porozendoОстеопороз и остеопатииOsteoporosis and Bone Diseases2072-26802311-0716Endocrinology Research Centre10.14341/osteo2014327-30porozendo-8892Research ArticleСтатьиArticlesРОЛЬ ВИТАМИНА D В ПАТОГЕНЕЗЕ ХРОНИЧЕСКИХ НЕИНФЕКЦИОННЫХ ЗАБОЛЕВАНИЙTHE ROLE OF VITAMIN D IN THE PATHOGENESIS OF CHRONIC NON-COMMUNICABLE DISEASESЕгшатянЛ ВEgshatyanL V

кандидат медицинских наук, научный сотрудник отдела изучения процессов старения и профилактики возрастассоциированных заболеваний

-ДудинскаяЕ НDudinskayaE N

кандидат медицинских наук, ведущий научный сотрудник отдела изучения процессов старения и профилактики возрастассоциированных заболеваний

-ТкачеваО НTkachevaO N

доктор медицинских наук, профессор, первый заместитель директора по научной и лечебной работе

-КаштановаД АKashtanovaD A

аспирант отдела изучения процессов старения и профилактики возраст-ассоциированных заболеваний

-Федеральное государственное бюджетное учреждение «Государственный научно-исследовательский центр профилактической медицины» Министерства здравоохранения Российской ФедерацииФГБУ ГНИЦПМ201415122014173№3 (2014)2730Copyright © Егшатян Л.В., Дудинская Е.Н., Ткачева О.Н., Каштанова Д.А., 20142014Егшатян Л.В., Дудинская Е.Н., Ткачева О.Н., Каштанова Д.А.Egshatyan L.V., Dudinskaya E.N., Tkacheva O.N., Kashtanova D.A.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.osteo-endojournals.ru/jour/article/view/8892

Представленный обзор демонстрирует роль витамина D не только в регуляции уровня кальция, но и в патогенезе хронического системного воспаления, нарушении инсулиночувствительности тканей к инсулину, его достаточное содержание в крови может привести к снижению риска развития СД 2 типа, ожирения, также аутоиммунной деструкции β-клеток поджелудочной железы и некоторых кардиометаболических факторов риска и сердечно-сосудистых заболеваний. Возможно, препараты витамина D в ближайшем будущем могут стать дополнительными и необходимыми веществами в коррекции ИР, хронического воспаления и в профилактике нарушений углеводного обмена и ССЗ.

This review shows the role of vitamin D in the regulation of not only the level of calcium, but also in the pathogenesis of chronic systemic inflammation, disruption of insulin sensitivity of tissues. The sufficient levels of vitamin D in the blood can lead to reduced risk of developing type 2 diabetes, obesity, autoimmune destruction of pancreatic β-cells, certain cardiometa-bolic risk factors, and therefore cardiovascular disease. Perhaps preparations of vitamin D in the near future may become additional and necessary nutritional substances for correction of insulin resistance, cardiovascular disease, chronic inflammation and prevention of disorders of glucose metabolism.

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The authors declare that there are no conflicts of interest present.