Massive osteolysis - gorham-stout syndrome
https://doi.org/10.14341/osteo2011127-32
Abstract
The paper provides a detailed description of the two cases of one of the rarest diseases - Gorham-Stout syndrome. This syndrome is accompanied by the massive osteolysis of various sites of a bone tissue. The literary review is done. The isolated osteolysis of the separate bone parts is a non-malignant process, and it goes without abnormalities of its functions. The combination of osteolysis with chylothorax is an unfavorable process. The treatment of this disease is possible only by calcitonin or bisphosphonates.
About the Authors
E. N. OttevaT. Yu. Kocherova
E. V. Shepichev
E. N. Otteva
T. Yu. Kocherova
E. V. Shepichev
References
1. Jackson J.B.S. A boneless arm. Boston Med Surg J 1838;18:368-9.
2. Jackson J.B.S. Absorption of the humerus after fracture. Boston Med Surg J 1872;10:245-7.
3. Gorham L.W., Stout A.P.. Massive osteolysis (acute spontaneous absorption of bone, phantom bone, disappearing bone): its relation to hemangiomatosis. J Bone Joint Surg [Am] 1955;37-A:985-1004.
4. Gowin W., Rahmanzadeh R. Radiologic diagnosis of massive idiopathic osteolysis (Gorham-Stout Syndrome). Rontgenpraxis 1985; 38:128-34.
5. Horst M., Zsernaviczky J., Delling G. A rare case of so-called idiopathic osteolysis associated with a lymphangioma of the fibula. Z Orthop 1979; 117:88-95.
6. Flörchinger A., Bottger E., Claass-Bottger F., Georgi M., Harms J. Gorham Stout syndrome of the spine: case report and review o literature. Rofo-Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr 1998; 168:68-76.
7. Tilling G., Skobowytsh B. Disappearing bone disease, Morbus Gorham: report of a case. Acta Orthop Scand 1968; 39:398-406.
8. Johnson P.M., McClure J.G. Observations of massive osteolysis: a review of the literature and report of a case. Radiology 1958; 71:28-42.
9. Thompson J.S., Schurman D.J. Massive osteolysis: case report and review of the literature. Clin Orthop 1974;103:206-11.
10. Gorham L.W., Wright A.W., Schultz H.H., Maxon F.C. Disappearing bones: a rare form of massive osteolysis: report of 2 cases, autopsy findings. Am J Med 1954;17:674-82
11. Knoch H.-G. Die Gorhamsche Krankheit aus klinischer Sicht. Zentralbl Chir 1963;18:674-83.
12. Young J.W., Galbraith M., Cunningham J., et al. Progressive vertebral collapse in diffuse angiomatosis. Metab Bone Dis Relat Res 1983;5:53-60.
13. Heyden G., Kindblom L.-G., Nielsen J.M. Disappearing bone disease: a clinical and histological study. J Bone Joint Surg [Am] 1977; 59-A:57-61.
14. Spieth M.E., Greenspan A, Forrester D.M., et al. Gorham's disease of the radius: radiographic, scintigraphic, and MRI findings with pathologic correlation: a case report and review of the literature. Skeletal Radiol 1997; 26:659-63.
15. Kery L., Wouters H.W.. Massive osteolysis: report of two cases. J Bone Joint Surg [Br] 1970; 52-B:452-9
16. Burkhard O., Beyer J., Schrezenmeir J., Brunier A.,Delling G. A case of idiopathic multicentric osteolysis. Med Klin 1989;84:364-8.
17. Milner S.M., Baker S.L.. Disappearing bones. J Bone Joint Surg [Br] 1958;40- B:502-13.
18. Chambers T.J. The cellular basis of bone resorption. Clin Orthop 1980;151: 283-93
19. Handl-Zeller L., Hohenberg G. Radiotherapy of Morbus Gorham-Stout: the biological value of low irradiation dose. Br J Radiol 1990;63:206-8.
20. Dunbar S.F., Rosenberg A., Mankin H., Rosenthal D., Suit H.D. Gorham's massive osteolysis: the role of radiation therapy and a review of the literature. Int J Radiat Oncol Biol Phys 1993;26: 491-7.
21. Stove J., Reichelt A. Massive osteolysis of the pelvis, femur and sacral bone with a Gorham-Stout syndrome. Arch Orthop Trauma Surg 1995; 114:207-10.
22. Hardegger F., Simpson L.A., Segmueller G. The syndrome of idiopathic osteolysis: classification, review and case report. J Bone Joint Surg [Br] 1985;67-B:89-93.
Review
For citations:
Otteva E.N., Kocherova T.Yu., Shepichev E.V., Otteva E.N., Kocherova T.Yu., Shepichev E.V. Massive osteolysis - gorham-stout syndrome. Osteoporosis and Bone Diseases. 2011;14(1):27-32. (In Russ.) https://doi.org/10.14341/osteo2011127-32
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