<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">porozendo</journal-id><journal-title-group><journal-title xml:lang="ru">Остеопороз и остеопатии</journal-title><trans-title-group xml:lang="en"><trans-title>Osteoporosis and Bone Diseases</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2072-2680</issn><issn pub-type="epub">2311-0716</issn><publisher><publisher-name>Endocrinology Research Centre</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.14341/osteo2016328-36</article-id><article-id custom-type="elpub" pub-id-type="custom">porozendo-9205</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>Articles</subject></subj-group></article-categories><title-group><article-title>КРАТКОЕ ИЗЛОЖЕНИЕ КЛИНИЧЕСКИХ РЕКОМЕНДАЦИЙ ПО ДИАГНОСТИКЕ И ЛЕЧЕНИЮ ОСТЕОПОРОЗА РОССИЙСКОЙ АССОЦИАЦИИ ЭНДОКРИНОЛОГОВ</article-title><trans-title-group xml:lang="en"><trans-title>SUMMARY OF CLINICAL GUIDELINES FOR THE DIAGNOSIS AND TREATMENT OF OSTEOPOROSIS OF THE RUSSIAN ASSOCIATION OF ENDOCRINOLOGISTS</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мельниченко</surname><given-names>Г А</given-names></name><name name-style="western" xml:lang="en"><surname>Melnichenko</surname><given-names>G A</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Белая</surname><given-names>Ж Е</given-names></name><name name-style="western" xml:lang="en"><surname>Belaya</surname><given-names>Zh E</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рожинская</surname><given-names>Л Я</given-names></name><name name-style="western" xml:lang="en"><surname>Rozhinskaya</surname><given-names>L Ya</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гребенникова</surname><given-names>Т А</given-names></name><name name-style="western" xml:lang="en"><surname>Grebennikova</surname><given-names>T A</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пигарова</surname><given-names>Е А</given-names></name><name name-style="western" xml:lang="en"><surname>Pigarova</surname><given-names>E A</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Торопцова</surname><given-names>Н В</given-names></name><name name-style="western" xml:lang="en"><surname>Toroptsova</surname><given-names>N V</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никитинская</surname><given-names>О А</given-names></name><name name-style="western" xml:lang="en"><surname>Nikitinskaya</surname><given-names>O A</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Фарба</surname><given-names>Л Я</given-names></name><name name-style="western" xml:lang="en"><surname>Farba</surname><given-names>L Ya</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарбаева</surname><given-names>Н В</given-names></name><name name-style="western" xml:lang="en"><surname>Tarbaeva</surname><given-names>N V</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чернова</surname><given-names>Т О</given-names></name><name name-style="western" xml:lang="en"><surname>Chernova</surname><given-names>T O</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дзеранова</surname><given-names>Л К</given-names></name><name name-style="western" xml:lang="en"><surname>Dzeranova</surname><given-names>L K</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ильин</surname><given-names>А В</given-names></name><name name-style="western" xml:lang="en"><surname>Ilyin</surname><given-names>A V</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юренева</surname><given-names>С В</given-names></name><name name-style="western" xml:lang="en"><surname>Yureneva</surname><given-names>S V</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Крюкова</surname><given-names>И В</given-names></name><name name-style="western" xml:lang="en"><surname>Kryukova</surname><given-names>I V</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мамедова</surname><given-names>Е О</given-names></name><name name-style="western" xml:lang="en"><surname>Mamedova</surname><given-names>E O</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бирюкова</surname><given-names>Е В</given-names></name><name name-style="western" xml:lang="en"><surname>Biryukova</surname><given-names>E V</given-names></name></name-alternatives><bio xml:lang="ru"><p>кафедра эндокринологии и диабетологии</p></bio><bio xml:lang="en"/><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-6"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Загородний</surname><given-names>Н В</given-names></name><name name-style="western" xml:lang="en"><surname>Zagorodny</surname><given-names>N V</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-7"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Родионова</surname><given-names>С С</given-names></name><name name-style="western" xml:lang="en"><surname>Rodionova</surname><given-names>S S</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-7"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лесняк</surname><given-names>О М</given-names></name><name name-style="western" xml:lang="en"><surname>Lesniak</surname><given-names>O M</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-8"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Скрипникова</surname><given-names>И А</given-names></name><name name-style="western" xml:lang="en"><surname>Skripnikova</surname><given-names>I A</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-9"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Древаль</surname><given-names>А В</given-names></name><name name-style="western" xml:lang="en"><surname>Dreval</surname><given-names>A V</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексеева</surname><given-names>Л А</given-names></name><name name-style="western" xml:lang="en"><surname>Alekseeva</surname><given-names>L A</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Дедов</surname><given-names>И И</given-names></name><name name-style="western" xml:lang="en"><surname>Dedov</surname><given-names>I I</given-names></name></name-alternatives><bio xml:lang="ru"/><bio xml:lang="en"/><email xlink:type="simple">-</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">ФГБУ «Эндокринологический научный центр» Минздрава России</aff><aff xml:lang="en"></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">ФГБНУ Научно-исследовательский институт ревматологии им. В.А. Насоновой</aff><aff xml:lang="en"></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">ГБУЗ Городская клиническая больница № 13, ДЗМ</aff><aff xml:lang="en"></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru">ФГБУ Научный центр акушерства, гинекологии и перинатологии Минздрава России им. В.И. Кулакова</aff><aff xml:lang="en"></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru">ГБУЗ МО Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского</aff><aff xml:lang="en"></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru">ФГБОУ Московский государственный медицинский стоматологический университет им. А.И. Евдокимова</aff><aff xml:lang="en"></aff></aff-alternatives><aff-alternatives id="aff-7"><aff xml:lang="ru">ФГБУ Центральный научно-клинический институт травматологии и ортопедии им. Н.Н. Приорова Минздрава России</aff><aff xml:lang="en"></aff></aff-alternatives><aff-alternatives id="aff-8"><aff xml:lang="ru">ФГБОУ ВО Северо-западный государственный медицинский университет им. И.И. Мечникова Минздрава России</aff><aff xml:lang="en"></aff></aff-alternatives><aff-alternatives id="aff-9"><aff xml:lang="ru">ФГБУ Государственный научно-исследовательский центр профилактической медицины Минздрава России</aff><aff xml:lang="en"></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>15</day><month>12</month><year>2016</year></pub-date><volume>19</volume><issue>3</issue><issue-title>№3 (2016)</issue-title><fpage>28</fpage><lpage>36</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Мельниченко Г.А., Белая Ж.Е., Рожинская Л.Я., Гребенникова Т.А., Пигарова Е.А., Торопцова Н.В., Никитинская О.А., Фарба Л.Я., Тарбаева Н.В., Чернова Т.О., Дзеранова Л.К., Ильин А.В., Юренева С.В., Крюкова И.В., Мамедова Е.О., Бирюкова Е.В., Загородний Н.В., Родионова С.С., Лесняк О.М., Скрипникова И.А., Древаль А.В., Алексеева Л.А., Дедов И.И., 2016</copyright-statement><copyright-year>2016</copyright-year><copyright-holder xml:lang="ru">Мельниченко Г.А., Белая Ж.Е., Рожинская Л.Я., Гребенникова Т.А., Пигарова Е.А., Торопцова Н.В., Никитинская О.А., Фарба Л.Я., Тарбаева Н.В., Чернова Т.О., Дзеранова Л.К., Ильин А.В., Юренева С.В., Крюкова И.В., Мамедова Е.О., Бирюкова Е.В., Загородний Н.В., Родионова С.С., Лесняк О.М., Скрипникова И.А., Древаль А.В., Алексеева Л.А., Дедов И.И.</copyright-holder><copyright-holder xml:lang="en">Melnichenko G.A., Belaya Z.E., Rozhinskaya L.Y., Grebennikova T.A., Pigarova E.A., Toroptsova N.V., Nikitinskaya O.A., Farba L.Y., Tarbaeva N.V., Chernova T.O., Dzeranova L.K., Ilyin A.V., Yureneva S.V., Kryukova I.V., Mamedova E.O., Biryukova E.V., Zagorodny N.V., Rodionova S.S., Lesniak O.M., Skripnikova I.A., Dreval A.V., Alekseeva L.A., Dedov I.I.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.osteo-endojournals.ru/jour/article/view/9205">https://www.osteo-endojournals.ru/jour/article/view/9205</self-uri><abstract><p>Представлено краткое изложение клинических рекомендаций по диагностике и лечению остеопороза, разработанных членами Российской ассоциации эндокринологов при участии членов Российской ассоциации по остеопорозу (ревматологов, травматологов, терапевтов, гинекологов-эндокринологов). Рекомендации разработаны с позиций доказательной медицины, в соответствии с требованиями к составлению клинических рекомендаций Минздрава России, опубликованными в 2016 г. Значительное место в изложении отведено диагностике остеопороза у взрослых, дифференциальной диагностике с другими метаболическими заболеваниями скелета, а также принципам патогенетического лечения остеопороза. Клинические рекомендации полезны будут как врачам общей практики, так и специалистам, прежде всего эндокринологам, ревматологам, травматологам-ортопедам, гинекологам, нефрологам, гастроэнднрологам и неврологам, так как остеопороз является мультифакториальным и мультидисциплинарным заболеванием</p></abstract></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kanis J.A., on behalf of the WHO Scientific Group. Assessment of osteoporosis at the primary health-care level. Technical Report. WHO Collaboraiting Centre, University of Sheffield, UK, 2008.</mixed-citation><mixed-citation xml:lang="en">Kanis J.A., on behalf of the WHO Scientific Group. Assessment of osteoporosis at the primary health-care level. Technical Report. WHO Collaboraiting Centre, University of Sheffield, UK, 2008.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Евстигнеева Л.П., Солодовников А.Г., Ершова О.Б., Белова К.Ю., Зоткин Е.Г., Чернова Т.О., Смирнов А.В., Скрипникова И.А., Поддубская Е.А., Косматова О.В., Новиков В.Е., Смирнов А.В., Ермакова И.П., Пронченко И.А., Зоткин Е.Г., Торопцова Н.В., Баранова И.