undergoing dialysis. N Eng G Med 2000; 342: 1478-83</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Goodman W.G., Frazao J.M., Goodkin D.A., Turner S.A., Liu W. &amp;amp; Coburn J.W. (2000). A calcimimetic agent lowers plasma parathyroid hormone levels in patients with secondary hyperparathyroidism. Kidney International, 58: 436-445</mixed-citation><mixed-citation xml:lang="en">Goodman W.G., Frazao J.M., Goodkin D.A., Turner S.A., Liu W. &amp;amp; Coburn J.W. (2000). A calcimimetic agent lowers plasma parathyroid hormone levels in patients with secondary hyperparathyroidism. Kidney International, 58: 436-445</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Goodman W.G., Hladik G.A., Turner S.A., Blaisdell P.W., Goodkin D.A., Liu W., Barri Y.M., Cohen R.M., and Coburn J.W. The calcimimetic agent AMG 073 lowers plasma parathyroid hormone levels in hemodialysis patients with secondary hyperparathyroidism. J Am Soc Nephrol 13: 1017-1024, 2002.</mixed-citation><mixed-citation xml:lang="en">Goodman W.G., Hladik G.A., Turner S.A., Blaisdell P.W., Goodkin D.A., Liu W., Barri Y.M., Cohen R.M., and Coburn J.W. The calcimimetic agent AMG 073 lowers plasma parathyroid hormone levels in hemodialysis patients with secondary hyperparathyroidism. J Am Soc Nephrol 13: 1017-1024, 2002.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Gowen M., Stroup G.B., Dodds R.A., James I.E., Votta B.J., Smith B.R., Bhatnagar P.K., Lago A.M., Callahan J.F., DelMar E.G., Miller M.A., Nemeth E.F. &amp;amp; Fox J. (2000). Antagonizing the parathyroid calcium receptor stimulates parathyroid hormone secretion and bone formation in osteopenic rats. Journal of Clinical Investigation, 105: 1595-1604</mixed-citation><mixed-citation xml:lang="en">Gowen M., Stroup G.B., Dodds R.A., James I.E., Votta B.J., Smith B.R., Bhatnagar P.K., Lago A.M., Callahan J.F., DelMar E.G., Miller M.A., Nemeth E.F. &amp;amp; Fox J. (2000). Antagonizing the parathyroid calcium receptor stimulates parathyroid hormone secretion and bone formation in osteopenic rats. Journal of Clinical Investigation, 105: 1595-1604</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Hammerland L.G., Garrett J.E., Hung B.C.P., Levinthal C., Nemeth E.F. Allosteric activation of the Ca2+ receptor expressed in Xenopus laevis oocytes by NPS 467 or NPS 568. Mol Pharmacol 1998;53 (6):1083-8.</mixed-citation><mixed-citation xml:lang="en">Hammerland L.G., Garrett J.E., Hung B.C.P., Levinthal C., Nemeth E.F. Allosteric activation of the Ca2+ receptor expressed in Xenopus laevis oocytes by NPS 467 or NPS 568. Mol Pharmacol 1998;53 (6):1083-8.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Hauache O.M., Hu J., Ray K., Xie R., Jacobson K.A. &amp;amp; Spiegel A.M. (2000). Effects of a calcimimetic compound and naturally activating mutations on the human Ca2+ receptor and on Ca2+ receptor/metabotropic glutamate chimeric receptors. Endocrinology, 141: 4156-4163</mixed-citation><mixed-citation xml:lang="en">Hauache O.M., Hu J., Ray K., Xie R., Jacobson K.A. &amp;amp; Spiegel A.M. (2000). Effects of a calcimimetic compound and naturally activating mutations on the human Ca2+ receptor and on Ca2+ receptor/metabotropic glutamate chimeric receptors. Endocrinology, 141: 4156-4163</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Hauache O.M. Extracellular calcium-sensing receptor: Structural and functional features and association with diseases. Braz J Med Biol Res 2001;34 (5):577-84.</mixed-citation><mixed-citation xml:lang="en">Hauache O.M. Extracellular calcium-sensing receptor: Structural and functional features and association with diseases. Braz J Med Biol Res 2001;34 (5):577-84.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Hebert S.C. Extracellular calcium-sensing receptor: Implications for calcium and magnesium handling in the kidney. Kidney Int 1996;50 (6):2129-39</mixed-citation><mixed-citation xml:lang="en">Hebert S.C. Extracellular calcium-sensing receptor: Implications for calcium and magnesium handling in the kidney. Kidney Int 1996;50 (6):2129-39</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">Hebert S.C., Brown E.M., Harris H.W. Role of the Ca(2+)-sensing receptor in divalent mineral ion homeostasis. J Exp Biol 1997;200(Pt 2):295-302</mixed-citation><mixed-citation xml:lang="en">Hebert S.C., Brown E.M., Harris H.W. Role of the Ca(2+)-sensing receptor in divalent mineral ion homeostasis. J Exp Biol 1997;200(Pt 2):295-302</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Hedback G., Oden A. Increased risk of death from primary hyperparathyroidism-An update. Eur J Clin Invest 28: 271-276, 1998</mixed-citation><mixed-citation xml:lang="en">Hedback G., Oden A. Increased risk of death from primary hyperparathyroidism-An update. Eur J Clin Invest 28: 271-276, 1998</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Hofer A.M., Brown E.M. Extracellular calcium sensing and signalling. Nat Rev Mol Cell Biol 4: 530-538, 2003</mixed-citation><mixed-citation xml:lang="en">Hofer