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Остеопороз и остеопатии

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НОВЫЕ НАПРАВЛЕНИЯ В ТЕРАПИИ ОСТЕОПОРОЗА - ПРИМЕНЕНИЕ МОНОКЛОНАЛЬНЫХ ЧЕЛОВЕЧЕСКИХ АНТИТЕЛ К RANKL (ДЕНОСУМАБ)

https://doi.org/10.14341/osteo2011223-26

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Аннотация

Обзор литературы посвящён патогенетической обоснованности, эффективности и безопасности применения деносумаба в терапии постменопаузального остеопороза. Обсуждается механизм действия препарата, сходства и отличия по отношению к другим препаратам для лечения остеопороза. Подробно представлены результаты II и III фаз клинических исследований деносумаба, в том числе в сравнении с алендроновой кислотой и возможности назначения деносумаба после лечения бисфосфонатами. Отдельное внимание уделяется безопасности и практическим аспектам терапии деносумабом

Об авторах

Zh Belaya

старший научный сотрудник отделения нейроэндокринологии и остеопатий, к.м.н


L Rozhinskaya

заведующая отделением нейроэндокринологии и остеопатий, д.м.н, профессор


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Для цитирования:


., . НОВЫЕ НАПРАВЛЕНИЯ В ТЕРАПИИ ОСТЕОПОРОЗА - ПРИМЕНЕНИЕ МОНОКЛОНАЛЬНЫХ ЧЕЛОВЕЧЕСКИХ АНТИТЕЛ К RANKL (ДЕНОСУМАБ). Остеопороз и остеопатии. 2011;14(2):23-26. https://doi.org/10.14341/osteo2011223-26

For citation:


Belaya Z.E., Rozhinskaya L.Y. NOVYE NAPRAVLENIYa V TERAPII OSTEOPOROZA - PRIMENENIE MONOKLONAL'NYKh ChELOVEChESKIKh ANTITEL K RANKL (DENOSUMAB). Osteoporosis and Bone Diseases. 2011;14(2):23-26. (In Russ.) https://doi.org/10.14341/osteo2011223-26

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ISSN 2072-2680 (Print)
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