А., Аникин С.Г., Марченкова Л.А., Крюкова ИВ, Зазерская И.Е., Коновалова В.Н., Кузнецова Л.В., Сметник В.П., Юренева С.В., Белая Ж.Е., Рожинская Л.Я., Баранова И.А., Дыдыкина И.С., Лесняк О.М., Беневоленская Л.И. Остеопороз. Диагностика, профилактика и лечение Москва, 2010. Клинические рекомендации (Второе издание, переработанное и дополненное).</mixed-citation><mixed-citation xml:lang="en">Евстигнеева Л.П., Солодовников А.Г., Ершова О.Б., Белова К.Ю., Зоткин Е.Г., Чернова Т.О., Смирнов А.В., Скрипникова И.А., Поддубская Е.А., Косматова О.В., Новиков В.Е., Смирнов А.В., Ермакова И.П., Пронченко И.А., Зоткин Е.Г., Торопцова Н.В., Баранова И.А., Аникин С.Г., Марченкова Л.А., Крюкова ИВ, Зазерская И.Е., Коновалова В.Н., Кузнецова Л.В., Сметник В.П., Юренева С.В., Белая Ж.Е., Рожинская Л.Я., Баранова И.А., Дыдыкина И.С., Лесняк О.М., Беневоленская Л.И. Остеопороз. Диагностика, профилактика и лечение Москва, 2010. Клинические рекомендации (Второе издание, переработанное и дополненное).</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Camacho P.M., Petak S.M., Binkley N., Clarke B.L., Harris S.T., Hurley D.L., Kleerekoper M., Lewiecki E.M., Miller P.D., Narula H.S., Pessah-Pollack R., Tangpricha V., Wimalawansa S.J., Watts N.B.: American association of clinical endocrinologists and American college of endocrinology clinical practice guidelines for the diagnosis and treatment of postmenopausal osteoporosis - 2016.Endocr Pract. 2016 Sep 2; 22(Suppl 4): 1-42.</mixed-citation><mixed-citation xml:lang="en">Camacho P.M., Petak S.M., Binkley N., Clarke B.L., Harris S.T., Hurley D.L., Kleerekoper M., Lewiecki E.M., Miller P.D., Narula H.S., Pessah-Pollack R., Tangpricha V., Wimalawansa S.J., Watts N.B.: American association of clinical endocrinologists and American college of endocrinology clinical practice guidelines for the diagnosis and treatment of postmenopausal osteoporosis - 2016.Endocr Pract. 2016 Sep 2; 22(Suppl 4): 1-42.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Kanis J., McCloskey E., Johansson H., Cooper C., Rizzoli R., Reginster J. European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Osteoporosis International. 2013; 24(1): 23-57. doi: 10.1007/s00198-012-2074-y.</mixed-citation><mixed-citation xml:lang="en">Kanis J., McCloskey E., Johansson H., Cooper C., Rizzoli R., Reginster J. European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Osteoporosis International. 2013; 24(1): 23-57. doi: 10.1007/s00198-012-2074-y.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Raman-Wilms L. Book Review: Guidelines for Preclinical Evaluation and Clinical Trials in Osteoporosis. Annals of Pharmacotherapy. 1999; 33(12): 1377-1378. doi: 10. 1177/106002809903301207.</mixed-citation><mixed-citation xml:lang="en">Raman-Wilms L. Book Review: Guidelines for Preclinical Evaluation and Clinical Trials in Osteoporosis. Annals of Pharmacotherapy. 1999; 33(12): 1377-1378. doi: 10. 1177/106002809903301207.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">American Association of Orthopedic Surgeon Position Statement, 1159, December 2009.</mixed-citation><mixed-citation xml:lang="en">American Association of Orthopedic Surgeon Position Statement, 1159, December 2009.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Лесняк О.М., Ершова О.Б. Аудит состояния проблемы остеопороза в странах Восточной Европы и Центральной Азии 2010. Naturaprint; 2011.</mixed-citation><mixed-citation xml:lang="en">Лесняк О.М., Ершова О.Б. Аудит состояния проблемы остеопороза в странах Восточной Европы и Центральной Азии 2010. Naturaprint; 2011.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Дедов И.И., Мельниченко Г.А., Белая Ж.Е., Рожинская Л.Я.: «Остеопороз - от редкого симптома эндокринных болезней до безмолвной эпидемии 20-21 века» // Проблемы Эндокринологии, 2011, том 57. Стр. 35-45.</mixed-citation><mixed-citation xml:lang="en">Дедов И.И., Мельниченко Г.А., Белая Ж.Е., Рожинская Л.Я.: «Остеопороз - от редкого симптома эндокринных болезней до безмолвной эпидемии 20-21 века» // Проблемы Эндокринологии, 2011, том 57. Стр. 35-45.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Ершова О.Б., Белова К.Ю., Белов М.В., Ганерт О.А., Гладкова Е.Н., Ходырев В.Н., Лесняк О.М., Давтян В.Г., Пилюкова Р.И., Романова М.А., Синицина О.С Эпидемиология переломов проксимального отдела бедренной кости у городского населения Российской Федерации: результаты многоцентрового исследования. Форум остеопороза, 23-25 сентября, 2012; Санкт-Петербург. Материалы научно-практической конференции «Остеопороз - важнейшая мультидисциплинарная проблема здравоохранения XXI века»; 23-27.</mixed-citation><mixed-citation xml:lang="en">Ершова О.Б., Белова К.Ю., Белов М.В., Ганерт О.А., Гладкова Е.Н., Ходырев В.Н., Лесняк О.М., Давтян В.Г., Пилюкова Р.И., Романова М.А., Синицина О.С Эпидемиология переломов проксимального отдела бедренной кости у городского населения Российской Федерации: результаты многоцентрового исследования. Форум остеопороза, 23-25 сентября, 2012; Санкт-Петербург. Материалы научно-практической конференции «Остеопороз - важнейшая мультидисциплинарная проблема здравоохранения XXI века»; 23-27.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Меньшикова Л.В., Храмцова Н.А., Ершова О.Б. Ближайшие и отдаленные исходы переломов проксимального отдела бедра у лиц пожилого возраста и их медикосоциальные последствия (по данным многоцентрового исследования) // Остеопороз и остеопатии. 2002; 1: 8-11.</mixed-citation><mixed-citation xml:lang="en">Меньшикова Л.В., Храмцова Н.А., Ершова О.Б. Ближайшие и отдаленные исходы переломов проксимального отдела бедра у лиц пожилого возраста и их медикосоциальные последствия (по данным многоцентрового исследования) // Остеопороз и остеопатии. 2002; 1: 8-11.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Добровольская О.В. Осложненный остеопороз: минеральная плотность костной ткани различных отделов скелета, качество жизни, приверженность терапии и затраты на лечение: автореферат дис.. кандидата медицинских наук: 14.01.22. - Москва, 2016. - 22 с. Ревматология 9 16-14/862.</mixed-citation><mixed-citation xml:lang="en">Добровольская О.В. Осложненный остеопороз: минеральная плотность костной ткани различных отделов скелета, качество жизни, приверженность терапии и затраты на лечение: автореферат дис.. кандидата медицинских наук: 14.01.22. - Москва, 2016. - 22 с. Ревматология 9 16-14/862.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Kanis J., Johnell O., Oden A., Johansson H., McCloskey E. FRAX™ and the assessment of fracture probability in men and women from the UK. Osteoporosis International. 2008; 19(4): 385-397. doi: 10.1007/s00198-007-0543-5.</mixed-citation><mixed-citation xml:lang="en">Kanis J., Johnell O., Oden A., Johansson H., McCloskey E. FRAX™ and the assessment of fracture probability in men and women from the UK. Osteoporosis International. 2008; 19(4): 385-397. doi: 10.1007/s00198-007-0543-5.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Burch J., Rice S., Yang H. et al. Systematic review of the use of bone turnover markers for monitoring the response to osteoporosis treatment: the secondary prevention of fractures, and primary prevention of fractures in high-risk groups. Health Technology Assessment. 2014; 18(11). doi: 10.3310/hta18110.</mixed-citation><mixed-citation xml:lang="en">Burch J., Rice S., Yang H. et al. Systematic review of the use of bone turnover markers for monitoring the response to osteoporosis treatment: the secondary prevention of fractures, and primary prevention of fractures in high-risk groups. Health Technology Assessment. 2014; 18(11). doi: 10.3310/hta18110.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Bergmann P., Body J., Boonen S. et al. Evidence-based guidelines for the use of biochemical markers of bone turnover in the selection and monitoring of bisphosphonate treatment in osteoporosis: a consensus document of the Belgian Bone Club. International Journal of Clinical Practice. 2009; 63(1): 19-26. doi: 10.1111/j.1742-1241.2008.01911.x.</mixed-citation><mixed-citation xml:lang="en">Bergmann P., Body J., Boonen S. et al. Evidence-based guidelines for the use of biochemical markers of bone turnover in the selection and monitoring of bisphosphonate treatment in osteoporosis: a consensus document of the Belgian Bone Club. International Journal of Clinical Practice. 2009; 63(1): 19-26. doi: 10.1111/j.1742-1241.2008.01911.x.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Ravn P., Hosking D., Thompson D. et al. Monitoring of Alendronate Treatment and Prediction of Effect on Bone Mass by Biochemical Markers in the Early Postmenopausal Intervention Cohort Study1. The Journal of Clinical Endocrinology &amp; Metabolism. 1999; 84(7): 2363-2368. doi: 10.1210/jcem.84.7.5847.</mixed-citation><mixed-citation xml:lang="en">Ravn P., Hosking D., Thompson D. et al. Monitoring of Alendronate Treatment and Prediction of Effect on Bone Mass by Biochemical Markers in the Early Postmenopausal Intervention Cohort Study1. The Journal of Clinical Endocrinology &amp; Metabolism. 1999; 84(7): 2363-2368. doi: 10.1210/jcem.84.7.5847.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Fink E., Cormier C., Steinmetz P., Kindermans C., Le Bouc Y., Souberbielle J. Differences in the Capacity of Several Biochemical Bone Markers to Assess High Bone Turnover in Early Menopause and Response to Alendronate Therapy. Osteoporosis International. 2000; 11(4): 295-303. doi: 10.1007/ pl00004183.</mixed-citation><mixed-citation xml:lang="en">Fink E., Cormier C., Steinmetz P., Kindermans C., Le Bouc Y., Souberbielle J. Differences in the Capacity of Several Biochemical Bone Markers to Assess High Bone Turnover in Early Menopause and Response to Alendronate Therapy. Osteoporosis International. 2000; 11(4): 295-303. doi: 10.1007/ pl00004183.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Bauer D., Black D., Garnero P. et al. Change in Bone Turnover and Hip, Non-Spine, and Vertebral Fracture in Alendronate-Treated Women: The Fracture Intervention Trial. J Bone Miner Res. 2004; 19(8): 1250-1258. doi: 10.1359/jbmr.040512.</mixed-citation><mixed-citation xml:lang="en">Bauer D., Black D., Garnero P. et al. Change in Bone Turnover and Hip, Non-Spine, and Vertebral Fracture in Alendronate-Treated Women: The Fracture Intervention Trial. J Bone Miner Res. 2004; 19(8): 1250-1258. doi: 10.1359/jbmr.040512.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Eastell R., Barton I., Hannon R., Chines A., Garnero P., Delmas P. Relationship of Early Changes in Bone Resorption to the Reduction in Fracture Risk With Risedronate. J Bone Miner Res. 2003; 18(6): 1051-1056. doi: 10.1359/jbmr.2003.18.6.1051.</mixed-citation><mixed-citation xml:lang="en">Eastell R., Barton I., Hannon R., Chines A., Garnero P., Delmas P. Relationship of Early Changes in Bone Resorption to the Reduction in Fracture Risk With Risedronate. J Bone Miner Res. 2003; 18(6): 1051-1056. doi: 10.1359/jbmr.2003.18.6.1051.