A.M., Brown E.M. Extracellular calcium sensing and signalling. Nat Rev Mol Cell Biol 4: 530-538, 2003</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Jensen B., Farach-Carson M.C., Kenaley E., Akanbi K.A. High extracellular calcium attenuates adipogenesis in 3T3-L1 preadipocytes. Exp Cell Res 301: 280-292, 2004</mixed-citation><mixed-citation xml:lang="en">Jensen B., Farach-Carson M.C., Kenaley E., Akanbi K.A. High extracellular calcium attenuates adipogenesis in 3T3-L1 preadipocytes. Exp Cell Res 301: 280-292, 2004</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Kanazirska M.P., Vassilev P.M., Ye C.P., Francis J.E., and Brown E.M. Intracellular Ca2+-activated K+ channels modulated by variations in extracellular Ca2+ in dispersed bovine parathyroid cells. Endocrinology 136: 2238-2243, 1995</mixed-citation><mixed-citation xml:lang="en">Kanazirska M.P., Vassilev P.M., Ye C.P., Francis J.E., and Brown E.M. Intracellular Ca2+-activated K+ channels modulated by variations in extracellular Ca2+ in dispersed bovine parathyroid cells. Endocrinology 136: 2238-2243, 1995</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Kawata T., Imanishi Y., Kobayashi K., et al. Relationship between parathyroid calcium-sensing receptor expression and potency of the calcimimetic, cinacalcet, in suppressing parathyroid hormone secretion in an in vivo murine model of primary hyperparathyroidism. Eur J Endocrinol (2005) 153:587-594.</mixed-citation><mixed-citation xml:lang="en">Kawata T., Imanishi Y., Kobayashi K., et al. Relationship between parathyroid calcium-sensing receptor expression and potency of the calcimimetic, cinacalcet, in suppressing parathyroid hormone secretion in an in vivo murine model of primary hyperparathyroidism. Eur J Endocrinol (2005) 153:587-594.</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Kifor O., Moore F.D.J.R., Wang P., Goldstein M., Vassilev P., Kifor I., Hebert S.C., and Brown E.M. Reduced immunostaining for the extracellular Ca2+-sensing receptor in primary and uremic secondary hyperparathyroidism. J Clin Endocrinol Metab 81: 1598-1606, 1996.</mixed-citation><mixed-citation xml:lang="en">Kifor O., Moore F.D.J.R., Wang P., Goldstein M., Vassilev P., Kifor I., Hebert S.C., and Brown E.M. Reduced immunostaining for the extracellular Ca2+-sensing receptor in primary and uremic secondary hyperparathyroidism. J Clin Endocrinol Metab 81: 1598-1606, 1996.</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">Levi R., Ben-Dov I.Z., Lavi-Moshayoff V., et al. Increased parathyroid hormone gene expression in secondary hyperparathyroidism of experimental uremia is reversed by calcimimetics: correlation with post-translational modification of the trans acting factor AUF1. J Am Soc Nephrol (2006) 17:107-112.</mixed-citation><mixed-citation xml:lang="en">Levi R., Ben-Dov I.Z., Lavi-Moshayoff V., et al. Increased parathyroid hormone gene expression in secondary hyperparathyroidism of experimental uremia is reversed by calcimimetics: correlation with post-translational modification of the trans acting factor AUF1. J Am Soc Nephrol (2006) 17:107-112.</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Lindberg J.S., Moe S.M., Goodman W.G., Coburn J.W., Sprague S.M., Liu W., Blaisdell P.W., Brenner R.M., Turner S.A., and Martin K.J. The calcimimetic AMG073 reduces parathyroid hormone and calcium x phosphorus in secondary hyperparathyroidism. Kidney Int 63: 248-254, 2003.</mixed-citation><mixed-citation xml:lang="en">Lindberg J.S., Moe S.M., Goodman W.G., Coburn J.W., Sprague S.M., Liu W., Blaisdell P.W., Brenner R.M., Turner S.A., and Martin K.J. The calcimimetic AMG073 reduces parathyroid hormone and calcium x phosphorus in secondary hyperparathyroidism. Kidney Int 63: 248-254, 2003.</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">Lopez-Barneo J., and Armstrong C.M. Depolarizing response of rat parathyroid cells to divalent cations. J Gen Physiol 82: 269-294, 1983.</mixed-citation><mixed-citation xml:lang="en">Lopez-Barneo J., and Armstrong C.M. Depolarizing response of rat parathyroid cells to divalent cations. J Gen Physiol 82: 269-294, 1983.</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Malluche H.H., Monier-Faugere M.C., Wang G., et al. Cinacalcet HCl reduces bone turnover and bone marrow fibrosis in hemodialisis patients with secondary hyperparathyroidism (HPT) [abstract # M016]. 41-st Congress of The European Renal Association and The European Dialisis And Transplant Association; 2004 May 15-18; Lisbon</mixed-citation><mixed-citation xml:lang="en">Malluche H.H., Monier-Faugere M.C., Wang G., et al. Cinacalcet HCl reduces bone turnover and bone marrow fibrosis in hemodialisis patients with secondary hyperparathyroidism (HPT) [abstract # M016]. 41-st Congress of The European Renal Association and The European Dialisis And Transplant Association; 2004 May 15-18; Lisbon</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">Martin-Salvago M., Villar-Rodriguez J.L., Palma-Alvarez A., Beato-Moreno A., and Galera-Davidson H. Decreased expression of calcium receptor in parathyroid tissue in patients with hyperparathyroidism secondary to chronic renal failure. Endocr Pathol 14: 61-70, 2003.