Clinical case report of primary hyperparathyreoidism with fibrocystic osteitis: diagnostic difficulties
https://doi.org/10.14341/osteo13213
Abstract
Primary hyperparathyroidism (PHPT) is an endocrine disorder characterized by excessive secretion of parathyroid hormone, leading to multi-organ impairments that reduce patients’ quality of life. The disease is often diagnosed at the stage of bone complications, such as fibrous cystic osteitis (FCO), due to the lack of routine calcium screening. Misinterpretation of FCO as a neoplasm can result in unnecessary biopsies or surgical interventions. Key aspects of differential diagnosis include evaluation of laboratory parameters of calcium-phosphorus metabolism during the diagnostic process, as well as analysis of radiological and histological markers of PHPT. The presented clinical case demonstrates how a comprehensive assessment of data allows differentiation of metabolic bone lesions in PHPT, minimizing errors in treatment strategy.
About the Authors
A. S. Sudnitsyna
Tyumen state medical university
Россия
Россия
Anna S. Sudnitsyna, MD, PhD
54 Odesskaya street, 625000 Tyumen
D. Ts. Zurutova
Tyumen state medical university
Россия
Россия
Diana Ts. Zurutova, postgraduate student
Tyumen
L. A. Suplotova
Tyumen state medical university
Россия
Россия
Lyudmila A. Suplotova, MD, PhD, Professor
Tyumen
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For citations:
Sudnitsyna A.S., Zurutova D.Ts., Suplotova L.A. Clinical case report of primary hyperparathyreoidism with fibrocystic osteitis: diagnostic difficulties. Osteoporosis and Bone Diseases. 2025;28(3):46-54. (In Russ.) https://doi.org/10.14341/osteo13213
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