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Delmas P., Recker R., Chesnut C. et al. Daily and intermittent oral ibandronate normalize bone turnover and provide significant reduction in vertebral fracture risk: results from the BONE study. Osteoporosis International. 2004; 15(10). doi: 10.1007/s00198-004-1602-9.</mixed-citation><mixed-citation xml:lang="en">Delmas P., Recker R., Chesnut C. et al. Daily and intermittent oral ibandronate normalize bone turnover and provide significant reduction in vertebral fracture risk: results from the BONE study. Osteoporosis International. 2004; 15(10). doi: 10.1007/s00198-004-1602-9.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Reginster JGieschke R. Clinical Utility of a Pharmacostatistical Model for Ibandronate in Postmenopausal Osteoporosis. CDM. 2006; 7(7): 827-836. doi: 10.2174/138920006778520624.</mixed-citation><mixed-citation xml:lang="en">Reginster JGieschke R. Clinical Utility of a Pharmacostatistical Model for Ibandronate in Postmenopausal Osteoporosis. CDM. 2006; 7(7): 827-836. doi: 10.2174/138920006778520624.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Krege J., Lane N., Harris J., Miller P. PINP as a biological response marker during teriparatide treatment for osteoporosis. Osteoporosis International. 2014; 25(9): 2159-2171. doi: 10.1007/s00198-014-2646-0.</mixed-citation><mixed-citation xml:lang="en">Krege J., Lane N., Harris J., Miller P. PINP as a biological response marker during teriparatide treatment for osteoporosis. Osteoporosis International. 2014; 25(9): 2159-2171. doi: 10.1007/s00198-014-2646-0.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Imaz I., Zegarra P., Gonzalez-Enriquez J., Rubio B., Alcazar R., Amate J. Poor bisphosphonate adherence for treatment of osteoporosis increases fracture risk: systematic review and meta-analysis. Osteoporosis International. 2009; 21(11): 1943-1951. doi: 10.1007/s00198-009-1134-4.</mixed-citation><mixed-citation xml:lang="en">Imaz I., Zegarra P., Gonzalez-Enriquez J., Rubio B., Alcazar R., Amate J. Poor bisphosphonate adherence for treatment of osteoporosis increases fracture risk: systematic review and meta-analysis. Osteoporosis International. 2009; 21(11): 1943-1951. doi: 10.1007/s00198-009-1134-4.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Dresner-Pollak R., Parker R., Poku M., Thompson J., Seibel M., Greenspan S. Biochemical Markers of Bone Turnover Reflect Femoral Bone Loss in Elderly Women. Calcified Tissue International. 1996; 59(5): 328-333. doi: 10.1007/s002239900135.</mixed-citation><mixed-citation xml:lang="en">Dresner-Pollak R., Parker R., Poku M., Thompson J., Seibel M., Greenspan S. Biochemical Markers of Bone Turnover Reflect Femoral Bone Loss in Elderly Women. Calcified Tissue International. 1996; 59(5): 328-333. doi: 10.1007/s002239900135.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Ross PKnowlton W. Rapid Bone Loss Is Associated with Increased Levels of Biochemical Markers. J Bone Miner Res. 1998; 13(2): 297-302. doi: 10.1359/jbmr.1998.13.2.297.</mixed-citation><mixed-citation xml:lang="en">Ross PKnowlton W. Rapid Bone Loss Is Associated with Increased Levels of Biochemical Markers. J Bone Miner Res. 1998; 13(2): 297-302. doi: 10.1359/jbmr.1998.13.2.297.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">Hansen M.A., Overgaard K., Riis B.J. et al. Role of peak bone mass and bone loss in postmenopausal osteoporosis: 12 year study. BMJ 1991; 303: 961-4.</mixed-citation><mixed-citation xml:lang="en">Hansen M.A., Overgaard K., Riis B.J. et al. Role of peak bone mass and bone loss in postmenopausal osteoporosis: 12 year study. BMJ 1991; 303: 961-4.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Garnero P., Sornay-Rendu E., Duboeuf F., Delmas P. Markers of Bone Turnover Predict Postmenopausal Forearm Bone Loss Over 4 Years: The OFELY Study. J Bone Miner Res. 1999; 14(9): 1614-1621. doi: 10.1359/jbmr.1999.14.9.1614.</mixed-citation><mixed-citation xml:lang="en">Garnero P., Sornay-Rendu E., Duboeuf F., Delmas P. Markers of Bone Turnover Predict Postmenopausal Forearm Bone Loss Over 4 Years: The OFELY Study. J Bone Miner Res. 1999; 14(9): 1614-1621. doi: 10.1359/jbmr.1999.14.9.1614.</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Boonen S., Body J., Boutsen Y. et al. Evidence-based guidelines for the treatment of postmenopausal osteoporosis: a consensus document of the Belgian Bone Club. Osteoporosis International. 2005; 16(3): 239-254. doi: 10.1007/s00198-004-1812-1.</mixed-citation><mixed-citation xml:lang="en">Boonen S., Body J., Boutsen Y. et al. Evidence-based guidelines for the treatment of postmenopausal osteoporosis: a consensus document of the Belgian Bone Club. Osteoporosis International. 2005; 16(3): 239-254. doi: 10.1007/s00198-004-1812-1.</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Schousboe J., Bauer D., Nyman J., Kane R., Melton L., Ensrud K. Potential for bone turnover markers to cost-effectively identify and select post-menopausal osteopenic women at high risk of fracture for bisphosphonate therapy. Osteoporosis International. 2006; 18(2): 201-210. doi: 10.1007/s00198-006-0218-7.</mixed-citation><mixed-citation xml:lang="en">Schousboe J., Bauer D., Nyman J., Kane R., Melton L., Ensrud K. Potential for bone turnover markers to cost-effectively identify and select post-menopausal osteopenic women at high risk of fracture for bisphosphonate therapy. Osteoporosis International. 2006; 18(2): 201-210. doi: 10.1007/s00198-006-0218-7.</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">McNabb B., Vittinghoff E., Schwartz A. et al. BMD changes and predictors of increased bone loss in postmenopausal women after a 5-year course of alendronate. J Bone Miner Res. 2013; 28(6): 1319-1327. doi: 10.1002/jbmr.1864.</mixed-citation><mixed-citation xml:lang="en">McNabb B., Vittinghoff E., Schwartz A. et al. BMD changes and predictors of increased bone loss in postmenopausal women after a 5-year course of alendronate. J Bone Miner Res. 2013; 28(6): 1319-1327. doi: 10.1002/jbmr.1864.</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Bauer D., Schwartz A., Palermo L. et al. Fracture Prediction After Discontinuation of 4 to 5 Years of Alendronate Therapy. JAMA Internal Medicine. 2014; 174(7): 1126.</mixed-citation><mixed-citation xml:lang="en">Bauer D., Schwartz A., Palermo L. et al. Fracture Prediction After Discontinuation of 4 to 5 Years of Alendronate Therapy. JAMA Internal Medicine. 2014; 174(7): 1126.</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Cosman F., Cauley J., Eastell R. et al. Reassessment of Fracture Risk in Women After 3 Years of Treatment With Zoledronic Acid: When is it Reasonable to Discontinue Treatment?. The Journal of Clinical Endocrinology &amp; Metabolism. 2014; 99(12): 4546-4554. doi: 10.1210/jc.2014-1971.</mixed-citation><mixed-citation xml:lang="en">Cosman F., Cauley J., Eastell R. et al. Reassessment of Fracture Risk in Women After 3 Years of Treatment With Zoledronic Acid: When is it Reasonable to Discontinue Treatment?. The Journal of Clinical Endocrinology &amp; Metabolism. 2014; 99(12): 4546-4554. doi: 10.1210/jc.2014-1971.</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">Bauer D., Garnero P., Hochberg M. et al. Pretreatment Levels of Bone Turnover and the Antifracture Efficacy of Alendronate: The Fracture Intervention Trial. J Bone Miner Res. 2005; 21(2): 292-299. doi: 10.1359/jbmr.051018.</mixed-citation><mixed-citation xml:lang="en">Bauer D., Garnero P., Hochberg M. et al. Pretreatment Levels of Bone Turnover and the Antifracture Efficacy of Alendronate: The Fracture Intervention Trial. J Bone Miner Res. 2005; 21(2): 292-299. doi: 10.1359/jbmr.051018.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Seibel M., Naganathan V., Barton I., Grauer A. Relationship Between Pretreatment Bone Resorption and Vertebral Fracture Incidence in Postmenopausal Osteoporotic Women Treated With Risedronate. J Bone Miner Res. 2003; 19(2): 323-329. doi: 10.1359/jbmr.0301231.</mixed-citation><mixed-citation xml:lang="en">Seibel M., Naganathan V., Barton I., Grauer A. Relationship Between Pretreatment Bone Resorption and Vertebral Fracture Incidence in Postmenopausal Osteoporotic Women Treated With Risedronate. J Bone Miner Res. 2003; 19(2): 323-329. doi: 10.1359/jbmr.0301231.</mixed-citation></citation-alternatives></ref><ref id="cit34"><label>34</label><citation-alternatives><mixed-citation xml:lang="ru">Cosman F., de Beur S., LeBoff M., de Beur S.J., Tanner B. Clinician’s Guide to Prevention and Treatment of Osteoporosis. National Osteoporosis Foundation 1150 17th St., NW, Suite 850, Washington, DC 20036, Release Date: April 1, 2014.</mixed-citation><mixed-citation xml:lang="en">Cosman F., de Beur S., LeBoff M., de Beur S.J., Tanner B. Clinician’s Guide to Prevention and Treatment of Osteoporosis. National Osteoporosis Foundation 1150 17th St., NW, Suite 850, Washington, DC 20036, Release Date: April 1, 2014.</mixed-citation></citation-alternatives></ref><ref id="cit35"><label>35</label><citation-alternatives><mixed-citation xml:lang="ru">Ross P. Pre-Existing Fractures and Bone Mass Predict Vertebral Fracture Incidence in Women. Annals of Internal Medicine. 1991; 114(11): 919. doi: 10.7326/0003-4819-114-11-919.</mixed-citation><mixed-citation xml:lang="en">Ross P. Pre-Existing Fractures and Bone Mass Predict Vertebral Fracture Incidence in Women. Annals of Internal Medicine. 1991; 114(11): 919. doi: 10.7326/0003-4819-114-11-919.</mixed-citation></citation-alternatives></ref><ref id="cit36"><label>36</label><citation-alternatives><mixed-citation xml:lang="ru">Kanis J., Melton L., Christiansen C., Johnston C., Khaltaev N. The diagnosis of osteoporosis. J Bone Miner Res. 2009; 9(8): 1137-1141. doi: 10.1002/jbmr.5650090802.</mixed-citation><mixed-citation xml:lang="en">Kanis J., Melton L., Christiansen C., Johnston C., Khaltaev N. The diagnosis of osteoporosis. J Bone Miner Res. 2009; 9(8): 1137-1141. doi: 10.1002/jbmr.5650090802.</mixed-citation></citation-alternatives></ref><ref id="cit37"><label>37</label><citation-alternatives><mixed-citation xml:lang="ru">Genant H.K., Jergas M. Assessment of prevalent and incident vertebral fractures in osteoporosis research. Osteoporosis Int. 2003; 14(3): 43-55.</mixed-citation><mixed-citation xml:lang="en">Genant H.K., Jergas M. Assessment of prevalent and incident vertebral fractures in osteoporosis research. Osteoporosis Int. 2003; 14(3): 43-55.</mixed-citation></citation-alternatives></ref><ref id="cit38"><label>38</label><citation-alternatives><mixed-citation xml:lang="ru">Yamamoto M., Yamaguchi T., Yamauchi M., Kaji H., Sugimoto T. Diabetic patients have an increased risk of vertebral fractures independent of BMD or diabetic complications.J Bone Miner Res. 2009 Apr; 24(4): 702-9. doi: 10.1359/jbmr.081207.