</mixed-citation><mixed-citation xml:lang="en">Martin-Salvago M., Villar-Rodriguez J.L., Palma-Alvarez A., Beato-Moreno A., and Galera-Davidson H. Decreased expression of calcium receptor in parathyroid tissue in patients with hyperparathyroidism secondary to chronic renal failure. Endocr Pathol 14: 61-70, 2003.</mixed-citation></citation-alternatives></ref><ref id="cit57"><label>57</label><citation-alternatives><mixed-citation xml:lang="ru">Martin D., Miller G., Colloton M., Shatzen E., and Lacey D. Cinacalcet HCl decreases parathyroid hyperplasia in a rodent model of chronic renal insufficiency (CRI) (Abstract). J Am Soc Nephrol 14: 462A., 2003.</mixed-citation><mixed-citation xml:lang="en">Martin D., Miller G., Colloton M., Shatzen E., and Lacey D. Cinacalcet HCl decreases parathyroid hyperplasia in a rodent model of chronic renal insufficiency (CRI) (Abstract). J Am Soc Nephrol 14: 462A., 2003.</mixed-citation></citation-alternatives></ref><ref id="cit58"><label>58</label><citation-alternatives><mixed-citation xml:lang="ru">Moallem E., Kilav R., Silver J., and Naveh-Many T. RNA-protein binding and post-transcriptional regulation of parathyroid hormone gene expression by calcium and phosphate. J Biol Chem 273: 5253-5259, 1998.</mixed-citation><mixed-citation xml:lang="en">Moallem E., Kilav R., Silver J., and Naveh-Many T. RNA-protein binding and post-transcriptional regulation of parathyroid hormone gene expression by calcium and phosphate. J Biol Chem 273: 5253-5259, 1998.</mixed-citation></citation-alternatives></ref><ref id="cit59"><label>59</label><citation-alternatives><mixed-citation xml:lang="ru">Moe S.M., Cunningham J., Bommer J., et al. Long-term treatment of secondary hyperparathyroidism with the calcimimetic cinacalcet HCl. Nephrol Dial Transplant (2005) 20:2186-2193</mixed-citation><mixed-citation xml:lang="en">Moe S.M., Cunningham J., Bommer J., et al. Long-term treatment of secondary hyperparathyroidism with the calcimimetic cinacalcet HCl. Nephrol Dial Transplant (2005) 20:2186-2193</mixed-citation></citation-alternatives></ref><ref id="cit60"><label>60</label><citation-alternatives><mixed-citation xml:lang="ru">Moe S.M., Chen N.X. Pathophysiology of vascular calcification in chronic kidney disease Circ Res 95: 560-567, 2004</mixed-citation><mixed-citation xml:lang="en">Moe S.M., Chen N.X. Pathophysiology of vascular calcification in chronic kidney disease Circ Res 95: 560-567, 2004</mixed-citation></citation-alternatives></ref><ref id="cit61"><label>61</label><citation-alternatives><mixed-citation xml:lang="ru">Muff R., Nemeth E.F., Haller-Brem S., and Fischer J.A. Regulation of hormone secretion and cytosolic Ca2+ by extracellular Ca2+ in parathyroid cells and C-cells: role of voltage-sensitive Ca2+ channels. Arch Biochem Biophys 265: 128-135, 1988.</mixed-citation><mixed-citation xml:lang="en">Muff R., Nemeth E.F., Haller-Brem S., and Fischer J.A. Regulation of hormone secretion and cytosolic Ca2+ by extracellular Ca2+ in parathyroid cells and C-cells: role of voltage-sensitive Ca2+ channels. Arch Biochem Biophys 265: 128-135, 1988.</mixed-citation></citation-alternatives></ref><ref id="cit62"><label>62</label><citation-alternatives><mixed-citation xml:lang="ru">Nagano N., Nemeth E.F. Functional proteins involved in regulation of intracellular Ca(2+) for drug development: The extracellular calcium receptor and an innovative medical approach to control secondary hyperparathyroidism by calcimimetics. J Pharmacol Sci 2005;97 (3):355-60.</mixed-citation><mixed-citation xml:lang="en">Nagano N., Nemeth E.F. Functional proteins involved in regulation of intracellular Ca(2+) for drug development: The extracellular calcium receptor and an innovative medical approach to control secondary hyperparathyroidism by calcimimetics. J Pharmacol Sci 2005;97 (3):355-60.</mixed-citation></citation-alternatives></ref><ref id="cit63"><label>63</label><citation-alternatives><mixed-citation xml:lang="ru">National kidney foundation. K/DOQI Clinical Practice Guidelines for Bone Metabolism and Disease in Chronic Kidney disease 2003.</mixed-citation><mixed-citation xml:lang="en">National kidney foundation. K/DOQI Clinical Practice Guidelines for Bone Metabolism and Disease in Chronic Kidney disease 2003.</mixed-citation></citation-alternatives></ref><ref id="cit64"><label>64</label><citation-alternatives><mixed-citation xml:lang="ru">Nemeth E.F. and Scarpa A. Rapid mobilization of cellular Ca2+ in bovine parathyroid cells evoked by extracellular divalent cations. Evidence for a cell surface calcium receptor. J Biol Chem 262: 5188-5196, 1987.</mixed-citation><mixed-citation xml:lang="en">Nemeth E.F. and Scarpa A. Rapid mobilization of cellular Ca2+ in bovine parathyroid cells evoked by extracellular divalent cations. Evidence for a cell surface calcium receptor. J Biol Chem 262: 5188-5196, 1987.