Preview

Osteoporosis and Bone Diseases

Advanced search

FROM REPLICATIVE SENESCENCE TO MICRORNA BASED DIAGNOSTICS OF AGE-ASSOCIATED DISEASES

https://doi.org/10.14341/osteo201615-7

About the Authors

Matthias Hackl
University of Natural Resources and Life Sciences; TAmiRNA GmbH
Department of Biotechnology


Syliva Weilner
University of Natural Resources and Life Sciences; TAmiRNA GmbH
Department of Biotechnology


Ursula Heilmayer
University of California San Francisco
Musculoskeletal Quantitative Imaging Research Group, Department of Radiology & Biomedical Imaging


Susanna Skalicky
TAmiRNA GmbH


Fabian Schröder
Austrian Institute of Technology
Department of Molecular Diagnostics


Elisabeth Schraml
University of Natural Resources and Life Sciences
Department of Biotechnology


Klemens Vierlinger
Austrian Institute of Technology
Department of Molecular Diagnostics


Thomas Link
University of California San Francisco
Musculoskeletal Quantitative Imaging Research Group, Department of Radiology & Biomedical Imaging


Johannes Grillari
University of Natural Resources and Life Sciences; TAmiRNA GmbH
Department of Biotechnology


References

1. Erusalimsky JD & Kurz DJ (2006) Endothelial cell senescence. Handb Exp Pharmacol, 213-248. Available at: http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrie ve&db=PubMed&dopt=Citation&list_uids=17001772.

2. Jing D, Hao J, Shen Y, Tang G, Li M-L, Huang S-H & Zhao Z-H (2015) The role of microRNAs in bone remodeling. J Oral Sci 7, 131-143. Available at: http:// dx.doi.org/10.1038/ijos.2015.22n10.1038/ijos.2015.22.

3. Lian JB, Stein GS, Wijnen AJ Van, Stein JL, Hassan MQ & Gaur T (2012) MicroRNA control of bone formation and homeostasis. Nat. Rev. Endocrinol. 8, 212-227. Available at: http://dx.doi.org/10.1038/nrendo.2011.234.

4. Lopez-Otin C, Blasco MA, Partridge L, Serrano M & Kroemer G (2013) The hallmarks of aging. Cell 153, 1194-217. Available at: http://www.pubmedcentral.nih. gov/articlerender.fcgi?artid=3836174&tool=pmcentrez&re ndertype=abstract [Accessed July 10, 2014]

5. Rando TA (2006) Stem cells, ageing and the quest for immortality. Nature 441, 1080-1086. Available at: http://www.ncbi.nlm.nih.gov/entrez/query. fcgi?cmd=Retrie ve&db=PubMed&dopt=Citation&list_uids=16810243.

6. Ratajczak MZ, Zuba-Surma EK, Machalinski B & Kucia M (2007) Bone-marrow-derived stem cells--our key to longevity? J Appl Genet 48, 307-319. Available at: http:// www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&d b=PubMed&dopt=Citation&list_uids=17998587.

7. Weilner S, Grillari-Voglauer R, Redl H, Grillari J & Nau T (2015) The role of microRNAs in cellular senescence and age-related conditions of cartilage and bone. Acta Orthop. 86, 92-9. Available at: http://www.pubmedcentral. nih.gov/articlerender.fcgi?artid=4366666&tool=pmcentrez &rendertype=abstract [Accessed January 26, 2016].

8. Weilner S, Keider V, Winter M, Harreither E, Salzer B, Weiss F, Schraml E, Messner P, Pietschmann P, Hildner F, Gabriel C, Redl H, Grillari-Voglauer R & Grillari J (2016) Vesicular Galectin-3 levels decrease with donor age and contribute to the reduced osteo-inductive potential of human plasma derived extracellular vesicles. Aging (Albany. NY). 8, 16-33. Available at: http://www.ncbi.nlm. nih.gov/pubmed/26752347 [Accessed March 7, 2016].

9. Weilner S, Schraml E, Wieser M, Messner P, Schneider K, Wassermann K, Micutkova L, Fortschegger K, Maier AB, Westendorp R, Resch H, Wolbank S, Redl H, Jansen-Dürr P, Pietschmann P, Grillari-Voglauer R & Grillari J (2016) Secreted microvesicular miR-31 inhibits osteogenic differentiation of mesenchymal stem cells. Aging Cell, 1-11. Available at: http://doi.wiley.com/10.1111/acel.12484

10. Weilner S, Skalicky S, Salzer B, Keider V, Wagner M, Hildner F, Gabriel C, Dovjak P, Pietschmann P, Grillari-Voglauer R, Grillari J & Hackl M (2015) Differentially circulating miRNAs after recent osteoporotic fractures can influence osteogenic differentiation. Bone 79, 43-51. Available at: http://www.ncbi.nlm.nih.gov/ pubmed/26026730 [Accessed February 16, 2016]


Review

For citations:


Hackl M., Weilner S., Heilmayer U., Skalicky S., Schröder F., Schraml E., Vierlinger K., Link T., Grillari J. FROM REPLICATIVE SENESCENCE TO MICRORNA BASED DIAGNOSTICS OF AGE-ASSOCIATED DISEASES. Osteoporosis and Bone Diseases. 2016;19(1):5-7. (In Russ.) https://doi.org/10.14341/osteo201615-7

Views: 357


ISSN 2072-2680 (Print)
ISSN 2311-0716 (Online)