</mixed-citation><mixed-citation xml:lang="en">Yamamoto M., Yamaguchi T., Yamauchi M., Kaji H., Sugimoto T. Diabetic patients have an increased risk of vertebral fractures independent of BMD or diabetic complications.J Bone Miner Res. 2009 Apr; 24(4): 702-9. doi: 10.1359/jbmr.081207.</mixed-citation></citation-alternatives></ref><ref id="cit39"><label>39</label><citation-alternatives><mixed-citation xml:lang="ru">Dede A.D., Tournis S., Dontas I., Trovas G. Type 2 diabetes mellitus and fracture risk. Metabolism. 2014 Dec; 63(12): 1480-90. doi: 10.1016/j.metabol.2014.09.002.</mixed-citation><mixed-citation xml:lang="en">Dede A.D., Tournis S., Dontas I., Trovas G. Type 2 diabetes mellitus and fracture risk. Metabolism. 2014 Dec; 63(12): 1480-90. doi: 10.1016/j.metabol.2014.09.002.</mixed-citation></citation-alternatives></ref><ref id="cit40"><label>40</label><citation-alternatives><mixed-citation xml:lang="ru">Schousboe J., Ensrud K., Nyman J., Kane R., Melton L. Potential cost-effective use of spine radiographs to detect vertebral deformity and select osteopenic post-menopausal women for amino-bisphosphonate therapy. Osteoporosis International. 2005; 16(12): 1883-1893. doi: 10.1007/s00198-005-1956-7.</mixed-citation><mixed-citation xml:lang="en">Schousboe J., Ensrud K., Nyman J., Kane R., Melton L. Potential cost-effective use of spine radiographs to detect vertebral deformity and select osteopenic post-menopausal women for amino-bisphosphonate therapy. Osteoporosis International. 2005; 16(12): 1883-1893. doi: 10.1007/s00198-005-1956-7.</mixed-citation></citation-alternatives></ref><ref id="cit41"><label>41</label><citation-alternatives><mixed-citation xml:lang="ru">Genant H., Wu C., van Kuijk C., Nevitt M. Vertebral fracture assessment using a semiquantitative technique. J Bone Miner Res. 2009; 8(9): 1137-1148. doi: 10.1002/jbmr.5650080915.</mixed-citation><mixed-citation xml:lang="en">Genant H., Wu C., van Kuijk C., Nevitt M. Vertebral fracture assessment using a semiquantitative technique. J Bone Miner Res. 2009; 8(9): 1137-1148. doi: 10.1002/jbmr.5650080915.</mixed-citation></citation-alternatives></ref><ref id="cit42"><label>42</label><citation-alternatives><mixed-citation xml:lang="ru">Kazawa N. T2WI MRI and MRI-MDCT correlations of the osteoporotic vertebral compressive fractures. European Journal of Radiology. 2012; 81(7): 1630-1636. doi: 10.1016/j.ejrad.2011.04.052.</mixed-citation><mixed-citation xml:lang="en">Kazawa N. T2WI MRI and MRI-MDCT correlations of the osteoporotic vertebral compressive fractures. European Journal of Radiology. 2012; 81(7): 1630-1636. doi: 10.1016/j.ejrad.2011.04.052.</mixed-citation></citation-alternatives></ref><ref id="cit43"><label>43</label><citation-alternatives><mixed-citation xml:lang="ru">Baum T., Karampinos D., Liebl H., Rummeny E., Waldt S., Bauer J. High-Resolution Bone Imaging for Osteoporosis Diagnostics and Therapy Monitoring Using Clinical MDCT and MRI. CMC. 2013; 20(38): 4844-4852. doi: 10.2174/09298 673113206660279.</mixed-citation><mixed-citation xml:lang="en">Baum T., Karampinos D., Liebl H., Rummeny E., Waldt S., Bauer J. High-Resolution Bone Imaging for Osteoporosis Diagnostics and Therapy Monitoring Using Clinical MDCT and MRI. CMC. 2013; 20(38): 4844-4852. doi: 10.2174/09298 673113206660279.</mixed-citation></citation-alternatives></ref><ref id="cit44"><label>44</label><citation-alternatives><mixed-citation xml:lang="ru">Kanis J., Johnell O., De Laet C., Jonsson B., Oden A., Ogelsby A. International Variations in Hip Fracture Probabilities: Implications for Risk Assessment. J Bone Miner Res. 2002; 17(7): 1237-1244. doi: 10.1359/jbmr.2002.17.7.1237.</mixed-citation><mixed-citation xml:lang="en">Kanis J., Johnell O., De Laet C., Jonsson B., Oden A., Ogelsby A. International Variations in Hip Fracture Probabilities: Implications for Risk Assessment. J Bone Miner Res. 2002; 17(7): 1237-1244. doi: 10.1359/jbmr.2002.17.7.1237.</mixed-citation></citation-alternatives></ref><ref id="cit45"><label>45</label><citation-alternatives><mixed-citation xml:lang="ru">De Laet C., Van Hout B., Burger H., Weel A., Hofman A., Pols H. Hip Fracture Prediction in Elderly Men and Women: Validation in the Rotterdam Study. J Bone Miner Res. 2009; 13(10): 1587-1593. doi: 10.1359/jbmr.1998.13.10.1587.</mixed-citation><mixed-citation xml:lang="en">De Laet C., Van Hout B., Burger H., Weel A., Hofman A., Pols H. Hip Fracture Prediction in Elderly Men and Women: Validation in the Rotterdam Study. J Bone Miner Res. 2009; 13(10): 1587-1593. doi: 10.1359/jbmr.1998.13.10.1587.</mixed-citation></citation-alternatives></ref><ref id="cit46"><label>46</label><citation-alternatives><mixed-citation xml:lang="ru">Kanis J., Bianchi G., Bilezikian J. et al. Towards a diagnostic and therapeutic consensus in male osteoporosis. Osteoporosis International. 2011; 22(11): 2789-2798. doi: 10.1007/s00198-011-1632-z.</mixed-citation><mixed-citation xml:lang="en">Kanis J., Bianchi G., Bilezikian J. et al. Towards a diagnostic and therapeutic consensus in male osteoporosis. Osteoporosis International. 2011; 22(11): 2789-2798. doi: 10.1007/s00198-011-1632-z.</mixed-citation></citation-alternatives></ref><ref id="cit47"><label>47</label><citation-alternatives><mixed-citation xml:lang="ru">Kanis J.A., Harvey N.C., Cooper C. et al. A systematic review of intervention thresholds based on FRAX: A report prepared for the National Osteoporosis Guideline Group and the International Osteoporosis Foundation. Arch Osteoporos. 2016 Dec; 11(1): 25. doi: 10.1007/s11657-016-0278-z.</mixed-citation><mixed-citation xml:lang="en">Kanis J.A., Harvey N.C., Cooper C. et al. A systematic review of intervention thresholds based on FRAX: A report prepared for the National Osteoporosis Guideline Group and the International Osteoporosis Foundation. Arch Osteoporos. 2016 Dec; 11(1): 25. doi: 10.1007/s11657-016-0278-z.</mixed-citation></citation-alternatives></ref><ref id="cit48"><label>48</label><citation-alternatives><mixed-citation xml:lang="ru">Lewiecki E., Watts N., McClung M. et al. Official Positions of the International Society for Clinical Densitometry. The Journal of Clinical Endocrinology &amp; Metabolism. 2004; 89(8): 3651-3655. doi: 10.1210/jc.2004-0124.</mixed-citation><mixed-citation xml:lang="en">Lewiecki E., Watts N., McClung M. et al. Official Positions of the International Society for Clinical Densitometry. The Journal of Clinical Endocrinology &amp; Metabolism. 2004; 89(8): 3651-3655. doi: 10.1210/jc.2004-0124.</mixed-citation></citation-alternatives></ref><ref id="cit49"><label>49</label><citation-alternatives><mixed-citation xml:lang="ru">Lesnyak O., Ershova O., Belova K. et al. Epidemiology of fracture in the Russian Federation and the development of a FRAX model. Arch Osteoporos. 2012; 7(1-2): 67-73. doi: 10.1007/s11657-012-0082-3.</mixed-citation><mixed-citation xml:lang="en">Lesnyak O., Ershova O., Belova K. et al. Epidemiology of fracture in the Russian Federation and the development of a FRAX model. Arch Osteoporos. 2012; 7(1-2): 67-73. doi: 10.1007/s11657-012-0082-3.</mixed-citation></citation-alternatives></ref><ref id="cit50"><label>50</label><citation-alternatives><mixed-citation xml:lang="ru">Алексеева Л.И., Баранова И.А., Белова К.Ю., Ершова О.Б., Зазерская И.Е., Зоткин Е.Г, Лесняк О.М., Никитинская О.А., Рожинская Л.Я., Скрипникова И.А., Смирнов А.В., Щеплягина Л.А.: Клинические рекомендации по профилактике и ведению больных с остеопорозом под редакцией О.М. Лесняк. Литера;. Ярославль, 2012: 23.</mixed-citation><mixed-citation xml:lang="en">Алексеева Л.И., Баранова И.А., Белова К.Ю., Ершова О.Б., Зазерская И.Е., Зоткин Е.Г, Лесняк О.М., Никитинская О.А., Рожинская Л.Я., Скрипникова И.А., Смирнов А.В., Щеплягина Л.А.: Клинические рекомендации по профилактике и ведению больных с остеопорозом под редакцией О.М. Лесняк. Литера;. Ярославль, 2012: 23.</mixed-citation></citation-alternatives></ref><ref id="cit51"><label>51</label><citation-alternatives><mixed-citation xml:lang="ru">Никитинская О.А., Торопцова Н.В. Оценка риска переломов с использованием модели FRAX® (ретроспективное десятилетнее исследование) Альманах клинической медицины. 2014; 43: 50-55.</mixed-citation><mixed-citation xml:lang="en">Никитинская О.А., Торопцова Н.В. Оценка риска переломов с использованием модели FRAX® (ретроспективное десятилетнее исследование) Альманах клинической медицины. 2014; 43: 50-55.</mixed-citation></citation-alternatives></ref><ref id="cit52"><label>52</label><citation-alternatives><mixed-citation xml:lang="ru">National Osteoporosis Foundation (NOF) and International Society for Clinical Densitometry (ISCD). Recommendations to DXA Manufacturers for FRAX® Implementation. Available http://www.nof.org/files/nof/public/content/resource/862/files/392.pdf. Accessed January 28, 2013</mixed-citation><mixed-citation xml:lang="en">National Osteoporosis Foundation (NOF) and International Society for Clinical Densitometry (ISCD). Recommendations to DXA Manufacturers for FRAX® Implementation. Available http://www.nof.org/files/nof/public/content/resource/862/files/392.pdf. Accessed January 28, 2013</mixed-citation></citation-alternatives></ref><ref id="cit53"><label>53</label><citation-alternatives><mixed-citation xml:lang="ru">Management of postmenopausal osteoporosis: position statement of The North American Menopause Society. Menopause. 2002: 84-101. doi: 10.1097/00042192-200203000-00003.</mixed-citation><mixed-citation xml:lang="en">Management of postmenopausal osteoporosis: position statement of The North American Menopause Society. Menopause. 2002: 84-101. doi: 10.1097/00042192-200203000-00003.</mixed-citation></citation-alternatives></ref><ref id="cit54"><label>54</label><citation-alternatives><mixed-citation xml:lang="ru">ISCD positions. Journal of Clinical Densitometry. 2004; 7(1).</mixed-citation><mixed-citation xml:lang="en">ISCD positions. Journal of Clinical Densitometry. 2004; 7(1).</mixed-citation></citation-alternatives></ref><ref id="cit55"><label>55</label><citation-alternatives><mixed-citation xml:lang="ru">Official Positions of the International Society for Clinical Densitometry. Copyright ISCD, October 2007.</mixed-citation><mixed-citation xml:lang="en">Official Positions of the International Society for Clinical Densitometry. Copyright ISCD, October 2007.</mixed-citation></citation-alternatives></ref><ref id="cit56"><label>56</label><citation-alternatives><mixed-citation xml:lang="ru">Nelson H.D., Haney E.M., Chou R., Dana T., Fu R., Bougatsos C. Screening for Osteoporosis: Systematic Review to Update the 2002 US Preventive Services Task Force Recommendation. Rockville (MD): Agency for Healthcare Research and Quality (US); 2010 Jul. Report No.: 10-05145-EF-1.