</mixed-citation></citation-alternatives></ref><ref id="cit65"><label>65</label><citation-alternatives><mixed-citation xml:lang="ru">Nemeth E.F., Steffey M.E., Hammerland L.G., Hung B.C., Van Wagenen B.C., DelMar E.G., and Balandrin M.F. Calcimimetics with potent and selective activity on the parathyroid calcium receptor. Proc Natl Acad Sci USA 95: 4040-4045, 1998.</mixed-citation><mixed-citation xml:lang="en">Nemeth E.F., Steffey M.E., Hammerland L.G., Hung B.C., Van Wagenen B.C., DelMar E.G., and Balandrin M.F. Calcimimetics with potent and selective activity on the parathyroid calcium receptor. Proc Natl Acad Sci USA 95: 4040-4045, 1998.</mixed-citation></citation-alternatives></ref><ref id="cit66"><label>66</label><citation-alternatives><mixed-citation xml:lang="ru">Nemeth E.F., Heaton W.H., Miller M., Fox J., Balandrin M.F., Van Wagenen B.C., Colloton M., Karbon W., Scherrer J., Shatzen E., Rishton G., Scully S., Qi M., Harris R., Lacey D., and Martin D. Pharmacodynamics of the type II calcimimetic compound cinacalcet HCl. J Pharmacol Exp Ther 308: 627-635, 2004.</mixed-citation><mixed-citation xml:lang="en">Nemeth E.F., Heaton W.H., Miller M., Fox J., Balandrin M.F., Van Wagenen B.C., Colloton M., Karbon W., Scherrer J., Shatzen E., Rishton G., Scully S., Qi M., Harris R., Lacey D., and Martin D. Pharmacodynamics of the type II calcimimetic compound cinacalcet HCl. J Pharmacol Exp Ther 308: 627-635, 2004.</mixed-citation></citation-alternatives></ref><ref id="cit67"><label>67</label><citation-alternatives><mixed-citation xml:lang="ru">Nemeth E.F., Steffey M.E. &amp;amp; Fox J. (1996). The parathyroid calcium receptor: a novel therapeutic target for treating hyperparathyroidism. Pediatric Nephrology, 10: 275-279</mixed-citation><mixed-citation xml:lang="en">Nemeth E.F., Steffey M.E. &amp;amp; Fox J. (1996). The parathyroid calcium receptor: a novel therapeutic target for treating hyperparathyroidism. Pediatric Nephrology, 10: 275-279</mixed-citation></citation-alternatives></ref><ref id="cit68"><label>68</label><citation-alternatives><mixed-citation xml:lang="ru">Nemeth E.F. Ca2+ receptor-dependent regulation of cellular functions. News Physiol Sci 10: 1-5, 1995.</mixed-citation><mixed-citation xml:lang="en">Nemeth E.F. Ca2+ receptor-dependent regulation of cellular functions. News Physiol Sci 10: 1-5, 1995.</mixed-citation></citation-alternatives></ref><ref id="cit69"><label>69</label><citation-alternatives><mixed-citation xml:lang="ru">Nemeth E.F. Calcium receptors as novel drug targets. In: Principles of Bone Biology (1st ed.), edited by Bilezikian J.P., Raisz L.G., and Rodan G.A. San Diego, CA: Academic, 1996, p. 1019-1035.</mixed-citation><mixed-citation xml:lang="en">Nemeth E.F. Calcium receptors as novel drug targets. In: Principles of Bone Biology (1st ed.), edited by Bilezikian J.P., Raisz L.G., and Rodan G.A. San Diego, CA: Academic, 1996, p. 1019-1035.</mixed-citation></citation-alternatives></ref><ref id="cit70"><label>70</label><citation-alternatives><mixed-citation xml:lang="ru">Odenwald T.R.E., Roesch F., Schaefer F., Schmitt C.P. The calcimimetic R568 lowers blood pressure, but not total body sodium content, in rats [Abstract]. J Am Soc Nephrol 15: 279a, 2004</mixed-citation><mixed-citation xml:lang="en">Odenwald T.R.E., Roesch F., Schaefer F., Schmitt C.P. The calcimimetic R568 lowers blood pressure, but not total body sodium content, in rats [Abstract]. J Am Soc Nephrol 15: 279a, 2004</mixed-citation></citation-alternatives></ref><ref id="cit71"><label>71</label><citation-alternatives><mixed-citation xml:lang="ru">Ohanian J., Gatfield K.M., Ward D.T., Ohanian V. Evidence for a functional calcium-sensing receptor that modulates myogenic tone in rat subcutaneous small arteries. Am J Physiol Heart Circ Physiol 288: H1756 -H1762, 2005</mixed-citation><mixed-citation xml:lang="en">Ohanian J., Gatfield K.M., Ward D.T., Ohanian V. Evidence for a functional calcium-sensing receptor that modulates myogenic tone in rat subcutaneous small arteries. Am J Physiol Heart Circ Physiol 288: H1756 -H1762, 2005</mixed-citation></citation-alternatives></ref><ref id="cit72"><label>72</label><citation-alternatives><mixed-citation xml:lang="ru">Owda A.K., Mousa D., Abdallah A.H., Hawas F.A., Al-Harbi W., Fedail H., At-Shoail G., Al-Sulaiman M.H., and Al-Khader A.A. Long-term intravenous calcitriol in secondary hyperparathyroidism: the role of technetium-99m-MIBI scintigraphy in predicting the response to treatment. Ren Fail 24: 165-173, 2002.</mixed-citation><mixed-citation xml:lang="en">Owda A.K., Mousa D., Abdallah A.H., Hawas F.A., Al-Harbi W., Fedail H., At-Shoail G., Al-Sulaiman M.H., and Al-Khader A.A. Long-term intravenous calcitriol in secondary hyperparathyroidism: the role of technetium-99m-MIBI scintigraphy in predicting the response to treatment. Ren Fail 24: 165-173, 2002.