porozendoОстеопороз и остеопатииOsteoporosis and Bone Diseases2072-26802311-0716Endocrinology Research Centre10.14341/osteo2016337-40porozendo-9207Research ArticleСтатьиArticlesКЛИНИЧЕСКИЙ СЛУЧАЙ ПРИМЕНЕНИЯ ТЕРИПАРАТИДА ДЛЯ ЛЕЧЕНИЯ ПОСЛЕОПЕРАЦИОННОГО ГИПОПАРАТИРЕОЗА С НЕКОНТРОЛИРУЕМОЙ ГИПОКАЛЬЦИЕМИЕЙ В СОЧЕТАНИИ С ТЯЖЕЛЫМ ОСТЕОПОРОЗОМCLINICAL CASE OF TERIPARATIDE USE FOR THE TREATMENT OF POSTOPERATIVE HYPOPARATHYROIDISM WITH UNCONTROLLED HYPOCALCEMIA COMBINED WITH SEVERE OSTEOPOROSISГребенниковаТ АGrebennikovaT A

научный сотрудник отделения нейроэндокринологии и остеопатий

-ЛаринаИ ИLarinaI I

ординатор отделения нейроэндокринологии и остеопатий

-БелаяЖ ЕBelayaZh E

зав.отделением нейроэндокринологии и остеопатий, д.м.н.

-РожинскаяЛ ЯRozhinskayaL Y

главный научный сотрудник отделения нейроэндокринологии и остеопатий, д.м.н., профессор

-ФГБУ «Эндокринологический научный центр», Минздрава РФ201615122016193№3 (2016)3740Copyright © Гребенникова Т.А., Ларина И.И., Белая Ж.Е., Рожинская Л.Я., 20162016Гребенникова Т.А., Ларина И.И., Белая Ж.Е., Рожинская Л.Я.Grebennikova T.A., Larina I.I., Belaya Z.E., Rozhinskaya L.Y.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.osteo-endojournals.ru/jour/article/view/9207

Развитие послеоперационного гипопаратиреоза представляет собой наиболее часто встречающееся осложнение тиреоидэктомии и радикальных оперативных вмешательств в области шеи. Гипопаратиреоз характеризуется развитием гипокальциемии, недостаточностью паратгормона (ПТГ) и нарушением ремоделирования костной ткани. Традиционное лечение послеоперационного гипопаратиреоза заключается в компенсации гипокальциемии пероральными препаратами кальция и витамина D. Однако у части пациентов не удается достичь референсных значений уровня кальция на фоне данной терапии. Мы представляем описание клинического случая лечения послеоперационного гипопаратиреоза с выраженной клинической картиной на фоне трудно корригируемой гипокальциемии препаратом рекомбинантного человеческого гормона ПТГ 1-34 - терипаратида.

The development of postsurgical hypoparathyroidism is the most frequent complication of thyroidectomy and radical surgical procedures on the neck. Hypoparathyroidism is a disorder characterized by hypocalcemia, parathyroid hormone (PTH) deficiency, and abnormal bone remodeling. Standard treatment of hypoparathyroidism consists of oral calcium and active forms of vitamin D. However, some patients fail to achieve the normalization of calcium levels with this therapy. We present a clinical case of postsurgical hypoparathyroidism with severe clinical presentation of hypocalcaemia treated with recombinant human PTH 1-34 - teriparatide.

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The authors declare that there are no conflicts of interest present.