</mixed-citation><mixed-citation xml:lang="en">Nelson H.D., Haney E.M., Chou R., Dana T., Fu R., Bougatsos C. Screening for Osteoporosis: Systematic Review to Update the 2002 US Preventive Services Task Force Recommendation. Rockville (MD): Agency for Healthcare Research and Quality (US); 2010 Jul. Report No.: 10-05145-EF-1.</mixed-citation></citation-alternatives></ref><ref id="cit57"><label>57</label><citation-alternatives><mixed-citation xml:lang="ru">Bonnick S. Bone Densitometry in Clinical Practice. Humana Press Inc. 2004: 411.</mixed-citation><mixed-citation xml:lang="en">Bonnick S. Bone Densitometry in Clinical Practice. Humana Press Inc. 2004: 411.</mixed-citation></citation-alternatives></ref><ref id="cit58"><label>58</label><citation-alternatives><mixed-citation xml:lang="ru">McCloskey E., Odén A., Harvey N. et al. A meta-analysis of trabecular bone score in fracture risk prediction and its relationship to FRAX. J Bone Miner Res. 2015: n/a-n/a. doi: 10.1002/jbmr.2734.</mixed-citation><mixed-citation xml:lang="en">McCloskey E., Odén A., Harvey N. et al. A meta-analysis of trabecular bone score in fracture risk prediction and its relationship to FRAX. J Bone Miner Res. 2015: n/a-n/a. doi: 10.1002/jbmr.2734.</mixed-citation></citation-alternatives></ref><ref id="cit59"><label>59</label><citation-alternatives><mixed-citation xml:lang="ru">Bousson V., Bergot C., Sutter B., Levitz P., Cortet B. Trabecular bone score (TBS): available knowledge, clinical relevance, and future prospects. Osteoporosis International. 2011; 23(5): 1489-1501. doi: 10.1007/s00198-011-1824-6.</mixed-citation><mixed-citation xml:lang="en">Bousson V., Bergot C., Sutter B., Levitz P., Cortet B. Trabecular bone score (TBS): available knowledge, clinical relevance, and future prospects. Osteoporosis International. 2011; 23(5): 1489-1501. doi: 10.1007/s00198-011-1824-6.</mixed-citation></citation-alternatives></ref><ref id="cit60"><label>60</label><citation-alternatives><mixed-citation xml:lang="ru">International Society for Clinical Densitometry. 2013 Official Positions - Adult. http://www.iscd.org/official-positions/2013-iscd-official-positions-adult. Ссылка активна на 05.05.2016.</mixed-citation><mixed-citation xml:lang="en">International Society for Clinical Densitometry. 2013 Official Positions - Adult. http://www.iscd.org/official-positions/2013-iscd-official-positions-adult. Ссылка активна на 05.05.2016.</mixed-citation></citation-alternatives></ref><ref id="cit61"><label>61</label><citation-alternatives><mixed-citation xml:lang="ru">Black D.M., Cummings S.R., Karpf D.B. et al. Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group. Lancet. 1996; 348: 1535-1541.</mixed-citation><mixed-citation xml:lang="en">Black D.M., Cummings S.R., Karpf D.B. et al. Randomised trial of effect of alendronate on risk of fracture in women with existing vertebral fractures. Fracture Intervention Trial Research Group. Lancet. 1996; 348: 1535-1541.</mixed-citation></citation-alternatives></ref><ref id="cit62"><label>62</label><citation-alternatives><mixed-citation xml:lang="ru">Black D., Delmas P., Eastell R. et al. Once-Yearly Zoledronic Acid for Treatment of Postmenopausal Osteoporosis. N Engl J Med. 2007 May 3; 356(18): 1809-22 DOI: 10.1056/NEJMoa067312.</mixed-citation><mixed-citation xml:lang="en">Black D., Delmas P., Eastell R. et al. Once-Yearly Zoledronic Acid for Treatment of Postmenopausal Osteoporosis. N Engl J Med. 2007 May 3; 356(18): 1809-22 DOI: 10.1056/NEJMoa067312.</mixed-citation></citation-alternatives></ref><ref id="cit63"><label>63</label><citation-alternatives><mixed-citation xml:lang="ru">Cummings S.R., Black D.M., Thompson D.E. et al. Effect of alendronate on risk of fracture in women with low bone density but without vertebral fractures: results from the Fracture Intervention Trial. JAMA. 1998; 280: 2077-2082. doi: 10.1001/jama.280.24.2077</mixed-citation><mixed-citation xml:lang="en">Cummings S.R., Black D.M., Thompson D.E. et al. Effect of alendronate on risk of fracture in women with low bone density but without vertebral fractures: results from the Fracture Intervention Trial. JAMA. 1998; 280: 2077-2082. doi: 10.1001/jama.280.24.2077</mixed-citation></citation-alternatives></ref><ref id="cit64"><label>64</label><citation-alternatives><mixed-citation xml:lang="ru">Cummings S., Martin J., McClung M. et al. Denosumab for Prevention of Fractures in Postmenopausal Women With Osteoporosis. N Engl J Med. 2009 Aug 20; 361(8): 756-65. doi: 10.1056/NEJMoa0809493. Epub 2009 Aug 11.</mixed-citation><mixed-citation xml:lang="en">Cummings S., Martin J., McClung M. et al. Denosumab for Prevention of Fractures in Postmenopausal Women With Osteoporosis. N Engl J Med. 2009 Aug 20; 361(8): 756-65. doi: 10.1056/NEJMoa0809493. Epub 2009 Aug 11.</mixed-citation></citation-alternatives></ref><ref id="cit65"><label>65</label><citation-alternatives><mixed-citation xml:lang="ru">Saag K., Emkey R., Schnitzer T. et al. Alendronate for the Prevention and Treatment of Glucocorticoid-Induced Osteoporosis. Obstetrical &amp; Gynecological Survey. 1999; 54(1): 39-40. doi: 10.1097/00006254-199901000-00021</mixed-citation><mixed-citation xml:lang="en">Saag K., Emkey R., Schnitzer T. et al. Alendronate for the Prevention and Treatment of Glucocorticoid-Induced Osteoporosis. Obstetrical &amp; Gynecological Survey. 1999; 54(1): 39-40. doi: 10.1097/00006254-199901000-00021</mixed-citation></citation-alternatives></ref><ref id="cit66"><label>66</label><citation-alternatives><mixed-citation xml:lang="ru">Boonen S., Orwoll E., Wenderoth D., Stoner K., Eusebio R., Delmas P. Once-Weekly Risedronate in Men With Osteoporosis: Results of a 2-Year, Placebo-Controlled, Double-Blind, Multicenter Study. Journal of Bone and Mineral Research. 2009; 24(4): 719-725. doi: 10.1359/jbmr.081214</mixed-citation><mixed-citation xml:lang="en">Boonen S., Orwoll E., Wenderoth D., Stoner K., Eusebio R., Delmas P. Once-Weekly Risedronate in Men With Osteoporosis: Results of a 2-Year, Placebo-Controlled, Double-Blind, Multicenter Study. Journal of Bone and Mineral Research. 2009; 24(4): 719-725. doi: 10.1359/jbmr.081214</mixed-citation></citation-alternatives></ref><ref id="cit67"><label>67</label><citation-alternatives><mixed-citation xml:lang="ru">Eastell R., Devogelaer J., Peel N. et al. Prevention of Bone Loss with Risedronate in Glucocorticoid-Treated Rheumatoid Arthritis Patients. Osteoporosis International. 2000; 11(4): 331-337. doi: 10.1007/s001980070122</mixed-citation><mixed-citation xml:lang="en">Eastell R., Devogelaer J., Peel N. et al. Prevention of Bone Loss with Risedronate in Glucocorticoid-Treated Rheumatoid Arthritis Patients. Osteoporosis International. 2000; 11(4): 331-337. doi: 10.1007/s001980070122</mixed-citation></citation-alternatives></ref><ref id="cit68"><label>68</label><citation-alternatives><mixed-citation xml:lang="ru">Hakala M., Kröger H., Valleala H. et al. Once-monthly oral ibandronate provides significant improvement in bone mineral density in postmenopausal women treated with glucocorticoids for inflammatory rheumatic diseases: a 12-month, randomized, double-blind, placebo-controlled trial. Scandinavian Journal of Rheumatology. 2012; 41(4): 260-266. doi: 10.3109/03009742.2 012.664647</mixed-citation><mixed-citation xml:lang="en">Hakala M., Kröger H., Valleala H. et al. Once-monthly oral ibandronate provides significant improvement in bone mineral density in postmenopausal women treated with glucocorticoids for inflammatory rheumatic diseases: a 12-month, randomized, double-blind, placebo-controlled trial. Scandinavian Journal of Rheumatology. 2012; 41(4): 260-266. doi: 10.3109/03009742.2 012.664647</mixed-citation></citation-alternatives></ref><ref id="cit69"><label>69</label><citation-alternatives><mixed-citation xml:lang="ru">Cranney A., Wells G., Yetisir E. et al. Ibandronate for the prevention of nonvertebral fractures: a pooled analysis of individual patient data. Osteoporosis International. 2008; 20(2): 291-297. doi: 10.1007/s00198-008-0653-8</mixed-citation><mixed-citation xml:lang="en">Cranney A., Wells G., Yetisir E. et al. Ibandronate for the prevention of nonvertebral fractures: a pooled analysis of individual patient data. Osteoporosis International. 2008; 20(2): 291-297. doi: 10.1007/s00198-008-0653-8</mixed-citation></citation-alternatives></ref><ref id="cit70"><label>70</label><citation-alternatives><mixed-citation xml:lang="ru">Harris S., Blumentals W., Miller P. Ibandronate and the risk of non-vertebral and clinical fractures in women with postmenopausal osteoporosis: results of a meta-analysis of phase III studies. Current Medical Research and Opinion. 2007; 24(1): 237-245. doi: 10.1185/030079908x253717</mixed-citation><mixed-citation xml:lang="en">Harris S., Blumentals W., Miller P. Ibandronate and the risk of non-vertebral and clinical fractures in women with postmenopausal osteoporosis: results of a meta-analysis of phase III studies. Current Medical Research and Opinion. 2007; 24(1): 237-245. doi: 10.1185/030079908x253717</mixed-citation></citation-alternatives></ref><ref id="cit71"><label>71</label><citation-alternatives><mixed-citation xml:lang="ru">Boonen S., Reginster J., Kaufman J. et al. Fracture Risk and Zoledronic Acid Therapy in Men with Osteoporosis. New England Journal of Medicine. 2012; 367(18): 1714-1723</mixed-citation><mixed-citation xml:lang="en">Boonen S., Reginster J., Kaufman J. et al. Fracture Risk and Zoledronic Acid Therapy in Men with Osteoporosis. New England Journal of Medicine. 2012; 367(18): 1714-1723</mixed-citation></citation-alternatives></ref><ref id="cit72"><label>72</label><citation-alternatives><mixed-citation xml:lang="ru">Shane E., Burr D., Abrahamsen B. et al. Atypical Subtrochanteric and Diaphyseal Femoral Fractures: Second Report of a Task Force of the American Society for Bone and Mineral Research. J Bone Miner Res. 2013; 29(1): 1-23. doi: 10.1002/jbmr.1998</mixed-citation><mixed-citation xml:lang="en">Shane E., Burr D., Abrahamsen B. et al. Atypical Subtrochanteric and Diaphyseal Femoral Fractures: Second Report of a Task Force of the American Society for Bone and Mineral Research. J Bone Miner Res. 2013; 29(1): 1-23. doi: 10.1002/jbmr.1998</mixed-citation></citation-alternatives></ref><ref id="cit73"><label>73</label><citation-alternatives><mixed-citation xml:lang="ru">Kenneth W. Lyles, M.D., Cathleen S. Colôn-Emeric, M.D., M.H.Sc., Jay S. Magaziner, Ph.D., Jonathan D. Adachi, M.D., Carl F. Pieper, D.P.H., Carlos Mautalen, M.D., Lars Hyldstrup, M.D., D.M.Sc., Chris Recknor, M.D., Lars Nordsletten, M.D., Ph.D., Kathy A. Moore, R.N., Catherine Lavecchia, M.S., Jie Zhang, Ph.D., Peter Mesenbrink, Ph.D., Patricia K. Hodgson, B.A., Ken Abrams, M.D., John J. Orloff, M.D., Zebulun Horowitz, M.D., Erik Fink Eriksen, M.D., D.M.Sc., and Steven Boonen, M.D., Ph.D., for the HORIZON Recurrent Fracture Trial*Zoledronic Acid and Clinical Fractures and Mortality after Hip Fracture. N Engl J Med. 2007; 357: 1799-1809</mixed-citation><mixed-citation xml:lang="en">Kenneth W. Lyles, M.D., Cathleen S. Colôn-Emeric, M.D., M.H.Sc., Jay S. Magaziner, Ph.D., Jonathan D. Adachi, M.D., Carl F. Pieper, D.P.H., Carlos Mautalen, M.D., Lars Hyldstrup, M.D., D.M.Sc., Chris Recknor, M.D., Lars Nordsletten, M.D., Ph.D., Kathy A. Moore, R.N., Catherine Lavecchia, M.S., Jie Zhang, Ph.D., Peter Mesenbrink, Ph.D., Patricia K. Hodgson, B.A., Ken Abrams, M.D., John J. Orloff, M.D., Zebulun Horowitz, M.D., Erik Fink Eriksen, M.D., D.M.Sc., and Steven Boonen, M.D., Ph.D., for the HORIZON Recurrent Fracture Trial*Zoledronic Acid and Clinical Fractures and Mortality after Hip Fracture. N Engl J Med. 2007; 357: 1799-1809</mixed-citation></citation-alternatives></ref><ref id="cit74"><label>74</label><citation-alternatives><mixed-citation xml:lang="ru">McClung M, Miller P, Recknor C, Mesenbrink P, Bucci-Rechtweg C, Benhamou C. Zoledronic Acid for the Prevention of Bone Loss in Postmenopausal Women With Low Bone Mass. Obstetrics &amp; Gynecology. 