</mixed-citation></citation-alternatives></ref><ref id="cit73"><label>73</label><citation-alternatives><mixed-citation xml:lang="ru">Pearce S. Extracellular 'calcistat' in health and disease Lancet 1999; 353:83-4,</mixed-citation><mixed-citation xml:lang="en">Pearce S. Extracellular 'calcistat' in health and disease Lancet 1999; 353:83-4,</mixed-citation></citation-alternatives></ref><ref id="cit74"><label>74</label><citation-alternatives><mixed-citation xml:lang="ru">Peacock M., Bilezikian J.P., Preston S., et al. Cinacalcet HCl maintains long-term normocalcemia in patients with primary hyperparathyroidism [e-pub ahead of print]. J Clin Endo 2004 Nov 2</mixed-citation><mixed-citation xml:lang="en">Peacock M., Bilezikian J.P., Preston S., et al. Cinacalcet HCl maintains long-term normocalcemia in patients with primary hyperparathyroidism [e-pub ahead of print]. J Clin Endo 2004 Nov 2</mixed-citation></citation-alternatives></ref><ref id="cit75"><label>75</label><citation-alternatives><mixed-citation xml:lang="ru">Peacock M., Scumpia S., Bolognese M.A., et al. Long-term control of primary hyperparathyroidism with cinacalcet HCl (AMG 073) [abstract#1060] J Bone Miner Res 2003: 18 suppl. 2: S17</mixed-citation><mixed-citation xml:lang="en">Peacock M., Scumpia S., Bolognese M.A., et al. Long-term control of primary hyperparathyroidism with cinacalcet HCl (AMG 073) [abstract#1060] J Bone Miner Res 2003: 18 suppl. 2: S17</mixed-citation></citation-alternatives></ref><ref id="cit76"><label>76</label><citation-alternatives><mixed-citation xml:lang="ru">Pollak M.R., Brown E.M., Chou Y.H.W., Hebert S.C., Marx S.J., Steinman B., Levi T., Seidman C.E., and Seidman J.G. Mutations of the human Ca2+-sensing receptor gene causing familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. Cell 75: 1297-1303, 1993.</mixed-citation><mixed-citation xml:lang="en">Pollak M.R., Brown E.M., Chou Y.H.W., Hebert S.C., Marx S.J., Steinman B., Levi T., Seidman C.E., and Seidman J.G. Mutations of the human Ca2+-sensing receptor gene causing familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. Cell 75: 1297-1303, 1993.</mixed-citation></citation-alternatives></ref><ref id="cit77"><label>77</label><citation-alternatives><mixed-citation xml:lang="ru">Pollak M.R., Brown E.M., Estep H.L., McLaine P.N., Kifor O., Park J., Hebert S.C., Seidman C.E., and Seidman J.G. Autosomal dominant hypocalcaemia caused by a Ca2+-sensing receptor gene mutation. Nat Genet 8: 303-307, 1994.</mixed-citation><mixed-citation xml:lang="en">Pollak M.R., Brown E.M., Estep H.L., McLaine P.N., Kifor O., Park J., Hebert S.C., Seidman C.E., and Seidman J.G. Autosomal dominant hypocalcaemia caused by a Ca2+-sensing receptor gene mutation. Nat Genet 8: 303-307, 1994.</mixed-citation></citation-alternatives></ref><ref id="cit78"><label>78</label><citation-alternatives><mixed-citation xml:lang="ru">Pollak M.R., Chou Y.H., Marx S.J., Steinmann B., Cole D.E., Brandi M.L., Papapoulos S.E., Menko F.H., Hendy G.N., and Brown E.M. familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. Effects of mutant gene dosage on phenotype. J Clin Invest 93: 1108-1112, 1994.</mixed-citation><mixed-citation xml:lang="en">Pollak M.R., Chou Y.H., Marx S.J., Steinmann B., Cole D.E., Brandi M.L., Papapoulos S.E., Menko F.H., Hendy G.N., and Brown E.M. familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. Effects of mutant gene dosage on phenotype. J Clin Invest 93: 1108-1112, 1994.</mixed-citation></citation-alternatives></ref><ref id="cit79"><label>79</label><citation-alternatives><mixed-citation xml:lang="ru">Raine A.E., Margreiter R., Brunner F.P., Ehrich J.H., Geerlings W., Landais P., Loirat C., Mallick N.P., Selwood N.H., Tufveson G., et al. Report on management of renal failure in Europe, XXII, 1991. Nephrol Dial Transplant 7[Suppl 2]: 7-35, 1992 1</mixed-citation><mixed-citation xml:lang="en">Raine A.E., Margreiter R., Brunner F.P., Ehrich J.H., Geerlings W., Landais P., Loirat C., Mallick N.P., Selwood N.H., Tufveson G., et al. Report on management of renal failure in Europe, XXII, 1991. Nephrol Dial Transplant 7[Suppl 2]: 7-35, 1992 1</mixed-citation></citation-alternatives></ref><ref id="cit80"><label>80</label><citation-alternatives><mixed-citation xml:lang="ru">Reichel H., Deibert B., Schmidt-Gayk H., Ritz E. Calcium metabolism in early chronic renal failure: Implications for the pathogenesis of hyperparathyroidism. Nephrol Dial Transplant 1991; 6: 162-169.</mixed-citation><mixed-citation xml:lang="en">Reichel H., Deibert B., Schmidt-Gayk H., Ritz E. Calcium metabolism in early chronic renal failure: Implications for the pathogenesis of hyperparathyroidism. Nephrol Dial Transplant 1991; 6: 162-169.</mixed-citation></citation-alternatives></ref><ref id="cit81"><label>81</label><citation-alternatives><mixed-citation xml:lang="ru">Rodriguez M., Caravaca F., Fernandez E., Borrego M.J., Lorenzo V., Cubero J., Martin-Malo A., Betriu A., Jimenez A., Torres A., and Felsenfeld A.J. Parathyroid function as a determinant of the response to calcitriol treatment in the hemodialysis patient. Kidney Int 56: 306-317, 1999.