2009; 114(5): 999-1007. doi: 10.1097/aog.0b013e3181bdce0a</mixed-citation><mixed-citation xml:lang="en">McClung M, Miller P, Recknor C, Mesenbrink P, Bucci-Rechtweg C, Benhamou C. Zoledronic Acid for the Prevention of Bone Loss in Postmenopausal Women With Low Bone Mass. Obstetrics &amp; Gynecology. 2009; 114(5): 999-1007. doi: 10.1097/aog.0b013e3181bdce0a</mixed-citation></citation-alternatives></ref><ref id="cit75"><label>75</label><citation-alternatives><mixed-citation xml:lang="ru">Langdahl B., Teglbjærg C., Ho P. et al. A 24-Month Study Evaluating the Efficacy and Safety of Denosumab for the Treatment of Men With Low Bone Mineral Density: Results From the ADAMO Trial. The Journal of Clinical Endocrinology &amp; Metabolism. 2015; 100(4): 1335-1342. doi: 10.1210/jc.2014-4079</mixed-citation><mixed-citation xml:lang="en">Langdahl B., Teglbjærg C., Ho P. et al. A 24-Month Study Evaluating the Efficacy and Safety of Denosumab for the Treatment of Men With Low Bone Mineral Density: Results From the ADAMO Trial. The Journal of Clinical Endocrinology &amp; Metabolism. 2015; 100(4): 1335-1342. doi: 10.1210/jc.2014-4079</mixed-citation></citation-alternatives></ref><ref id="cit76"><label>76</label><citation-alternatives><mixed-citation xml:lang="ru">Orwoll E., Teglbjærg C., Langdahl B. et al. A Randomized, Placebo-Controlled Study of the Effects of Denosumab for the Treatment of Men with Low Bone Mineral Density. The Journal of Clinical Endocrinology &amp; Metabolism. 2012; 97(9): 3161-3169. doi: 10.1210/jc.2012-1569</mixed-citation><mixed-citation xml:lang="en">Orwoll E., Teglbjærg C., Langdahl B. et al. A Randomized, Placebo-Controlled Study of the Effects of Denosumab for the Treatment of Men with Low Bone Mineral Density. The Journal of Clinical Endocrinology &amp; Metabolism. 2012; 97(9): 3161-3169. doi: 10.1210/jc.2012-1569</mixed-citation></citation-alternatives></ref><ref id="cit77"><label>77</label><citation-alternatives><mixed-citation xml:lang="ru">Gnant M., Pfeiler G., Dubsky P. et al. Adjuvant denosumab in breast cancer (ABCSG-18): a multicentre, randomised, double-blind, placebo-controlled trial. The Lancet. 2015; 386(9992): 433-443. doi: 10.1016/s0140-6736(15)60995-3</mixed-citation><mixed-citation xml:lang="en">Gnant M., Pfeiler G., Dubsky P. et al. Adjuvant denosumab in breast cancer (ABCSG-18): a multicentre, randomised, double-blind, placebo-controlled trial. The Lancet. 2015; 386(9992): 433-443. doi: 10.1016/s0140-6736(15)60995-3</mixed-citation></citation-alternatives></ref><ref id="cit78"><label>78</label><citation-alternatives><mixed-citation xml:lang="ru">McClung M. Inhibition of RANKL as a treatment for osteoporosis: Preclinical and early clinical studies. Current Osteoporosis Reports. 2006; 4(1): 28-33. doi: 10.1007/s11914-006-0012-7</mixed-citation><mixed-citation xml:lang="en">McClung M. Inhibition of RANKL as a treatment for osteoporosis: Preclinical and early clinical studies. Current Osteoporosis Reports. 2006; 4(1): 28-33. doi: 10.1007/s11914-006-0012-7</mixed-citation></citation-alternatives></ref><ref id="cit79"><label>79</label><citation-alternatives><mixed-citation xml:lang="ru">Miller P., Bolognese M., Lewiecki E. et al. Effect of denosumab on bone density and turnover in postmenopausal women with low bone mass after long-term continued, discontinued, and restarting of therapy: A randomized blinded phase 2 clinical trial. Bone. 2008; 43(2): 222-229. doi: 10.1016/j.bone.2008.04.007</mixed-citation><mixed-citation xml:lang="en">Miller P., Bolognese M., Lewiecki E. et al. Effect of denosumab on bone density and turnover in postmenopausal women with low bone mass after long-term continued, discontinued, and restarting of therapy: A randomized blinded phase 2 clinical trial. Bone. 2008; 43(2): 222-229. doi: 10.1016/j.bone.2008.04.007</mixed-citation></citation-alternatives></ref><ref id="cit80"><label>80</label><citation-alternatives><mixed-citation xml:lang="ru">Белая Ж.Е., Рожинская Л.Я. Новые направления в терапии остеопороза - применение моноклональных человеческих антител к RANKL (Деносумаб). // Остеопороз и Остеопатии. 2011; 2: 19-22</mixed-citation><mixed-citation xml:lang="en">Белая Ж.Е., Рожинская Л.Я. Новые направления в терапии остеопороза - применение моноклональных человеческих антител к RANKL (Деносумаб). // Остеопороз и Остеопатии. 2011; 2: 19-22</mixed-citation></citation-alternatives></ref><ref id="cit81"><label>81</label><citation-alternatives><mixed-citation xml:lang="ru">Brown J., Prince R., Deal C. et al. Comparison of the Effect of Denosumab and Alendronate on BMD and Biochemical Markers of Bone Turnover in Postmenopausal Women With Low Bone Mass: A Randomized, Blinded, Phase 3 Trial*. Journal of Bone and Mineral Research. 2009; 24(1): 153-161. doi: 10.1359/jbmr.0809010.</mixed-citation><mixed-citation xml:lang="en">Brown J., Prince R., Deal C. et al. Comparison of the Effect of Denosumab and Alendronate on BMD and Biochemical Markers of Bone Turnover in Postmenopausal Women With Low Bone Mass: A Randomized, Blinded, Phase 3 Trial*. Journal of Bone and Mineral Research. 2009; 24(1): 153-161. doi: 10.1359/jbmr.0809010.</mixed-citation></citation-alternatives></ref><ref id="cit82"><label>82</label><citation-alternatives><mixed-citation xml:lang="ru">Mandema J.W.1, Zheng J., Libanati C., Perez Ruixo J.J. Time course of bone mineral density changes with denosumab compared with other drugs in postmenopausal osteoporosis: a dose-response-based meta-analysis.J Clin Endocrinol Metab. 2014 Oct; 99(10): 3746-55. doi: 10.1210/jc.2013-3795. Epub 2014 Jun 10.</mixed-citation><mixed-citation xml:lang="en">Mandema J.W.1, Zheng J., Libanati C., Perez Ruixo J.J. Time course of bone mineral density changes with denosumab compared with other drugs in postmenopausal osteoporosis: a dose-response-based meta-analysis.J Clin Endocrinol Metab. 2014 Oct; 99(10): 3746-55. doi: 10.1210/jc.2013-3795. Epub 2014 Jun 10.</mixed-citation></citation-alternatives></ref><ref id="cit83"><label>83</label><citation-alternatives><mixed-citation xml:lang="ru">Choi N.K., Solomon D.H., Tsacogianis T.N., Landon J.E., Song H.J., Kim S.C. Comparative Safety and Effectiveness of Denosumab Versus Zoledronic Acid in Patients With Osteoporosis: A Cohort Study. J Bone Miner Res. 2016 Oct 13. doi: 10.1002/jbmr.3019. [Epub ahead of print]</mixed-citation><mixed-citation xml:lang="en">Choi N.K., Solomon D.H., Tsacogianis T.N., Landon J.E., Song H.J., Kim S.C. Comparative Safety and Effectiveness of Denosumab Versus Zoledronic Acid in Patients With Osteoporosis: A Cohort Study. J Bone Miner Res. 2016 Oct 13. doi: 10.1002/jbmr.3019. [Epub ahead of print]</mixed-citation></citation-alternatives></ref><ref id="cit84"><label>84</label><citation-alternatives><mixed-citation xml:lang="ru">Kendler D., Roux C., Benhamou C. et al. Effects of denosumab on bone mineral density and bone turnover in postmenopausal women transitioning from alendronate therapy. J Bone Miner Res. 2009; 25(1): 72-81. doi: 10.1359/jbmr.090716.</mixed-citation><mixed-citation xml:lang="en">Kendler D., Roux C., Benhamou C. et al. Effects of denosumab on bone mineral density and bone turnover in postmenopausal women transitioning from alendronate therapy. J Bone Miner Res. 2009; 25(1): 72-81. doi: 10.1359/jbmr.090716.</mixed-citation></citation-alternatives></ref><ref id="cit85"><label>85</label><citation-alternatives><mixed-citation xml:lang="ru">Tsai.J, Uihlein A., Burnett-Bowie S. et al. Comparative Effects of Teriparatide, Denosumab, and Combination Therapy on Peripheral Compartmental Bone Density, Microarchitecture, and Estimated Strength: the DATA-HRpQCT Study. J Bone Miner Res. 2014; 30(1): 39-45. doi: 10.1002/jbmr.2315.</mixed-citation><mixed-citation xml:lang="en">Tsai.J, Uihlein A., Burnett-Bowie S. et al. Comparative Effects of Teriparatide, Denosumab, and Combination Therapy on Peripheral Compartmental Bone Density, Microarchitecture, and Estimated Strength: the DATA-HRpQCT Study. J Bone Miner Res. 2014; 30(1): 39-45. doi: 10.1002/jbmr.2315.</mixed-citation></citation-alternatives></ref><ref id="cit86"><label>86</label><citation-alternatives><mixed-citation xml:lang="ru">Белая Ж.Е., Рожинская Л.Я. Анаболическая терапия остеопороза. Терипаратид: эффективность, безопасность и область применения. Остеопороз и остеопатии. 2013; 2: 32-40.</mixed-citation><mixed-citation xml:lang="en">Белая Ж.Е., Рожинская Л.Я. Анаболическая терапия остеопороза. Терипаратид: эффективность, безопасность и область применения. Остеопороз и остеопатии. 2013; 2: 32-40.</mixed-citation></citation-alternatives></ref><ref id="cit87"><label>87</label><citation-alternatives><mixed-citation xml:lang="ru">Gallagher J., Genant H., Crans G., Vargas S., Krege J. Teriparatide Reduces the Fracture Risk Associated with Increasing Number and Severity of Osteoporotic Fractures. The Journal of Clinical Endocrinology &amp; Metabolism. 2005; 90(3): 1583-1587. doi: 10.1210/jc.2004-0826.</mixed-citation><mixed-citation xml:lang="en">Gallagher J., Genant H., Crans G., Vargas S., Krege J. Teriparatide Reduces the Fracture Risk Associated with Increasing Number and Severity of Osteoporotic Fractures. The Journal of Clinical Endocrinology &amp; Metabolism. 2005; 90(3): 1583-1587. doi: 10.1210/jc.2004-0826.</mixed-citation></citation-alternatives></ref><ref id="cit88"><label>88</label><citation-alternatives><mixed-citation xml:lang="ru">Marcus R., Wang O., Satterwhite J., Mitlak B. The Skeletal Response to Teriparatide Is Largely Independent of Age, Initial Bone Mineral Density, and Prevalent Vertebral Fractures in Postmenopausal Women With Osteoporosis. J Bone Miner Res. 2003; 18(1): 18-23. doi: 10.1359/jbmr.2003.18.1.18.