</mixed-citation><mixed-citation xml:lang="en">Rodriguez M., Caravaca F., Fernandez E., Borrego M.J., Lorenzo V., Cubero J., Martin-Malo A., Betriu A., Jimenez A., Torres A., and Felsenfeld A.J. Parathyroid function as a determinant of the response to calcitriol treatment in the hemodialysis patient. Kidney Int 56: 306-317, 1999.</mixed-citation></citation-alternatives></ref><ref id="cit82"><label>82</label><citation-alternatives><mixed-citation xml:lang="ru">Russell J., Bar A., Sheamgenood L.M., and Huamgenitz S. Interaction between calcium and 1,25-dihydroxyvitamin D3 in the regulation of preproparathyroid hormone and vitamin D receptor messenger ribonucleic acid in avian parathyroids. Endocrinology 132: 2639-2644, 1993. 394</mixed-citation><mixed-citation xml:lang="en">Russell J., Bar A., Sheamgenood L.M., and Huamgenitz S. Interaction between calcium and 1,25-dihydroxyvitamin D3 in the regulation of preproparathyroid hormone and vitamin D receptor messenger ribonucleic acid in avian parathyroids. Endocrinology 132: 2639-2644, 1993. 394</mixed-citation></citation-alternatives></ref><ref id="cit83"><label>83</label><citation-alternatives><mixed-citation xml:lang="ru">Russell J., Lettieri D.F., and Sheamgenood L.M. Direct regulation by calcium of cytoplasmic messenger ribonucleic acid coding for preproparathyroid hormone in isolated bovine parathyroid cells. J Clin Invest 72: 1851-1855, 1983.</mixed-citation><mixed-citation xml:lang="en">Russell J., Lettieri D.F., and Sheamgenood L.M. Direct regulation by calcium of cytoplasmic messenger ribonucleic acid coding for preproparathyroid hormone in isolated bovine parathyroid cells. J Clin Invest 72: 1851-1855, 1983.</mixed-citation></citation-alternatives></ref><ref id="cit84"><label>84</label><citation-alternatives><mixed-citation xml:lang="ru">Serra A.L., Savoca R., Huber A.R., Hepp U., Delsignore A., Hersberger M., Wüthrich R.P. Effective control of persistent hyperparathyroidism with cinacalcet in renal allograft recipients: Nephrol Dial Transplant. 2007 Feb;22 (2):577-83</mixed-citation><mixed-citation xml:lang="en">Serra A.L., Savoca R., Huber A.R., Hepp U., Delsignore A., Hersberger M., Wüthrich R.P. Effective control of persistent hyperparathyroidism with cinacalcet in renal allograft recipients: Nephrol Dial Transplant. 2007 Feb;22 (2):577-83</mixed-citation></citation-alternatives></ref><ref id="cit85"><label>85</label><citation-alternatives><mixed-citation xml:lang="ru">Shane E. Clinical review 122: Parathyroid Carcinoma. J Clin Endocrin Metab 2001; 86 (2): 485-93</mixed-citation><mixed-citation xml:lang="en">Shane E. Clinical review 122: Parathyroid Carcinoma. J Clin Endocrin Metab 2001; 86 (2): 485-93</mixed-citation></citation-alternatives></ref><ref id="cit86"><label>86</label><citation-alternatives><mixed-citation xml:lang="ru">Silver J., Moallem E., Kilav R., Epstein E., Sela A., and Naveh-Many T. New insights into the regulation of parathyroid hormone synthesis and secretion in chronic renal failure. Nephrol Dial Transplant 11: 2-5, 1996.</mixed-citation><mixed-citation xml:lang="en">Silver J., Moallem E., Kilav R., Epstein E., Sela A., and Naveh-Many T. New insights into the regulation of parathyroid hormone synthesis and secretion in chronic renal failure. Nephrol Dial Transplant 11: 2-5, 1996.</mixed-citation></citation-alternatives></ref><ref id="cit87"><label>87</label><citation-alternatives><mixed-citation xml:lang="ru">Silverberg S.J., Bone H.G. III, Marriott T.B., Locker F.G., Thys-Jacobs S., Dziem G., Kaatz S., Sanguinetti E.L., and Bilezikian J.P. Short-term inhibition of parathyroid hormone secretion by a calcium-receptor agonist in patients with primary hyperparathyroidism. N Engl J Med 337: 1506-1510, 1997.</mixed-citation><mixed-citation xml:lang="en">Silverberg S.J., Bone H.G. III, Marriott T.B., Locker F.G., Thys-Jacobs S., Dziem G., Kaatz S., Sanguinetti E.L., and Bilezikian J.P. Short-term inhibition of parathyroid hormone secretion by a calcium-receptor agonist in patients with primary hyperparathyroidism. N Engl J Med 337: 1506-1510, 1997.</mixed-citation></citation-alternatives></ref><ref id="cit88"><label>88</label><citation-alternatives><mixed-citation xml:lang="ru">Silverberg S.J., Fairman C., Bilezikian J.P., et al. The effects of cinacalcet HCl (AMG073) on serum alcium levels in patients with parathyroid carcinoma or recurrent primary HPT after PTx [abstract#SA-420] J Bone Miner Res 2003; 18 suppl. 2: s171</mixed-citation><mixed-citation xml:lang="en">Silverberg S.J., Fairman C., Bilezikian J.P., et al. The effects of cinacalcet HCl (AMG073) on serum alcium levels in patients with parathyroid carcinoma or recurrent primary HPT after PTx [abstract#SA-420] J Bone Miner Res 2003; 18 suppl. 2: s171</mixed-citation></citation-alternatives></ref><ref id="cit89"><label>89</label><citation-alternatives><mixed-citation xml:lang="ru">Smogorzewski M., Perna A.F., Borum P.R., Massry S.G. Fatty acid oxidation in the myocardium: Effects of parathyroid hormone and CRF. Kidney Int 34: 797-803, 1988 16</mixed-citation><mixed-citation xml:lang="en">Smogorzewski M., Perna A.F., Borum P.R., Massry S.G. Fatty acid oxidation in the myocardium: Effects of parathyroid hormone and CRF. Kidney Int 34: 797-803, 1988 16</mixed-citation></citation-alternatives></ref><ref id="cit90"><label>90</label><citation-alternatives><mixed-citation xml:lang="ru">Stefenelli T., Abela C., Frank H., Koller-Strametz J., Globits S., Bergler-Klein J., Niederle B. Cardiac abnormalities in patients with primary hyperparathyroidism: Implications for follow-up. J Clin Endocrinol Metab 82: 106-112, 1997</mixed-citation><mixed-citation xml:lang="en">Stefenelli T., Abela C., Frank H., Koller-Strametz J., Globits S., Bergler-Klein J., Niederle B. Cardiac abnormalities in patients with primary hyperparathyroidism: Implications for follow-up. J Clin Endocrinol Metab 82: 106-112, 1997</mixed-citation></citation-alternatives></ref><ref id="cit91"><label>91</label><citation-alternatives><mixed-citation xml:lang="ru">Strippoli G.F., Palmer S., Tong A., Elder G., Messa P., Craig J.C. Meta-analysis of biochemical and patient-level effects of calcimimetic therapy. Am J Kidney Dis. 2006 May;47 (5):715-26.]</mixed-citation><mixed-citation xml:lang="en">Strippoli G.F., Palmer S., Tong A., Elder G., Messa P., Craig J.C. Meta-analysis of biochemical and patient-level effects of calcimimetic therapy. Am J Kidney Dis. 2006 May;47 (5):715-26.]</mixed-citation></citation-alternatives></ref><ref id="cit92"><label>92</label><citation-alternatives><mixed-citation xml:lang="ru">Torres P.U. Cinacalcet HCl: a novel treatment for secondary hyperparathyroidism caused by chronic kidney disease J Ren Nutr. 2006 Jul;16 (3):253-8.]</mixed-citation><mixed-citation xml:lang="en">Torres P.U. Cinacalcet HCl: a novel treatment for secondary hyperparathyroidism caused by chronic kidney disease J Ren Nutr. 2006 Jul;16 (3):253-8.]</mixed-citation></citation-alternatives></ref><ref id="cit93"><label>93</label><citation-alternatives><mixed-citation xml:lang="ru">Wada M., Furuya Y., Kobayashi N., Kobayashi N., Miyata S., Ishii H., and Nagano N. The calcimimetic compound AMG 073 (cinacalcet HCl) Ameliorates osteitis fibrosa in rats with chronic renal insufficiency. J Am Soc Nephrol 14: 48A (abstract SU-FC218), 2003.</mixed-citation><mixed-citation xml:lang="en">Wada M., Furuya Y., Kobayashi N., Kobayashi N., Miyata S., Ishii H., and Nagano N. The calcimimetic compound AMG 073 (cinacalcet HCl) Ameliorates osteitis fibrosa in rats with chronic renal insufficiency. J Am Soc Nephrol 14: 48A (abstract SU-FC218), 2003.</mixed-citation></citation-alternatives></ref><ref id="cit94"><label>94</label><citation-alternatives><mixed-citation xml:lang="ru">Wada M., Furuya Y., Sakiyama J., Kobayashi N., Miyata S., Ishii H., and Nagano N. The calcimimetic compound NPS R-568 suppresses parathyroid cell proliferation in rats with renal insufficiency. Control of parathyroid cell growth via a calcium receptor. J Clin Invest 100: 2977-2983, 1997.</mixed-citation><mixed-citation xml:lang="en">Wada M., Furuya Y., Sakiyama J., Kobayashi N., Miyata S., Ishii H., and Nagano N. The calcimimetic compound NPS R-568 suppresses parathyroid cell proliferation in rats with renal insufficiency. Control of parathyroid cell growth via a calcium receptor. J Clin Invest 100: 2977-2983, 1997.</mixed-citation></citation-alternatives></ref><ref id="cit95"><label>95</label><citation-alternatives><mixed-citation xml:lang="ru">Wada M., Ishii H., Furuya Y., Fox J., Nemeth E.F., Nagano N. NPS R-568 halts or reverses osteitis fibrosa in uremic rats. Kidney Int (1998) 53:448-453.</mixed-citation><mixed-citation xml:lang="en">Wada M., Ishii H., Furuya Y., Fox J., Nemeth E.F., Nagano N. NPS R-568 halts or reverses osteitis fibrosa in uremic rats. Kidney Int (1998) 53:448-453.</mixed-citation></citation-alternatives></ref><ref id="cit96"><label>96</label><citation-alternatives><mixed-citation xml:lang="ru">Wada M., Nagano N., Furuya Y., Chin J., Nemeth E.F., and Fox J. Calcimimetic NPS R-568 prevents parathyroid hyperplasia in rats with severe secondary hyperparathyroidism. Kidney Int 57: 50-58, 2000.</mixed-citation><mixed-citation xml:lang="en">Wada M., Nagano N., Furuya Y., Chin J., Nemeth E.F., and Fox J. Calcimimetic NPS R-568 prevents parathyroid hyperplasia in rats with severe secondary hyperparathyroidism. Kidney Int 57: 50-58, 2000.</mixed-citation></citation-alternatives></ref><ref id="cit97"><label>97</label><citation-alternatives><mixed-citation xml:lang="ru">Wada M., Nagano N., Nemeth E.F. The calcium receptor and calcimimetics. Curr Opin Nephrol Hypertens 8: 429-433, 1999</mixed-citation><mixed-citation xml:lang="en">Wada M., Nagano N., Nemeth E.F. The calcium receptor and calcimimetics. Curr Opin Nephrol Hypertens 8: 429-433, 1999</mixed-citation></citation-alternatives></ref><ref id="cit98"><label>98</label><citation-alternatives><mixed-citation xml:lang="ru">Watts. R. W. E. Idiopathic urinary stone disease: possible polygenic aetiological factors. QJM 2005 98 (4):241-246; doi:10.1093/ 041).