</mixed-citation><mixed-citation xml:lang="en">Marcus R., Wang O., Satterwhite J., Mitlak B. The Skeletal Response to Teriparatide Is Largely Independent of Age, Initial Bone Mineral Density, and Prevalent Vertebral Fractures in Postmenopausal Women With Osteoporosis. J Bone Miner Res. 2003; 18(1): 18-23. doi: 10.1359/jbmr.2003.18.1.18.</mixed-citation></citation-alternatives></ref><ref id="cit89"><label>89</label><citation-alternatives><mixed-citation xml:lang="ru">Orwoll E., Scheele W., Paul S. et al. The Effect of Teriparatide [Human Parathyroid Hormone (1-34)] Therapy on Bone Density in Men With Osteoporosis. J Bone Miner Res. 2003; 18(1): 9-17. doi: 10.1359/jbmr.2003.18.1.9.</mixed-citation><mixed-citation xml:lang="en">Orwoll E., Scheele W., Paul S. et al. The Effect of Teriparatide [Human Parathyroid Hormone (1-34)] Therapy on Bone Density in Men With Osteoporosis. J Bone Miner Res. 2003; 18(1): 9-17. doi: 10.1359/jbmr.2003.18.1.9.</mixed-citation></citation-alternatives></ref><ref id="cit90"><label>90</label><citation-alternatives><mixed-citation xml:lang="ru">Saag K., Shane E., Boonen S. et al. Teriparatide or Alendronate in Glucocorticoid-Induced Osteoporosis. N Engl J Med. 2007 Nov 15; 357(20): 2028-39 DOI: 10.1056/NEJMoa071408</mixed-citation><mixed-citation xml:lang="en">Saag K., Shane E., Boonen S. et al. Teriparatide or Alendronate in Glucocorticoid-Induced Osteoporosis. N Engl J Med. 2007 Nov 15; 357(20): 2028-39 DOI: 10.1056/NEJMoa071408</mixed-citation></citation-alternatives></ref><ref id="cit91"><label>91</label><citation-alternatives><mixed-citation xml:lang="ru">Saag K., Zanchetta J., Devogelaer J. et al. Effects of teriparatide versus alendronate for treating glucocorticoid-induced osteoporosis: Thirty-six-month results of a randomized, double-blind, controlled trial. Arthritis &amp; Rheumatism. 2009; 60(11): 3346-3355. doi: 10.1002/art.24879</mixed-citation><mixed-citation xml:lang="en">Saag K., Zanchetta J., Devogelaer J. et al. Effects of teriparatide versus alendronate for treating glucocorticoid-induced osteoporosis: Thirty-six-month results of a randomized, double-blind, controlled trial. Arthritis &amp; Rheumatism. 2009; 60(11): 3346-3355. doi: 10.1002/art.24879</mixed-citation></citation-alternatives></ref><ref id="cit92"><label>92</label><citation-alternatives><mixed-citation xml:lang="ru">Body J., Gaich G., Scheele W. et al. A Randomized Double-Blind Trial to Compare the Efficacy of Teriparatide [Recombinant Human Parathyroid Hormone (1-34)] with Alendronate in Postmenopausal Women with Osteoporosis. The Journal of Clinical Endocrinology &amp; Metabolism. 2002; 87(10): 4528-4535. doi: 10.1210/jc.2002-020334.</mixed-citation><mixed-citation xml:lang="en">Body J., Gaich G., Scheele W. et al. A Randomized Double-Blind Trial to Compare the Efficacy of Teriparatide [Recombinant Human Parathyroid Hormone (1-34)] with Alendronate in Postmenopausal Women with Osteoporosis. The Journal of Clinical Endocrinology &amp; Metabolism. 2002; 87(10): 4528-4535. doi: 10.1210/jc.2002-020334.</mixed-citation></citation-alternatives></ref><ref id="cit93"><label>93</label><citation-alternatives><mixed-citation xml:lang="ru">Hadji P, Zanchetta J, Russo L et al. Effect of teriparatide compared with risedronate on back pain and incident vertebral fractures in postmenopausal women with osteoporotic vertebral fractures. Bone. 2011; 48: S82-S83. doi: 10.1016/j.bone.2011.03.108.</mixed-citation><mixed-citation xml:lang="en">Hadji P, Zanchetta J, Russo L et al. Effect of teriparatide compared with risedronate on back pain and incident vertebral fractures in postmenopausal women with osteoporotic vertebral fractures. Bone. 2011; 48: S82-S83. doi: 10.1016/j.bone.2011.03.108.</mixed-citation></citation-alternatives></ref><ref id="cit94"><label>94</label><citation-alternatives><mixed-citation xml:lang="ru">Miller P.D., Shergy W.J., Body J., Chen P., Rohe M.E, Krege J.H.: Longterm reduction of back pain risk in women with osteoporosis treated with teriparatide compared with alendronate. J Rheumatology. 2005; 32: 1556-1562.</mixed-citation><mixed-citation xml:lang="en">Miller P.D., Shergy W.J., Body J., Chen P., Rohe M.E, Krege J.H.: Longterm reduction of back pain risk in women with osteoporosis treated with teriparatide compared with alendronate. J Rheumatology. 2005; 32: 1556-1562.</mixed-citation></citation-alternatives></ref><ref id="cit95"><label>95</label><citation-alternatives><mixed-citation xml:lang="ru">European Medicines Agency Press Office. EMEA recommends changes in the product Information for Protelos/ Osseor due to the risk of severe hypersensitivity reactions. EMEA/417458/2007</mixed-citation><mixed-citation xml:lang="en">European Medicines Agency Press Office. EMEA recommends changes in the product Information for Protelos/ Osseor due to the risk of severe hypersensitivity reactions. EMEA/417458/2007</mixed-citation></citation-alternatives></ref><ref id="cit96"><label>96</label><citation-alternatives><mixed-citation xml:lang="ru">European Medicines Agency: Recommendation to restrict the use of Protelos/Osseor (strontium ranelate) 25 April 2013 EMA/258269/2013</mixed-citation><mixed-citation xml:lang="en">European Medicines Agency: Recommendation to restrict the use of Protelos/Osseor (strontium ranelate) 25 April 2013 EMA/258269/2013</mixed-citation></citation-alternatives></ref><ref id="cit97"><label>97</label><citation-alternatives><mixed-citation xml:lang="ru">European Medicines Agency: Protelos/Osseor (strontium ranelate) to remain available but with futher restrictions 15 April 2014 EMA 235924/2014</mixed-citation><mixed-citation xml:lang="en">European Medicines Agency: Protelos/Osseor (strontium ranelate) to remain available but with futher restrictions 15 April 2014 EMA 235924/2014</mixed-citation></citation-alternatives></ref><ref id="cit98"><label>98</label><citation-alternatives><mixed-citation xml:lang="ru">Lee H., Lie D., Lim K., Thirumoorthy T., Pang S. Strontium ranelate-induced toxic epidermal necrolysis in a patient with post-menopausal osteoporosis. Osteoporosis International. 2008; 20(1): 161-162. doi: 10.1007/s00198-008-0677-0.</mixed-citation><mixed-citation xml:lang="en">Lee H., Lie D., Lim K., Thirumoorthy T., Pang S. Strontium ranelate-induced toxic epidermal necrolysis in a patient with post-menopausal osteoporosis. Osteoporosis International. 2008; 20(1): 161-162. doi: 10.1007/s00198-008-0677-0.</mixed-citation></citation-alternatives></ref><ref id="cit99"><label>99</label><citation-alternatives><mixed-citation xml:lang="ru">Tan K.-W., Wang Y.-S., Tay Y.-K.: Stevens-Johnson syndrome due to strontium ranelate. Annals Academy of Medicine. 2011(40): 10-11.</mixed-citation><mixed-citation xml:lang="en">Tan K.-W., Wang Y.-S., Tay Y.-K.: Stevens-Johnson syndrome due to strontium ranelate. Annals Academy of Medicine. 2011(40): 10-11.</mixed-citation></citation-alternatives></ref><ref id="cit100"><label>100</label><citation-alternatives><mixed-citation xml:lang="ru">Cacoub P., Descamps V., Meyer O., Speirs C., Belissa-Mathiot P., Musette P. Drug rash with eosinophilia and systemic symptoms (DRESS) in patients receiving strontium ranelate. Osteoporosis International. 2013; 24(5): 1751-1757. doi: 10.1007/s00198-013-2265-1</mixed-citation><mixed-citation xml:lang="en">Cacoub P., Descamps V., Meyer O., Speirs C., Belissa-Mathiot P., Musette P. Drug rash with eosinophilia and systemic symptoms (DRESS) in patients receiving strontium ranelate. Osteoporosis International. 2013; 24(5): 1751-1757. doi: 10.1007/s00198-013-2265-1</mixed-citation></citation-alternatives></ref><ref id="cit101"><label>101</label><citation-alternatives><mixed-citation xml:lang="ru">Adler R., El-Hajj Fuleihan G., Bauer D. et al. Managing Osteoporosis in Patients on Long-Term Bisphosphonate Treatment: Report of a Task Force of the American Society for Bone and Mineral Research. J Bone Miner Res. 2016; 31(1): 16-35. doi: 10.1002/jbmr.2708</mixed-citation><mixed-citation xml:lang="en">Adler R., El-Hajj Fuleihan G., Bauer D. et al. Managing Osteoporosis in Patients on Long-Term Bisphosphonate Treatment: Report of a Task Force of the American Society for Bone and Mineral Research. J Bone Miner Res. 2016; 31(1): 16-35. doi: 10.1002/jbmr.2708</mixed-citation></citation-alternatives></ref><ref id="cit102"><label>102</label><citation-alternatives><mixed-citation xml:lang="ru">Bone H.G., Hosking D., Devogelaer J.P., Tucci J.R., Emkey R.D., Tonino R.P., Rodriguez-Portales J.A., Downs R.W., Gupta J., Santora A.C., Liberman U.A.; AlendronatePhase III Osteoporosis Treatment Study GroupTen years' experience with alendronate for osteoporosis in postmenopausal women.N Engl J Med. 2004 Mar 18; 350(12): 1189-99</mixed-citation><mixed-citation xml:lang="en">Bone H.G., Hosking D., Devogelaer J.P., Tucci J.R., Emkey R.D., Tonino R.P., Rodriguez-Portales J.A., Downs R.W., Gupta J., Santora A.C., Liberman U.A.; AlendronatePhase III Osteoporosis Treatment Study GroupTen years' experience with alendronate for osteoporosis in postmenopausal women.N Engl J Med. 2004 Mar 18; 350(12): 1189-99</mixed-citation></citation-alternatives></ref><ref id="cit103"><label>103</label><citation-alternatives><mixed-citation xml:lang="ru">Bone H.G., Brandi M.L., Brown J.P., Chapurlat R., Cummings S.R., Czerwinski E., Fahrleitner-Pammer A., Kendler D.L., Lippuner K., Reginster J.-Y., Roux C., Vittinghoff E., Daizadeh N.S., Wang A., Dakin P., Wagman R.B., Papapoulos S. Ten Years of Denosumab treatment in postmenopausal women with osteoporosis: results from the FREEDOM extension trial. ASBMR 2015 Abstract (Pub ID: 057237)</mixed-citation><mixed-citation xml:lang="en">Bone H.G., Brandi M.L., Brown J.P., Chapurlat R., Cummings S.R., Czerwinski E., Fahrleitner-Pammer A., Kendler D.L., Lippuner K., Reginster J.-Y., Roux C., Vittinghoff E., Daizadeh N.S., Wang A., Dakin P., Wagman R.B., Papapoulos S. Ten Years of Denosumab treatment in postmenopausal women with osteoporosis: results from the FREEDOM extension trial. ASBMR 2015 Abstract (Pub ID: 057237)</mixed-citation></citation-alternatives></ref><ref id="cit104"><label>104</label><citation-alternatives><mixed-citation xml:lang="ru">Brown J., Roux C., Törring O. et al. Discontinuation of denosumab and associated fracture incidence: Analysis from the Fracture Reduction Evaluation of Denosumab in Osteoporosis Every 6 Months (FREEDOM) Trial. J Bone Miner Res. 2013; 28(4): 746-752. doi: 10.1002/jbmr.1808.</mixed-citation><mixed-citation xml:lang="en">Brown J., Roux C., Törring O. et al. Discontinuation of denosumab and associated fracture incidence: Analysis from the Fracture Reduction Evaluation of Denosumab in Osteoporosis Every 6 Months (FREEDOM) Trial. J Bone Miner Res. 2013; 28(4): 746-752. doi: 10.1002/jbmr.1808.</mixed-citation></citation-alternatives></ref><ref id="cit105"><label>105</label><citation-alternatives><mixed-citation xml:lang="ru">Popp A., Zysset P., Lippuner K. Rebound-associated vertebral fractures after discontinuation of denosumab - from clinic and biomechanics. Osteoporosis International. 2015; 27(5): 1917-1921. doi: 10.1007/s00198-015-3458-6.</mixed-citation><mixed-citation xml:lang="en">Popp A., Zysset P., Lippuner K. Rebound-associated vertebral fractures after discontinuation of denosumab - from clinic and biomechanics. Osteoporosis International. 2015; 27(5): 1917-1921. doi: 10.1007/s00198-015-3458-6.</mixed-citation></citation-alternatives></ref><ref id="cit106"><label>106</label><citation-alternatives><mixed-citation xml:lang="ru">Koldkjær Sөlling A, Harslөf T., Kaal A., Rejnmark L., Langdahl B. Hypercalcemia after discontinuation of longterm denosumab treatment. Osteoporosis International. 2016. doi: 10.1007/s00198-016-3535-5 № 3/2016 Остеопороз и остеопатии</mixed-citation><mixed-citation xml:lang="en">Koldkjær Sөlling A, Harslөf T., Kaal A., Rejnmark L., Langdahl B. Hypercalcemia after discontinuation of longterm denosumab treatment. Osteoporosis International. 2016. doi: 10.1007/s00198-016-3535-5 № 3/2016 Остеопороз и остеопатии</mixed-citation></citation-alternatives></ref><ref id="cit107"><label>107</label><citation-alternatives><mixed-citation xml:lang="ru">Diez-Perez A., Adachi J.D., Agnusdei D., Bilezikian J.P., Compston J.E., Cummings S.R., Eastell R., Eriksen E.F., Gonzales-Macies J., Liberman U.A., Wahl D.A., Seeman E., Kanis J.A., Cooper C.: Treatment failure in osteoporosis. Osteoporosis Int. 2012; (23): 2769-2774.</mixed-citation><mixed-citation xml:lang="en">Diez-Perez A., Adachi J.D., Agnusdei D., Bilezikian J.P., Compston J.E., Cummings S.R., Eastell R., Eriksen E.F., Gonzales-Macies J., Liberman U.A., Wahl D.A., Seeman E., Kanis J.A., Cooper C.: Treatment failure in osteoporosis. Osteoporosis Int. 2012; (23): 2769-2774.</mixed-citation></citation-alternatives></ref><ref id="cit108"><label>108</label><citation-alternatives><mixed-citation xml:lang="ru">Harris S.T., Watts N.B., Genant H.K. et al. Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial. Vertebral Efficacy With Risedronate Therapy (VERT) Study Group. JAMA. 1999; 282: 1344-1352.</mixed-citation><mixed-citation xml:lang="en">Harris S.T., Watts N.B., Genant H.K. et al. Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial. Vertebral Efficacy With Risedronate Therapy (VERT) Study Group. JAMA. 1999; 282: 1344-1352.</mixed-citation></citation-alternatives></ref><ref id="cit109"><label>109</label><citation-alternatives><mixed-citation xml:lang="ru">Reginster J., Minne H., Sorensen O. et al. Randomized Trial of the Effects of Risedronate on Vertebral Fractures in Women with Established Postmenopausal Osteoporosis. Osteoporosis International. 2000; 11(1): 83-91. doi: 10.1007/s001980050010.</mixed-citation><mixed-citation xml:lang="en">Reginster J., Minne H., Sorensen O. et al. Randomized Trial of the Effects of Risedronate on Vertebral Fractures in Women with Established Postmenopausal Osteoporosis. Osteoporosis International. 2000; 11(1): 83-91. doi: 10.1007/s001980050010.</mixed-citation></citation-alternatives></ref><ref id="cit110"><label>110</label><citation-alternatives><mixed-citation xml:lang="ru">Ettinger B., Black D., Mitlak B. et al. Reduction of Vertebral Fracture Risk in Postmenopausal Women With Osteoporosis Treated With Raloxifene: Results From a 3-Year Randomized Clinical Trial. Obstetrical &amp; Gynecological Survey. 2000; 55(1): 39. doi: 10.1097/00006254-200001000-00021</mixed-citation><mixed-citation xml:lang="en">Ettinger B., Black D., Mitlak B. et al. Reduction of Vertebral Fracture Risk in Postmenopausal Women With Osteoporosis Treated With Raloxifene: Results From a 3-Year Randomized Clinical Trial. Obstetrical &amp; Gynecological Survey. 2000; 55(1): 39. doi: 10.1097/00006254-200001000-00021</mixed-citation></citation-alternatives></ref><ref id="cit111"><label>111</label><citation-alternatives><mixed-citation xml:lang="ru">Neer R., Arnaud C., Zanchetta J. et al. Effect of Parathyroid Hormone (1-34) on Fractures and Bone Mineral Density in Postmenopausal Women With Osteoporosis. N Engl J Med. 2001 May 10; 344(19): 1434-41 DOI: 10.1056/NEJM200105103441904</mixed-citation><mixed-citation xml:lang="en">Neer R., Arnaud C., Zanchetta J. et al. Effect of Parathyroid Hormone (1-34) on Fractures and Bone Mineral Density in Postmenopausal Women With Osteoporosis. N Engl J Med. 2001 May 10; 344(19): 1434-41 DOI: 10.1056/NEJM200105103441904</mixed-citation></citation-alternatives></ref><ref id="cit112"><label>112</label><citation-alternatives><mixed-citation xml:lang="ru">Chesnut C., Skag A., Christiansen C. et al. Effects of Oral Ibandronate Administered Daily or Intermittently on Fracture Risk in Postmenopausal Osteoporosis. J Bone Miner Res. 2004; 19(8): 1241-1249. doi: 10.1359/jbmr.040325.</mixed-citation><mixed-citation xml:lang="en">Chesnut C., Skag A., Christiansen C. et al. Effects of Oral Ibandronate Administered Daily or Intermittently on Fracture Risk in Postmenopausal Osteoporosis. J Bone Miner Res. 2004; 19(8): 1241-1249. doi: 10.1359/jbmr.040325.</mixed-citation></citation-alternatives></ref><ref id="cit113"><label>113</label><citation-alternatives><mixed-citation xml:lang="ru">Meunier P., Roux C., Seeman E. et al. The Effects of Strontium Ranelate on the Risk of Vertebral Fracture in Women With Postmenopausal Osteoporosis. N Engl J Med. 2004 Jan 29; 350(5): 459-68 DOI: 10.1056/NEJMoa022436</mixed-citation><mixed-citation xml:lang="en">Meunier P., Roux C., Seeman E. et al. The Effects of Strontium Ranelate on the Risk of Vertebral Fracture in Women With Postmenopausal Osteoporosis. N Engl J Med. 2004 Jan 29; 350(5): 459-68 DOI: 10.1056/NEJMoa022436</mixed-citation></citation-alternatives></ref><ref id="cit114"><label>114</label><citation-alternatives><mixed-citation xml:lang="ru">Gaal J., Bender T., Varga J. et al. Overcoming resistance to bisphosphonates through the administration of alfacalcidol: results of a 1-year, open follow-up study. Rheumatol Int. 2009; 30(1): 25-31. doi: 10.1007/s00296-009-0892-9.</mixed-citation><mixed-citation xml:lang="en">Gaal J., Bender T., Varga J. et al. Overcoming resistance to bisphosphonates through the administration of alfacalcidol: results of a 1-year, open follow-up study. Rheumatol Int. 2009; 30(1): 25-31. doi: 10.1007/s00296-009-0892-9.</mixed-citation></citation-alternatives></ref><ref id="cit115"><label>115</label><citation-alternatives><mixed-citation xml:lang="ru">British Orthopaedic Association and British Geriatrics Society. The care of patients with fragility fracture. 2007: 15-50.</mixed-citation><mixed-citation xml:lang="en">British Orthopaedic Association and British Geriatrics Society. The care of patients with fragility fracture. 2007: 15-50.</mixed-citation></citation-alternatives></ref><ref id="cit116"><label>116</label><citation-alternatives><mixed-citation xml:lang="ru">Griffiths R., Alper J., Beckingsale A. et al. Management of proximal femoral fractures 2011. Anaesthesia. 2011; 67(1): 85-98. doi: 10.1111/j.1365-2044.2011.06957.x.</mixed-citation><mixed-citation xml:lang="en">Griffiths R., Alper J., Beckingsale A. et al. Management of proximal femoral fractures 2011. Anaesthesia. 2011; 67(1): 85-98. doi: 10.1111/j.1365-2044.2011.06957.x.</mixed-citation></citation-alternatives></ref><ref id="cit117"><label>117</label><citation-alternatives><mixed-citation xml:lang="ru">Загородний Н.В., Голухов Г.Н., Волна А.А. и др. Диагностика и лечение переломов проксимального отдела бедра у лиц пожилого и старческого возраста. Метод. Рекомендации. Москва, РУДН, 2012.</mixed-citation><mixed-citation xml:lang="en">Загородний Н.В., Голухов Г.Н., Волна А.А. и др. Диагностика и лечение переломов проксимального отдела бедра у лиц пожилого и старческого возраста. Метод. Рекомендации. Москва, РУДН, 2012.</mixed-citation></citation-alternatives></ref><ref id="cit118"><label>118</label><citation-alternatives><mixed-citation xml:lang="ru">Roche J. Effect of comorbidities and postoperative complications on mortality after hip fracture in elderly people: prospective observational cohort study. BMJ. 2005; 331(7529): 1374-0. doi: 10.1136/bmj.38643.663843.55.</mixed-citation><mixed-citation xml:lang="en">Roche J. Effect of comorbidities and postoperative complications on mortality after hip fracture in elderly people: prospective observational cohort study. BMJ. 2005; 331(7529): 1374-0. doi: 10.1136/bmj.38643.663843.55.</mixed-citation></citation-alternatives></ref><ref id="cit119"><label>119</label><citation-alternatives><mixed-citation xml:lang="ru">Kates S., Mendelson D., Friedman S. Co-managed care for fragility hip fractures (Rochester model). Osteoporosis International. 2010; 21(S4): 621-625. doi: 10.1007/s00198-010-1417-9.</mixed-citation><mixed-citation xml:lang="en">Kates S., Mendelson D., Friedman S. Co-managed care for fragility hip fractures (Rochester model). Osteoporosis International. 2010; 21(S4): 621-625. doi: 10.1007/s00198-010-1417-9.</mixed-citation></citation-alternatives></ref><ref id="cit120"><label>120</label><citation-alternatives><mixed-citation xml:lang="ru">Agnelli G. Prevention of Venous Thromboembolism in Surgical Patients. Circulation. 2004; 110(24_suppl_1): IV-4-IV-12. doi: 10.1161/01.cir.0000150639.98514.6c.</mixed-citation><mixed-citation xml:lang="en">Agnelli G. Prevention of Venous Thromboembolism in Surgical Patients. Circulation. 2004; 110(24_suppl_1): IV-4-IV-12. doi: 10.1161/01.cir.0000150639.98514.6c.</mixed-citation></citation-alternatives></ref><ref id="cit121"><label>121</label><citation-alternatives><mixed-citation xml:lang="ru">Leonardsson O., Rolfson O., Hommel A., Garellick G., Âkesson K., Rogmark C. Patient-Reported Outcome After Displaced Femoral Neck Fracture. The Journal of Bone and Joint Surgery (American). 2013; 95(18): 1693. doi: 10.2106/jbjs.l.00836.</mixed-citation><mixed-citation xml:lang="en">Leonardsson O., Rolfson O., Hommel A., Garellick G., Âkesson K., Rogmark C. Patient-Reported Outcome After Displaced Femoral Neck Fracture. The Journal of Bone and Joint Surgery (American). 2013; 95(18): 1693. doi: 10.2106/jbjs.l.00836.</mixed-citation></citation-alternatives></ref><ref id="cit122"><label>122</label><citation-alternatives><mixed-citation xml:lang="ru">Silverman S.L., Kupperman E.S., Bukata S.V., Members of IOF Fracture Working Group Fracture healing: a consensus report from the International Osteoporosis Foundation Fracture Working Group Osteoporos Int (2016) 27: 2197-2206 DOI 10.1007/s00198-016-3513-y</mixed-citation><mixed-citation xml:lang="en">Silverman S.L., Kupperman E.S., Bukata S.V., Members of IOF Fracture Working Group Fracture healing: a consensus report from the International Osteoporosis Foundation Fracture Working Group Osteoporos Int (2016) 27: 2197-2206 DOI 10.1007/s00198-016-3513-y</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