</mixed-citation><mixed-citation xml:lang="en">Watts. R. W. E. Idiopathic urinary stone disease: possible polygenic aetiological factors. QJM 2005 98 (4):241-246; doi:10.1093/ 041).</mixed-citation></citation-alternatives></ref><ref id="cit99"><label>99</label><citation-alternatives><mixed-citation xml:lang="ru">Quarles L.D., Sherrard D.J., Adler S., Rosansky S.J., Mc-Cary L.C., Liu W., Turner S.A., and Bushinsky D.A. The calcimimetic AMG 073 as a potential treatment for secondary hyperparathyroidism of end-stage renal disease J Am Soc Nephrol 14: 1710-1721, 2003.</mixed-citation><mixed-citation xml:lang="en">Quarles L.D., Sherrard D.J., Adler S., Rosansky S.J., Mc-Cary L.C., Liu W., Turner S.A., and Bushinsky D.A. The calcimimetic AMG 073 as a potential treatment for secondary hyperparathyroidism of end-stage renal disease J Am Soc Nephrol 14: 1710-1721, 2003.</mixed-citation></citation-alternatives></ref><ref id="cit100"><label>100</label><citation-alternatives><mixed-citation xml:lang="ru">Quarles L.D., Spiegel D. M., Qurzi M. et al. The effects of 1-year treatment with the calcimimetic AMG073 and bone health in ESRD patients with secondary hyperparathyroidism (SHPT) [abstract # SU-P0510. J Am Soc Nefrol 2002; 13 suppl.:572A</mixed-citation><mixed-citation xml:lang="en">Quarles L.D., Spiegel D. M., Qurzi M. et al. The effects of 1-year treatment with the calcimimetic AMG073 and bone health in ESRD patients with secondary hyperparathyroidism (SHPT) [abstract # SU-P0510. J Am Soc Nefrol 2002; 13 suppl.:572A</mixed-citation></citation-alternatives></ref><ref id="cit101"><label>101</label><citation-alternatives><mixed-citation xml:lang="ru">Quinn S.J., Kifor O., Trivedi S., Diaz R., Vassilev P., Brown E. Sodium and ionic strength sensing by the calcium receptor. J Biol Chem 1998;273 (31):19579-86.</mixed-citation><mixed-citation xml:lang="en">Quinn S.J., Kifor O., Trivedi S., Diaz R., Vassilev P., Brown E. Sodium and ionic strength sensing by the calcium receptor. J Biol Chem 1998;273 (31):19579-86.</mixed-citation></citation-alternatives></ref><ref id="cit102"><label>102</label><citation-alternatives><mixed-citation xml:lang="ru">Yamamoto M., Igarishi T., Muramatsu M., Fukagawa M., Motokura T., and Ogata E. Hypocalcemia increases and hypercalcemia decreases the steady state level of parathyroid hormone messenger RNA in the rat. J Clin Invest 83: 1053-1056, 1989.</mixed-citation><mixed-citation xml:lang="en">Yamamoto M., Igarishi T., Muramatsu M., Fukagawa M., Motokura T., and Ogata E. Hypocalcemia increases and hypercalcemia decreases the steady state level of parathyroid hormone messenger RNA in the rat. J Clin Invest 83: 1053-1056, 1989.</mixed-citation></citation-alternatives></ref><ref id="cit103"><label>103</label><citation-alternatives><mixed-citation xml:lang="ru">Yano S., Sugimoto T., Tsukamoto T., Chihara K., Kobayashi A., Kitazawa S., Maeda S., and Kitazawa R. Decrease in vitamin D receptor and calcium-sensing receptor in highly proliferative parathyroid adenomas. Eur J Endocrinol 148: 403-411, 2003.</mixed-citation><mixed-citation xml:lang="en">Yano S., Sugimoto T., Tsukamoto T., Chihara K., Kobayashi A., Kitazawa S., Maeda S., and Kitazawa R. Decrease in vitamin D receptor and calcium-sensing receptor in highly proliferative parathyroid adenomas. Eur J Endocrinol 148: 403-411, 2003.</mixed-citation></citation-alternatives></ref><ref id="cit104"><label>104</label><citation-alternatives><mixed-citation xml:lang="ru">Хори Б., Дрюке Т. Взаимосвязь паращитовидных желез и костной ткани в условиях уремии: новое понимание старой проблемы. В книге: "Cовременные аспекты заместительной терапии при почечной недостаточности". Cборник материалов международного нефрологического симпозиума. 8-9 сентября 1998 г., Москва, Россия, стр. 32-37.</mixed-citation><mixed-citation xml:lang="en">Хори Б., Дрюке Т. Взаимосвязь паращитовидных желез и костной ткани в условиях уремии: новое понимание старой проблемы. В книге: "Cовременные аспекты заместительной терапии при почечной недостаточности". Cборник материалов международного нефрологического симпозиума. 8-9 сентября 1998 г., Москва, Россия, стр. 32-37.</mixed-citation></citation-alternatives></ref><ref id="cit105"><label>105</label><citation-alternatives><mixed-citation xml:lang="ru">Amgen Inc Eureopean Comision approves innovative first-in-class treatment for serious complications of chronic kidney disease [online]. Available from URL: http://www.amgen. com [Accessed 2004 Nov 1]</mixed-citation><mixed-citation xml:lang="en">Amgen Inc Eureopean Comision approves innovative first-in-class treatment for serious complications of chronic kidney disease [online]. Available from URL: http://www.amgen. com [Accessed 2004 Nov 1]</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
